RESUMO
BACKGROUND: The aim of the present study was to evaluate the efficacy and safety of 3% polidocanol foam for treating 2nd-degree haemorrhoids. METHODS: A multicentre, open-label, single-arm, phase 2 trial involving 10 tertiary referral centres for haemorrhodal disease (HD) was performed. Between January and June 2019, patients with 2nd-degree haemorrhoids were prospectively included in this study. The primary outcome was to establish the success rate after one sclerotherapy session in terms of complete resolution of bleeding episodes one week after the injection. The Hemorrhoidal Disease Symptom Score (HDSS), the Short Health Scale for HD (SHS-HD) score and the Vaizey incontinence score were used to assess symptoms and their impact on quality of life and continence. Pain after the procedure, subjective symptoms and the amount and type of painkillers used were recorded. Patients were followed up for 1 year. RESULTS: There were 183 patients [111 males; 60.7%, mean age 51.3 ± 13.5 (18-75) years]. Complete resolution of bleeding was reached in 125/183 patients (68.3%) at 1 week and the recurrence rate was 12% (15/125). Thirteen patients (7.4%) underwent a second sclerotherapy session, while only 1 patient (1.8%) had to undergo a third session. The overall 1-year success rate was 95.6% (175/183). The HDSS and the SHS score significantly improved from a median preoperative value of 11 and 18 to 0 and 0, respectively (p < 0.001). There were 3 episodes of external thrombosis. No serious adverse events occurred. CONCLUSIONS: Sclerotherapy with 3% polidocanol foam is a safe, effective, painless, repeatable and low-cost procedure in patients with bleeding haemorrhoids.
Assuntos
Hemorroidas , Polidocanol , Escleroterapia , Adolescente , Adulto , Idoso , Feminino , Hemorroidas/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Polidocanol/efeitos adversos , Qualidade de Vida , Escleroterapia/efeitos adversos , Escleroterapia/métodos , Resultado do Tratamento , Adulto JovemRESUMO
Pilonidal disease (PD) is a relatively common, benign but challenging condition of the natal cleft. This consensus statement was drawn up by a panel of surgeons, identified by the Italian Society of Colorectal Surgery (SICCR) as having a "special interest" in PD, with the aim of recommending the best therapeutic options according to currently available scientific evidence. A three-step modified-Delphi process was adopted, implying: (1) choice of the panelists; (2) development of a discussion outline and of target issues; and (3) a detailed systematic review of the current literature. The agreement/disagreement level was scored on a five-point Likert scale as follows: "A + : strongly agree; A-: agree; N: unsure/no opinion; D-: disagree; D + : strongly disagree. Each panelist contributed to the production of this manuscript, and the final recommendations were reviewed by the Clinical Practice Guidelines Committee.
Assuntos
Cirurgia Colorretal , Procedimentos Cirúrgicos do Sistema Digestório , Consenso , Técnica Delphi , Humanos , Itália , Guias de Prática Clínica como AssuntoAssuntos
Cirurgia Colorretal , Coronavirus , Betacoronavirus , COVID-19 , Infecções por Coronavirus , Humanos , Itália , Pandemias , Período Perioperatório , Pneumonia Viral , SARS-CoV-2Assuntos
Procedimentos Cirúrgicos do Sistema Digestório/métodos , Pomadas/administração & dosagem , Seio Pilonidal/cirurgia , Cicatrização/efeitos dos fármacos , Administração Tópica , Adolescente , Adulto , Alginatos/administração & dosagem , Aloe , Colostro , Feminino , Glicerol/administração & dosagem , Humanos , Ácido Hialurônico/administração & dosagem , Itália , Masculino , Pessoa de Meia-Idade , Pomadas/química , Período Pós-Operatório , Resultado do Tratamento , Adulto JovemRESUMO
AIM: The management of haemorrhoids has changed significantly in the last two decades as a result of new insights into their pathophysiology and the availability of new surgical devices. The aim of this survey was to evaluate changes in the management of haemorrhoids in Italy over the last 17 years. METHOD: An electronic database which recorded details of management relating to the severity of haemorrhoids between 2000 and 2016 was obtained from 18 of 34 colorectal surgeons who were invited to participate. RESULTS: A total of 32 458 patients were treated for haemorrhoids by 18 expert coloproctologists during a 17-year period. Patients were classified as Grade II (7542, 23.2%), Grade III(15 360, 47.3%) and Grade IV (9556, 29.4%). Grade II haemorrhoids were treated with rubber band ligation in over 90% of the cases, and patients with Grade IV had a Milligan-Morgan (MM) haemorrhoidectomy in over 90% of the cases. In Grade III, the use of stapled haemorrhoidopexy progressively decreased from 30% to 35% (between 2000 and 2007) to 5% of the cases. Meanwhile, commencing from 2006 the use of Doppler-guided haemorrhoid artery ligation (DGHAL) with mucopexy increased progressively from 6% to 24%. Over the years, the percentage of MM haemorrhoidectomy remained consistent at between 65% and 70% of the cases. CONCLUSION: Relevant changes in the surgical choice of haemorrhoid treatment have occurred in Italy over the last 17 years. MM haemorrhoidectomy remains the most frequently performed procedure for Grade III haemorrhoids. Stapled haemorrhoidopexy has become much less popular in contrast to DGHAL with mucopexy which is being performed much more frequently.
