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ACS Macro Lett ; 10(3): 365-369, 2021 03 16.
Artigo em Inglês | MEDLINE | ID: mdl-35549058

RESUMO

Antibacterial materials containing biocides suffer from the fact that biocides are usually quickly released and hence display a limited antibacterial ability over a long period of time. To overcome this problem, the antibacterial agent 6-chloropurine is conjugated to a monomer via a hemiaminal ether linkage. The functional monomer is then reacted with a urethane acrylate by photopolymerization to yield thin polymer coatings. The release of the antibacterial agent from the coatings is sustained due to the slow kinetics of the hydrolysis of the hemiaminal ether linkage. Antibacterial performance is achieved against S. aureus and E. coli bacteria. This simple strategy can be applied for the rapid preparation of antibacterial coatings on various substrates and other applications such as antifouling or anticorrosion coatings.


Assuntos
Desinfetantes , Staphylococcus aureus , Antibacterianos/farmacologia , Escherichia coli , Éter , Éteres , Concentração de Íons de Hidrogênio , Polímeros/farmacologia
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