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A system of two collinear probe beams with different wavelengths and pulse durations was used to capture simultaneously snapshot interferograms and streaked interferograms of laser produced plasmas. The snapshots measured the two dimensional, path-integrated, electron density on a charge-coupled device while the radial temporal evolution of a one dimensional plasma slice was recorded by a streak camera. This dual-probe combination allowed us to select plasmas that were uniform and axisymmetric along the laser direction suitable for retrieving the continuous evolution of the radial electron density of homogeneous plasmas. Demonstration of this double probe system was done by measuring rapidly evolving plasmas on time scales less than 1 ns produced by the interaction of femtosecond, high intensity, laser pulses with argon gas clusters. Experiments aimed at studying homogeneous plasmas from high intensity laser-gas or laser-cluster interaction could benefit from the use of this probing scheme.
RESUMO
In the scientific community, there is a growing interest in Tamarindus indica L. leaves, both as a valuable nutrient and as a functional food. This paper focuses on exploring its safety and antioxidant properties. A tamarind leaf fluid extract (TFE) wholly characterised was evaluated for its anti-DPPH activity (IC50 = 44.36 µg/mL) and its reducing power activity (IC50 = 60.87 µg/mL). TFE also exhibited a high ferrous ion-chelating capacity, with an estimated binding constant of 1.085 mol L(-1) while its influence over nitric oxide production in human leucocytes was irregular. At low concentrations, TFE stimulated NO output, but it significantly inhibited it when there was an increase in concentration. TFE was also classified as a non-toxic substance in two toxicity tests: the acute oral toxicity test and the oral mucous irritability test. Further toxicological assays are needed, although results so far suggest that TFE might become a functional dietary supplement.
Assuntos
Antioxidantes/química , Extratos Vegetais/química , Extratos Vegetais/toxicidade , Tamarindus/química , Animais , Cricetinae , Feminino , Humanos , Quelantes de Ferro/química , Leucócitos/efeitos dos fármacos , Óxido Nítrico/metabolismo , Folhas de Planta/química , Folhas de Planta/toxicidade , Ratos , Ratos Sprague-Dawley , Testes de Toxicidade AgudaRESUMO
Tamarind leaves are edible; however, their saponin content could be toxic to human blood cells. In this article, the effect of tamarind leaf fluid extract (TFE) on human blood cells was evaluated by using several tests. Results revealed that TFE did not cause significant haemolysis on human red blood cells even at the lowest evaluated concentration (20 mg/mL). Blood protein denaturalisation ratio was consistently lower than in control at TFE concentrations greater than 40 mg/mL. Erythrocyte membrane damage caused by the action of oxidative H2O2 displayed a steady reduction with increasing TFE concentrations. In the reactive oxygen species (ROS) measurement by using flow cytometry assay, leucocyte viability was over 95% at tested concentrations, and a high ROS inhibition was also recorded. Protective behaviour found in TFE should be attributed to its polyphenol content. Thus, tamarind leaves can be regarded as a potential source of interesting phytochemicals.
Assuntos
Tamarindus/química , Humanos , Peróxido de Hidrogênio/farmacologia , Oxirredução , Extratos Vegetais/sangue , Extratos Vegetais/química , Folhas de Planta/metabolismo , Espécies Reativas de Oxigênio/metabolismoRESUMO
We present experimental evidence supported by simulations of a relativistic ionization wave launched into a surrounding gas by the sheath field of a plasma filament with high energy electrons. Such a filament is created by irradiating a clustering gas jet with a short pulse laser (115 fs) at a peak intensity of 5×10(17) W/cm2. We observe an ionization wave propagating radially through the gas for about 2 ps at 0.2-0.5 c after the laser has passed, doubling the initial radius of the filament. The gas is ionized by the sheath field, while the longevity of the wave is explained by a moving field structure that traps the high energy electrons near the boundary, maintaining a strong sheath field despite the significant expansion of the plasma.
RESUMO
We measured the average deuterium cluster size within a mixture of deuterium clusters and helium gas by detecting Rayleigh scattering signals. The average cluster size from the gas mixture was comparable to that from a pure deuterium gas when the total backing pressure and temperature of the gas mixture were the same as those of the pure deuterium gas. According to these measurements, the average size of deuterium clusters depends on the total pressure and not the partial pressure of deuterium in the gas mixture. To characterize the cluster source size further, a Faraday cup was used to measure the average kinetic energy of the ions resulting from Coulomb explosion of deuterium clusters upon irradiation by an intense ultrashort pulse. The deuterium ions indeed acquired a similar amount of energy from the mixture target, corroborating our measurements of the average cluster size. As the addition of helium atoms did not reduce the resulting ion kinetic energies, the reported results confirm the utility of using a known cluster source for beam-target-fusion experiments by introducing a secondary target gas.
