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1.
Sci Rep ; 12(1): 15960, 2022 09 24.
Artigo em Inglês | MEDLINE | ID: mdl-36153393

RESUMO

Titanium dioxide nanoparticles (TiO2 NPs) were prepared by Caricaceae (Papaya) Shell extracts. The Nanoparticles were analyzed by UV-Vis spectrums, X-ray diffractions, and energy-dispersive X-rays spectroscopy analyses with a scanning electron microscope. An antifungal study was carried out for TiO2 NP in contradiction of S. sclerotiorums, R. necatrixs and Fusarium classes that verified a sophisticated inhibitions ratio for S. sclerotiorums (60.5%). Germs of pea were individually preserved with numerous concentrations of TiO2 NPs. An experience of TiO2 NPs (20%, 40%, 80% and 100%), as well as mechanisms that instigated momentous alterations in seed germinations, roots interval, shoot lengths, and antioxidant enzymes, were investigated. Associated with controls, the supreme seeds germinations, roots and plant growth were perceived with the treatments of TiO2 NPs. Super-oxide dis-mutase and catalase activities increased because of TiO2 NPs treatments. This advocates that TiO2 Nanoparticles may considerably change antioxidant metabolisms in seed germinations.


Assuntos
Carica , Caricaceae , Transferases Intramoleculares , Nanopartículas Metálicas , Nanopartículas , Antifúngicos/química , Antifúngicos/farmacologia , Antioxidantes/farmacologia , Catalase , Nanopartículas Metálicas/química , Nanopartículas/química , Óxidos , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Titânio/química , Titânio/farmacologia
2.
Phytother Res ; 26(4): 617-9, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21915932

RESUMO

Aloe vera gel is used traditionally for the treatment of skin diseases, including psoriasis. An ethanolic extract of the gel was assessed for antipsoriatic activity using a mouse tail model of psoriasis. The extract produced a significant differentiation in the epidermis, as seen from its degree of orthokeratosis (85.07 ± 3.36%) when compared with the negative control (17.30 ± 4.09%). This was equivalent to the effect of the standard positive control, tazarotene (0.1%) gel, which showed a 90.03 ± 2.00% degree of orthokeratosis. The ethanolic extract of Aloe vera leaf gel also produced a significant increase in relative epidermal thickness when compared with the control group, whereas the standard tazarotene showed no change. Taken together, the extract showed an overall antipsoriatic activity of 81.95%, compared with 87.94 for tazarotene, in the mouse tail model for psoriasis.


Assuntos
Aloe/química , Ácidos Nicotínicos/uso terapêutico , Fitoterapia , Extratos Vegetais/uso terapêutico , Folhas de Planta/química , Psoríase/tratamento farmacológico , Animais , Diferenciação Celular , Fármacos Dermatológicos/uso terapêutico , Modelos Animais de Doenças , Avaliação Pré-Clínica de Medicamentos , Epiderme/efeitos dos fármacos , Epiderme/patologia , Etanol/química , Ceratose/tratamento farmacológico , Ceratose/patologia , Masculino , Camundongos , Psoríase/patologia , Cauda/efeitos dos fármacos , Cauda/patologia
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