1.
Vopr Med Khim
; 36(4): 88-90, 1990.
Artigo
em Russo
| MEDLINE
| ID: mdl-2238542
RESUMO
A new procedure is developed for purification of the antitumoral enzyme L-lysyl-alpha-oxidase from Trichoderma sp. The procedure included two steps: hydrophobic chromatography on butyl sylochrome C-80 and chromatography using biospecific sorbent AH-Sepharose. The simplified procedure enabled to increase distinctly the specific enzymatic activity from 30 to 50 IU/mg in the preparation obtained with a good yield.
Assuntos
Aminoácido Oxirredutases/isolamento & purificação , Trichoderma/enzimologia , Cromatografia/métodos
2.
Biull Eksp Biol Med
; 108(10): 476-7, 1989 Oct.
Artigo
em Russo
| MEDLINE
| ID: mdl-2597765
RESUMO
Evidences on the antileukemic effect of L-lysine alpha-oxidase from Trichoderma sp. are presented. It is inferred that enzyme needs detail studying as a potential chemotherapeutic drug both in experimental and clinical research.