RESUMO
The behaviour in hypothyroidism of certain muscular enzymes (CK, TOE, LDH, AST) was studied. A significant increase in these enzymes occurs in basal conditions and is gradually normalised by substitution therapy. This response might serve to distinguish hypothyroidism from other conditions causing an increase in muscular enzyme levels.
Assuntos
Hipotireoidismo/enzimologia , Músculos/enzimologia , Adulto , Idoso , Aspartato Aminotransferases/metabolismo , Creatina Quinase/metabolismo , Feminino , Humanos , Iodo/uso terapêutico , Isoenzimas , L-Lactato Desidrogenase/metabolismo , Masculino , Pessoa de Meia-Idade , Tireotropina/análise , Tiroxina/análise , Tri-Iodotironina/análiseRESUMO
The cardiovascular symptoms of six patients suffering from polymyositis were considered with reference to Pearson's classification. Transmural ischaemia type ventricular repolarisation anomalies were noted in two patients while clinica signis of cardiopathy were not present. A progressive disturbance in intraventricular condition was noted in one case. In another patient signs of atrial tachycardial type paroxysms with a variable A-V block were noted. Dilatative cardiomyopathy with progressive congestive decompensation and hyperkinetic ventricular arrhythmias were noted in two patients. These conditions responded partially to medical treatment. ECGraphic signs of pseudonecrosis and clinicoechographic signs of mitral valve prolapse were noted in another patient. These signs were not accompanied by either coronary or valvular clinical involvement equivalents.
Assuntos
Dermatomiosite/complicações , Cardiopatias/etiologia , Adulto , Eletrocardiografia , Feminino , Bloqueio Cardíaco/diagnóstico , Bloqueio Cardíaco/etiologia , Cardiopatias/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Prolapso da Valva Mitral/diagnóstico , Prolapso da Valva Mitral/etiologia , Taquicardia Paroxística/diagnóstico , Taquicardia Paroxística/etiologiaRESUMO
A series of 5 males and 2 females aged 23-73 yr with carcinoid cardiopathy is presented, all of them with clinical and instrumental signs of liver metastasis. The main clinical signs were dyspnoea and asthenia rendered ingravescent by effort, and, in the later stage, a frank picture of congestive cardiac decompensation. All subjected presented stethoscopic evidence of tricuspid valvulopathy, combined with pulmonary stenosis in 2 cases. The ECG picture displayed a constant reduction in cardiac potentials, together with right branch bundle block in 3 cases. In cases where an echocardiogram was taken, this confirmed tricuspid involvement. The disease progressed in all cases, and four patients died as a result of terminal liver failure.