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1.
Artigo em Russo | MEDLINE | ID: mdl-29795092

RESUMO

Positron emission tomography combined with computed tomography (PET/CT) enables assessment of not only anatomical and structural but also metabolic changes in tumor mass. 18F-fluoroethyl tyrosine (18F-FET) PET/CT is based on evaluation of transport of 18F-labeled tyrosine in tissues. We present a clinical case of a patient with a newly diagnosed brain tumor, demonstrating the capabilities of 18F-FET PET/CT in assessing the reliable volume and degree of tumor anaplasia, which is important when choosing the treatment approach for a patient.


Assuntos
Neoplasias Encefálicas , Glioma , Encéfalo , Humanos , Imageamento por Ressonância Magnética , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Tomografia por Emissão de Pósitrons , Tirosina
3.
Artigo em Inglês, Russo | MEDLINE | ID: mdl-26529624

RESUMO

UNLABELLED: The study is devoted to the use of a minimally invasive method of SCT perfusion for the differential diagnosis of sellar and pаrаsellar tumors. Given a wide differential diagnostic range of tumors occurring in this area, the tumor perfusion indicators were used as an auxiliary diagnostic criterion. MATERIAL AND METHODS: The study analyzed outcomes in 115 patients with various tumors of the sellar area who underwent surgery or biopsy for histological verification of the diagnosis. RESULTS: The statistically significant differences were obtained for certain groups of tumors based on the values of hemodynamic parameters (p<0.05) that enable, with a high confidence, making a conclusion on the histologic type of most tumors. CONCLUSION: These findings demonstrated that SCT perfusion is a highly informative method of the preoperative differential diagnosis of these tumors. The sensitivity and specificity of SCT perfusion in the study were 100% and 81.2%, respectively.


Assuntos
Angiografia Cerebral , Neoplasias Hipotalâmicas/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adolescente , Adulto , Diagnóstico Diferencial , Humanos , Neoplasias Hipotalâmicas/patologia , Angiografia por Ressonância Magnética , Pessoa de Meia-Idade , Sensibilidade e Especificidade
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