Assuntos
Cirurgia Colorretal/tendências , Hemorroidectomia/tendências , Hemorroidas/cirurgia , Bases de Dados Factuais , Hemorroidectomia/métodos , Humanos , ItáliaRESUMO
AIM: Many different surgical techniques have been reported for the surgical treatment of full-thickness external rectal prolapse. Perianal stapled prolapse resection (PSP) is a relatively newly reported technique for full thickness external rectal prolapse. The aim of this prospective multicentre study was to evaluate the results of this procedure. METHOD: Consecutive patients who underwent a PSP resection for full-thickness external rectal prolapse at five centres were recruited to the study. Median operating time, hospital stay, complications, recurrence and functional results according to the Wexner Incontinence Scale and obstructive defaecation syndrome score were recorded. RESULTS: There were 27 patients treated by PSP. The median Wexner incontinence score improved from 10 presurgery to 5 after surgery (P < 0.001); the median obstructed defaecation syndrome score improved from 12 presurgery to 5 (range 4-10) after surgery (P < 0.001). A laparoscopically assisted procedure was performed in three patients (11.1%). The median number of cartridges used was six (range four to nine). The median operating time was 48 min. Early complications occurred in six patients (22.2%) and late complications in two (7.4%). The median length of hospital stay was 5 days. The recurrence rate at a median follow-up of 30.3 months was 14.8%. CONCLUSION: PSP appears to be an easy, fast and safe procedure. Early functional results are good. The recurrence rate compares favourably with other perineal procedures like the Delorme or the Altemeier operations. Long-term functional results need to be investigated further.
Assuntos
Prolapso Retal/cirurgia , Grampeamento Cirúrgico/métodos , Idoso , Idoso de 80 Anos ou mais , Constipação Intestinal/etiologia , Constipação Intestinal/cirurgia , Defecação/fisiologia , Incontinência Fecal/etiologia , Incontinência Fecal/cirurgia , Feminino , Seguimentos , Humanos , Obstrução Intestinal/etiologia , Obstrução Intestinal/cirurgia , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Períneo/cirurgia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Período Pós-Operatório , Período Pré-Operatório , Estudos Prospectivos , Prolapso Retal/complicações , Prolapso Retal/fisiopatologia , Recidiva , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
The Italian Society of Colorectal Surgery (SICCR.) has prepared clinical practice guidelines to help its members to optimize the treatment of pilonidal disease, a very common condition, especially among young people, and therefore of great importance on a socioeconomic level. The SICCR committee of experts on pilonidal disease analyzed the international literature and evaluated current evidence. Nonoperative management includes gluteal cleft shaving, laser epilation as well as fibrin glue and phenol injection: reported healing rates and recurrence incidence are satisfactory but the majority of studies are small series with low-quality evidence. Surgical therapy which can be divided into two categories: excision of diseased tissue with primary closure using different techniques or excision with healing by secondary intention. On the whole, no clear benefit is demonstrated for one technique over the other.
Assuntos
Cirurgia Colorretal/normas , Procedimentos Cirúrgicos do Sistema Digestório/métodos , Gerenciamento Clínico , Seio Pilonidal/terapia , Anti-Infecciosos Locais/uso terapêutico , Nádegas/patologia , Nádegas/cirurgia , Drenagem , Adesivo Tecidual de Fibrina/uso terapêutico , Remoção de Cabelo/métodos , Humanos , Itália , Fenol/uso terapêutico , Seio Pilonidal/classificação , Recidiva , Adesivos Teciduais/uso terapêuticoRESUMO
Results of personal experience of the application of enteral nutrition in a group of patients (21) submitted to surgery for gastric cancer are reported. Enteral nutrition proved easy to perform, provided a significant improvement in some of the parameters considered in the study, was without significant complications and presented acceptable management costs.
Assuntos
Nutrição Enteral , Cuidados Pós-Operatórios/métodos , Cuidados Pré-Operatórios/métodos , Neoplasias Gástricas/terapia , Idoso , Terapia Combinada , Nutrição Enteral/métodos , Feminino , Gastrectomia , Gastroenterostomia , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de TempoRESUMO
Data relating to a series of 22 patients suffering from primary gallbladder cancer are reported. In 8 cases the condition was benign, in 14 malignant. In 21 cases, concomitant presence of gallbladder calculosis was encountered. Survival in patients with gallbladder carcinoma was poor and significant in only 2 cases in which the tumour was observed at a non-advanced stage.
Assuntos
Neoplasias da Vesícula Biliar/diagnóstico , Adulto , Colecistectomia , Colelitíase/diagnóstico , Colelitíase/mortalidade , Colelitíase/cirurgia , Diagnóstico Diferencial , Feminino , Neoplasias da Vesícula Biliar/mortalidade , Neoplasias da Vesícula Biliar/cirurgia , Humanos , Excisão de Linfonodo , Masculino , Pessoa de Meia-IdadeRESUMO
A case of hydrosalpinx permagna with liquid content of fully 22 litres is reported. Historical and objective data are illustrated together with the operation performed, the postoperative course, follow-up and discussion of the case.