Light-driven biocatalytic reduction of α,ß-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers.

Efficient and cost effective nicotinamide cofactor regeneration is essential for industrial-scale bio-hydrogenations employing flavin-containing biocatalysts such as the Old Yellow Enzymes. A direct flavin regeneration system using visible light to initiate a photoredox cycle and drive biocatalysis is described, and shown to be effective in driving biocatalytic activated alkene reduction. Using Ru(ii) or Ir(iii) complexes as photosensitizers, coupled with an electron transfer mediator (methyl viologen) and sacrificial electron donor (triethanolamine) drives catalytic turnover of two Old Yellow Enzymes with multiple oxidative substrates. Therefore, there is great potential in the development of light-driven biocatalytic systems, providing an alternative to the reliance on enzyme-based cofactor regeneration systems.

Cyclometalated Ir(III) complexes of deprotonated N-methylbipyridinium ligands: effects of quaternised N centre position on luminescence.

Six new tricationic Ir(III) complexes of cyclometalating ligands derived from 1-methyl-2-(2'-pyridyl)pyridinium or 1-methyl-4-(2'-pyridyl)pyridinium are described. These complexes of the form [Ir(III)(C^N)2(N^N)](3+) (C^N = cyclometalating ligand; N^N = α-diimine) have been isolated and characterised as their PF6(-) and Cl(-) salts. Four of the PF6(-) salts have been studied by X-ray crystallography, and structures have been obtained also for two complex salts containing MeCN and Cl(-) or two Cl(-) ligands instead of N^N. The influence of the position of the quaternised N atom in C^N and the substituents on N^N on the electronic/optical properties are compared with those of the analogous complexes where C^N derives from 1-methyl-3-(2'-pyridyl)pyridinium (B. J. Coe, et al., Dalton Trans., 2015, 44, 15420). Voltammetric studies reveal one irreversible oxidation and multiple reduction processes which are mostly reversible. The new complexes show intramolecular charge-transfer absorptions between 350 and 450 nm, and exhibit bright green luminescence, with λmax values in the range 508-530 nm in both aqueous and acetonitrile solutions. In order to gain insights into the factors that govern the emission properties, density functional theory (DFT) and time-dependent DFT calculations have been carried out. The results confirm that the emission arises largely from triplet excited states of the C^N ligand ((3)LC), with some triplet metal-to-ligand charge-transfer ((3)MLCT) contributions.

Crystal structure of [1,1'''-bis-(pyrimidin-2-yl)-4,4':2',2'':4'',4'''-quaterpyridine-1,1'''-diium-κ(2) N (1'),N (1'')]bis-[2-(pyridin-2-yl)phenyl-κ(2) N,C (1)]iridium(III) tris-(hexa-fluorido-phosphate) aceto-nitrile tris-olvate.

In the title compound, [Ir(C11H8N)2(C28H20N8)](PF6)3·3CH3CN or [Ir(III)(ppy)2{(2-pym)2qpy(2+)}](PF6)3·3CH3CN (ppy = deprotonated 2-phenyl-pyridine, pym = pyrimidyl and qpy = 4,4':2',2'':4'',4'''-quaterpyrid-yl), the Ir(3+) cation is coordinated by two C atoms and four N atoms in a slightly distorted octa-hedral geometry. The asymmetric unit consists of one complex trication, three hexa-fluorido-phosphate anions and three aceto-nitrile solvent mol-ecules. The average Ir-C distance is 2.011 (14) Å, the average Ir-N(ppy) distance is 2.05 (6) Šand the average Ir-N(qpy) distance is longer at 2.132 (10) Å. The dihedral angles within the 4,4'-bipyridyl units are 31.5 (6) and 23.8 (7)°, while those between the 2-pym and attached pyridyl rings are rather smaller, at 11.7 (9) and 7.1 (9)°. The title compound was refined as a two-component inversion twin.

Water-soluble Ir(iii) complexes of deprotonated N-methylbipyridinium ligands: fluorine-free blue emitters.

New blue or blue-green emitting iridium complexes have been synthesised with cyclometalating ligands derived from the 1-methyl-3-(2'-pyridyl)pyridinium cation. Efficient luminescence is observed in MeCN or aqueous solutions, with a large range of lifetimes in the µs region and relatively high quantum yields.

Synthesis, structures, and optical properties of ruthenium(II) complexes of the tris(1-pyrazolyl)methane ligand.

Four new complex salts [Ru(II)Cl(Tpm)(L(A))2][PF6]n [Tpm = tris(1-pyrazolyl)methane; n = 1, L(A) = pyridine (py) 1 or ethyl isonicotinate (EIN) 2; n = 3, L(A) = N-methyl-4,4'-bipyridinium (MeQ(+)) 3 or N-phenyl-4,4'-bipyridinium (PhQ(+)) 4] have been prepared and characterized. Electronic absorption spectra show intense d → π* metal-to-ligand charge-transfer (MLCT) absorption bands, while cyclic voltammetry reveals a reversible Ru(III/II) wave, accompanied by quasireversible or irreversible L(A)-based reductions for all except 1. Single crystal X-ray structures have been obtained for 1•Me2CO, 2, and 3•Me2CO. For 2-4, molecular first hyperpolarizabilities ß have been measured in acetonitrile solutions via the hyper-Rayleigh scattering (HRS) technique at 800 nm. Stark (electroabsorption) spectroscopic studies on the MLCT bands in frozen butyronitrile allow the indirect estimation of static first hyperpolarizabilities ß0. The various physical data obtained for 3 and 4 are compared with those reported previously for related cis-{Ru(II)(NH3)4}(2+) species [ Coe, B. J. et al. J. Am. Chem. Soc. 2005 , 127 , 4845 ]. TD-DFT calculations on the complexes in 1-4 confirm that their lowest energy absorption bands are primarily Ru(II) → L(A) MLCT in character, while Ru(II) → Tpm MLCT transitions are predicted at higher energies. DFT agrees with the Stark, but not the HRS measurements, in showing that ß0 increases with the electron-accepting strength of L(A). The 2D nature of the chromophores is evidenced by dominant ßxxy tensor components.