1.
Dalton Trans
; 45(26): 10500-4, 2016 Jul 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27277522
RESUMO
A simple approach towards efficient artificial proteases based on the cyclen ligand is presented. We thus achieved an increase of the proteolytic activity of two orders of magnitude when compared to the unsubstituted cyclen complex. Amphiphilic Cu(ii) and Co(iii) complexes cut BSA and myoglobin as model substrates at µM concentrations. MALDI-ToF MS is used to identify the cleavage fragments.