Anti-NMDA Receptor Encephalitis During Pregnancy: A Case Report.

Anti-N-methyl-D-aspartate receptor (anti-MMDAR) encephalitis is an immune-mediated encephalitis mainly affecting young women.We describe the case of a 21-year-old woman who developed a classical form of anti-NMDAR encephalitis during the 10th week of gestation. The patient had been treated with methylpredinsolone and intravenous immunoglobulins. Birth history of the child was normal, with normal APGAR score. The clinical symptoms of the patient have improved after a few months.This rare occurrence during pregnancy (only 9 other cases described) presents an opportunity to highlight the importance of making the earliest possible diagnosis of this treatable and potentially reversible encephalitis, and to educate gynecologists, psychiatrists, anesthetists, and neurologists on this potential cause of psychiatric and neurological manifestations during pregnancy.

Unexpected finding on I-123 FP-CIT SPECT leading to the diagnosis of cerebral meningioma.

A 69-year-old woman with a 20-year history of psychiatric disorders was referred to our Nuclear Medicine Department because of an extrapyramidal syndrome. Because the differential diagnosis between neuroleptic-induced parkinsonism and Parkinson disease was difficult, I-123 FP-CIT brain SPECT was performed. The transverse slices demonstrated an unexpected image of the left striatum which seemed moved backward and toward the midline. A space occupying lesion was suspected and later confirmed by CT. This case highlights the significance of structural neuroimaging and of careful check of the striatum morphology.