Assuntos
Hemangioendotelioma/patologia , Síndrome de Kasabach-Merritt/patologia , Sarcoma de Kaposi/patologia , Neoplasias Cutâneas/patologia , Abdome , Antineoplásicos Fitogênicos/uso terapêutico , Feminino , Hemangioendotelioma/tratamento farmacológico , Humanos , Recém-Nascido , Síndrome de Kasabach-Merritt/tratamento farmacológico , Sarcoma de Kaposi/tratamento farmacológico , Neoplasias Cutâneas/tratamento farmacológico , Resultado do Tratamento , Vincristina/uso terapêuticoAssuntos
Hemangioma/patologia , Meningomielocele/patologia , Anormalidades da Pele/patologia , Neoplasias Cutâneas/patologia , Antineoplásicos/administração & dosagem , Feminino , Hemangioma/tratamento farmacológico , Humanos , Lactente , Imageamento por Ressonância Magnética , Meningomielocele/tratamento farmacológico , Pomadas , Períneo , Propranolol/administração & dosagem , Anormalidades da Pele/tratamento farmacológico , Neoplasias Cutâneas/tratamento farmacológico , SíndromeRESUMO
Biochemical monitoring was performed on 113 sucklings affected with bronchiolitis in order to evaluate early onset of insufficient systemic perfusion. Values of haematic lactate, GPT and CPK levels in the serum, partial tension of haematic gases were evaluated on first day of hospitalization. Haemogasanalytic monitoring made it possible to differentiate two groups of infants: 21 patients with hypoxemia and 92 patients with normoxemia. Monitoring of lactatemia, CPK and GPT activity evidenced following values: hyperlactemia (66.6%), increased CPK levels (47.6%), increased GPT levels (14.2%) in the group of infants with hypoxemia. Hyperlactemia (55.4%), increased CPK levels (62%), increased GPT levels (19.5%) in the group of patients with normoxemia. These findings show no significant difference between the two groups and frequent occurrence of tissular hypoxia attributable to insufficient systemic perfusion. Moreover the results of such biochemical monitoring permit precise indication about appropriate treatment.
Assuntos
Bronquiolite Viral/sangue , Monitorização Fisiológica , Alanina Transaminase/sangue , Creatina Quinase/sangue , Humanos , Hipóxia/sangue , Lactente , Lactatos/sangueRESUMO
High frequency of bronchilitis, 70% of 1117 infants with respiratory infections, and clinical, radiological and laboratory features concerning partial tension of haematic gases, haematic lactate, enzymic activities of serum (CK, GPT, GOT) in 31 infants hospitalized with symptoms of shock in course of respiratory infections apparently affecting the upper respiratory tracts, are reported. This minimal respiratory pathology, evidenced in 3% of 1117 infants, defined as "minimal" viral pneumopathy, can be brought out trough a shock: lactacidosis, combined in half the cases with an increase of serum levels of CK and GPT and with normal PaO2 was ascertained in 87% of the cases. Three groups of bronchiolitis can be differentiated by haemogasanalytic monitoring: 1st group with a "serious" respiratory functional damage (hipercapnia hypoxemia), 14%. 2nd group with a "moderate" damage (normocapnia-hypoxemia), 20%. 3rd group with a "sligth" damage (hypocapnia-normoxemia), 66%. Decompensated shock is considered as a frequent occurrence and it is referred to the widespread involvement of the pulmonary circulation caused by the immunity-flogistic process.