RESUMO
AIM: The aim of the research was to study the dynamics of neurologic disorders in the context of combined therapy in patients with type 2 diabetes mellitus. MATERIAL AND METHODS: We examined 50 patients with diabetic polyneuropathy aged 50-70 years, with more than 12 months disease duration. The main group (n=30) included the patients who received 18 injections of Cocarnit against the background of hypoglycemic therapy. The control group patients (n=20) received only hypoglycemic therapy. The intensity and character of the pain on the background of the therapy was assessed on the TSS and NSS scales. An objective evaluation of the neurological status was performed using NDS. The state of the neuromotor apparatus was studied using stimulation electroneuromyography (ENMG) on motor fibers. RESULTS: As a result of the study, patients in the main group experienced a significant improvement in the NSS, TSS, NDS scales, as well as a decrease in the latent period, an increase in the M-response amplitude and n. peroneus impulse conduction rate. CONCLUSION: The obtained data confirm the efficacy and high safety profile of Cocarnit in the treatment of diabetic polyneuropathy in patients with type 2 diabetes.
Assuntos
Diabetes Mellitus Tipo 2 , Neuropatias Diabéticas , Idoso , Diabetes Mellitus Tipo 2/terapia , Humanos , Hipoglicemiantes , Pessoa de Meia-Idade , Músculo EsqueléticoRESUMO
For the determination of haemodynamic indices during the period of in adaptation in children there was examined 271 schoolboy from the gymnasium of the city of Krasnoyarsk There was studied the dynamics of haemodynamic indices in the course of adaptation, there were detected the degree of influence of haemodynamic indices on the process of adaptation, there were revealed features of haemodynamic indices in children with the various forecast of a course of adaptation. Children with the unfavorable forecast of adaptation to school had according to data of cardiorhythmography (CRG) low values of power in a range of slow waves during the period of restoration of the orthostatic test that testifies to the raised tone of sympathetic nervous system. There were established the correlation interrelationships of the forecast of adaptation of children to school with changed (raised, lowered) level of arterial pressure and Robinson's index value.
Assuntos
Adaptação Fisiológica/fisiologia , Hemodinâmica/fisiologia , Instituições Acadêmicas , Estudantes , Sistema Nervoso Simpático/fisiologia , Criança , Feminino , Humanos , MasculinoRESUMO
Three hundred and two Krasnoyarsk gymnasium students were examined to define criteria for determining the adaptation to high schooling loads. The values of the emotional status and adaptive processes were studied in children with varying resistance and varying mastering capacities; the impact of cardiovascular parameters on their adaptive process was defined The criteria for estimating the adaptation to high schooling loads were the presence or absence of acute chills and neurotic reactions, cardiovascular performance, and psychoemotional status.