RESUMO
Non-clonal and clonal abnormal cells (hypodiploid, polyploid, and with chromosome aberrations) were detected by the G-method in the bone marrow and blood of the majority of patients with non-Hodgkin lymphomas before therapy. The manifestation of these abnormalities changed individually after treatment. The most incident were clones -22, del(1)(q42-43), del(2)(q-33-35), del(3)(q27), 4q-, and del(6q).
Assuntos
Células Sanguíneas/metabolismo , Medula Óssea/metabolismo , Citogenética/métodos , Linfoma não Hodgkin/genética , Adolescente , Adulto , Idoso , Aberrações Cromossômicas , Feminino , Humanos , Cariotipagem , Linfoma não Hodgkin/sangue , Linfoma não Hodgkin/terapia , Masculino , Pessoa de Meia-Idade , PoliploidiaRESUMO
Thermogenic effectiveness of electromagnetic irradiation (EMI) of UHF range (7 GHz) in the dependence on intensity (10-100 mW/cm2) and environmental temperature was studied in experiments with rabbits. Synergistic interaction of EMI and high ambient temperature was established. The existence of optimal EMI and high ambient temperature was established. The existence of optimal EMI intensity at which the synergy was maximal was shown. It is concluded that this interaction should be taken into account for hygienic standardization of nonionizing EMI.
Assuntos
Regulação da Temperatura Corporal/efeitos da radiação , Micro-Ondas , Temperatura , Animais , Meio Ambiente , CoelhosRESUMO
In experiments on laboratory animals it was found the different patterns of reactions in response to acute thermogenic 7 GHz CW microwave exposures. The effects were related specifically to the intensity of the field. SAR equal 0.5-0.7 power of basal metabolism of different species did not result in increase of body temperature. At SARs over intensity of basal metabolism (up to 1.5-2.0 basal metabolism for the mice and for the rats and up to 1.5 for the rabbits) the "stepped" pattern of body heating with periods of rectal temperature stabilization was observed. This results may have implications for prognostic estimation of dose-temporal limits of endurable intensities of microwaves.
Assuntos
Regulação da Temperatura Corporal/efeitos da radiação , Temperatura Corporal/fisiologia , Micro-Ondas/efeitos adversos , Lesões Experimentais por Radiação/fisiopatologia , Doença Aguda , Animais , Temperatura Corporal/efeitos da radiação , Regulação da Temperatura Corporal/fisiologia , Relação Dose-Resposta à Radiação , Camundongos , Camundongos Endogâmicos C57BL , Camundongos Endogâmicos CBA , Coelhos , Ratos , Ratos Wistar , Especificidade da EspécieRESUMO
The purpose of the investigation is the study of dose-response relationship at the antenatal exposure of low level ionizing radiation (137Cs, 1.0-1.25; 1.7-1.9 and 2.3-2.5 Gy during 20 days). The decrease of body weight in pregnant females and antenatal embryonic mortality at the doses 2.3-2.5 Gy are revealed. Physical postnatal anomalies with decrease of the adaptation were estimated by the strength endurance after antenatal exposure of gamma-rays at the doses of 1.0-2.5 Gy.