RESUMO
We report on experiments in which the Texas Petawatt laser irradiated a mixture of deuterium or deuterated methane clusters and helium-3 gas, generating three types of nuclear fusion reactions: D(d,^{3}He)n, D(d,t)p, and ^{3}He(d,p)^{4}He. We measured the yields of fusion neutrons and protons from these reactions and found them to agree with yields based on a simple cylindrical plasma model using known cross sections and measured plasma parameters. Within our measurement errors, the fusion products were isotropically distributed. Plasma temperatures, important for the cross sections, were determined by two independent methods: (1) deuterium ion time of flight and (2) utilizing the ratio of neutron yield to proton yield from D(d,^{3}He)n and ^{3}He(d,p)^{4}He reactions, respectively. This experiment produced the highest ion temperature ever achieved with laser-irradiated deuterium clusters.
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The plasma astrophysical S factor for the 3He(d,p)4He fusion reaction was measured for the first time at temperatures of few keV, using the interaction of intense ultrafast laser pulses with molecular deuterium clusters mixed with 3He atoms. Different proportions of D2 and 3He or CD4 and 3He were mixed in the gas target in order to allow the measurement of the cross section for the 3He(d,p)4He reaction. The yield of 14.7 MeV protons from the 3He(d,p)4He reaction was measured in order to extract the astrophysical S factor at low energies. Our result is in agreement with other S factor parametrizations found in the literature.
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Two different methods have been employed to determine the plasma temperature in a laser-cluster fusion experiment on the Texas Petawatt laser. In the first, the temperature was derived from time-of-flight data of deuterium ions ejected from exploding D(2) or CD(4) clusters. In the second, the temperature was measured from the ratio of the rates of two different nuclear fusion reactions occurring in the plasma at the same time: D(d,(3)He)n and (3)He(d,p)(4)He. The temperatures determined by these two methods agree well, which indicates that (i) the ion energy distribution is not significantly distorted when ions travel in the disassembling plasma; (ii) the kinetic energy of deuterium ions, especially the "hottest part" responsible for nuclear fusion, is well described by a near-Maxwellian distribution.
RESUMO
The kinetic energy of hot (multi-keV) ions from the laser-driven Coulomb explosion of deuterium clusters and the resulting fusion yield in plasmas formed from these exploding clusters has been investigated under a variety of conditions using the Texas Petawatt laser. An optimum laser intensity was found for producing neutrons in these cluster fusion plasmas with corresponding average ion energies of 14 keV. The substantial volume (1-10 mm(3)) of the laser-cluster interaction produced by the petawatt peak power laser pulse led to a fusion yield of 1.6×10(7) neutrons in a single shot with a 120 J, 170 fs laser pulse. Possible effects of prepulses are discussed.
Assuntos
Deutério/química , Deutério/efeitos da radiação , Lasers , Modelos Químicos , Nêutrons , Gases em Plasma/química , Gases em Plasma/efeitos da radiação , Simulação por Computador , Explosões , Fusão Nuclear , Eletricidade EstáticaRESUMO
Three types of neutron detectors (plastic scintillation detectors, indium activation detectors, and CR-39 track detectors) were calibrated for the measurement of 2.45 MeV DD fusion neutron yields from the deuterium cluster fusion experiment on the Texas Petawatt Laser. A Cf-252 neutron source and 2.45 MeV fusion neutrons generated from laser-cluster interaction were used as neutron sources. The scintillation detectors were calibrated such that they can detect up to 10(8) DD fusion neutrons per shot in current mode under high electromagnetic pulse environments. Indium activation detectors successfully measured neutron yields as low as 10(4) per shot and up to 10(11) neutrons. The use of a Cf-252 neutron source allowed cross calibration of CR-39 and indium activation detectors at high neutron yields (â¼10(11)). The CR-39 detectors provided consistent measurements of the total neutron yield of Cf-252 when a modified detection efficiency of 4.6×10(-4) was used. The combined use of all three detectors allowed for a detection range of 10(4) to 10(11) neutrons per shot.