Appendiceal endometriosis: Case report of a rare differential diagnosis of acute appendicitis.

INTRODUCTION AND IMPORTANCE: Appendiceal endometriosis is an entity of extragonadal endometriosis. It commonly affects women of childbearing age with a wide spectrum of clinical manifestations. Women can present with symptoms mimicking acute appendicitis. Ultrasound, computed tomography scan (CT-Scan) and laparoscopy can be used for evaluation although the definitive diagnosis is obtained only with the histopathological study. CASE PRESENTATION: We report a case of appendiceal endometriosis presenting as acute right lower quadrant abdominal pain in a woman of childbearing age. CLINICAL DISCUSSION: We discuss appendiceal endometriosis as a rare differential diagnosis of acute appendicitis in young women and the diagnostic challenges this condition may pose to general surgeons. CONCLUSION: Appendiceal endometriosis is a rare condition with a challenging diagnosis. Although appendectomy relieves the acute symptoms, gynecological follow up is strongly recommended.

Laparoscopic transgastric resection of a gastric leiomyosarcoma: report of a rare case.

Gastric leiomyosarcoma is a rare type of tumour that is far less prevalent than gastrointestinal stromal tumours. We describe a case of a 42-year-old male patient who consulted for upper abdominal pain. Blood work revealed low haemoglobin levels, requiring red blood cell transfusions. An esophagogastroduodenoscopy was performed, showing a submucosal tumour with central ulceration in the greater gastric curvature. The patient underwent an endoscopic ultrasound with fine needle biopsy and the sample showed a spindle cell neoplasia. Computed tomography scan demonstrated absence of distant metastases. Upon multidisciplinary consensus, it was decided to perform surgery. A laparoscopic approach was conducted, where no peritoneal lesions were observed. Transgastric resection of the tumour was performed. Free tumour margins were achieved following oncologic criteria (minimum tumour manipulation and one-piece resection without damaging the tumour capsule). After exhaustive sampling, the final pathology report informed an 11 × 9 × 5 cm gastric leiomyosarcoma. Immunohistochemical examination showed positivity with smooth muscle actin, muscle-specific actin, calponin and desmin. The patient had an uneventful recovery, and 6 post-operative months' clinical, tomographic and endoscopic control informed no disease recurrence. To the best of our knowledge, there are less than 20 published cases of patients with diagnosis of gastric leiomyosarcoma. This study highlights the importance of reporting this entity, in order to contribute to the available literature concerning this topic.