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2.
Pract Neurol ; 18(1): 66-69, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29097555

RESUMO

Although neurological manifestations of systemic lupus erythematosus (SLE) are well recognised, myelopathy complicating SLE is rare. A 35-year-old woman presented with non-specific symptoms and a respiratory tract infection but had serological evidence of SLE. She subsequently deteriorated rapidly, developing a catastrophic spinal cord syndrome. Her initial MRI was normal; but after 1 month, her encephalopathy having progressed, repeat imaging showed characteristic myelitic changes. She responded only slowly to a combination of cyclophosphamide and corticosteroids. This case exemplifies the mixed presentations of SLE, including the under-recognised 'subpial leukomyelopathy' of central nervous system lupus. It highlights the challenges in managing lupus-related myelopathy and the benefits of a multidisciplinary approach to care.


Assuntos
Lúpus Eritematoso Sistêmico/complicações , Doenças da Medula Espinal/etiologia , Corticosteroides/uso terapêutico , Adulto , Complemento C3/metabolismo , Complemento C4/metabolismo , Feminino , Fator Estimulador de Colônias de Granulócitos/metabolismo , Humanos , Lúpus Eritematoso Sistêmico/diagnóstico por imagem , Lúpus Eritematoso Sistêmico/tratamento farmacológico , Imageamento por Ressonância Magnética , Medula Espinal/diagnóstico por imagem , Doenças da Medula Espinal/diagnóstico por imagem
3.
J Back Musculoskelet Rehabil ; 30(4): 681-689, 2017 Aug 03.
Artigo em Inglês | MEDLINE | ID: mdl-28655123

RESUMO

OBJECTIVE: The aim of the study was to gain information about the incidence of mechanical Low Back Pain (MLBP) injuries etiology in elite track and field athletes and to assess the recurrence rate. BACKGROUND: The prevalence and the etiology of Low Back Pain (LBP) in athletic populations at the elite level of competition lack of longitudinal studies focused on certain sport fields. The present study evaluates MLBP incidents in elite track and field athletes visiting National Track and Field Centre in Thessaloniki, Greece and classifies MLBP according to etiology. METHODS: One hundred and thirty Elite Track and Field Athletes with MLBP injuries were included in a 20-year observational cohort study recording the initial MLBP etiology according to a classification system based on mechanical diagnosis. It was examined if age, gender and sport category predispose the incidence of the initial MLBP etiology and if they consist risk factors for MLBP recurrence. RESULTS: Discogenic MLBP in elite track and field athletes was significantly higher at 46.9% (α= 0.05) compared with the other MLBP etiologies under consideration. Secondary findings of the present study regarding the incidence of MLBP etiology categories did not reveal significant associations with gender, age and contest categories (α= 0.05). Additionally, recurrence pathophysiology showed that discogenic MLBP obtained high recurrence rates at 0.48 (14 athletes from 29 athletes recurred) compared with other etiologies, followed by back elements injury recurrence rate at 0.24 (7 athletes out of 29). CONCLUSIONS: The study provided us with evidence of higher incidence of discogenic etiology of MLBP in elite track and field athletes. Further research is suggested in the use of etiology related LBP classification system in order to evaluate causes, prevalence and epidemiology of MLBP in athletic populations of specific sport categories.


Assuntos
Dor Lombar/epidemiologia , Dor Lombar/etiologia , Atletismo/lesões , Adolescente , Adulto , Atletas , Estudos de Coortes , Feminino , Grécia/epidemiologia , Humanos , Incidência , Masculino , Prevalência , Recidiva , Fatores de Risco , Adulto Jovem
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