RESUMO
OBJECTIVE: To determine the incidence of retinoblastoma (Rb) and the survival rate of patients with Rb in Puerto Rico. METHODS: This was a retrospective review of data from the Puerto Rico Central Cancer Registry (1985 - 2012). RESULTS: There were a total of 57 patients with Rb, with an overall incidence of 3.6 per 100,000 live births. By birth cohort, the incidence was 1 of every 29,393 live births. The mortality rate was 14.04% at 5 years. The incidence and the survival rate did not change over the 2 time periods that were compared: 1985 through 1998 and 1999 through 2012. CONCLUSION: The incidences of Rb are similar in Puerto Rico and the continental United States. However, our data indicate that the survival rate is lower in the former than it is in the latter. The incidence and the survival rate remained stable over the time studied.
Assuntos
Neoplasias da Retina , Retinoblastoma , Humanos , Incidência , Porto Rico , Sistema de Registros , Taxa de Sobrevida , Estados UnidosAssuntos
Infecções por Citomegalovirus/etiologia , Citomegalovirus/genética , Ceratoplastia Endotelial com Remoção da Lâmina Limitante Posterior/efeitos adversos , Endoftalmite/etiologia , Endotélio Corneano/patologia , Infecções Oculares Virais/etiologia , Infecção da Ferida Cirúrgica/etiologia , Idoso de 80 Anos ou mais , Doenças da Córnea/cirurgia , Infecções por Citomegalovirus/diagnóstico , Infecções por Citomegalovirus/virologia , DNA Viral/análise , Endoftalmite/diagnóstico , Endoftalmite/virologia , Endotélio Corneano/virologia , Infecções Oculares Virais/diagnóstico , Infecções Oculares Virais/virologia , Feminino , Humanos , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologiaRESUMO
Exophiala is a genus of slow-growing, melanin-producing, saprophytic fungi most commonly found in soil, faeces and decaying plant matter. It is an unusual fungal pathogen capable of causing a variety of ophthalmic manifestations, including keratitis, scleritis and endophthalmitis. In this report, we present a rare case of delayed-onset postoperative endophthalmitis confined to the anterior segment, secondary to Exophiala species. Previous reported cases of delayed-onset postoperative endophthalmitis have been treated medically, with suboptimal outcomes. Our experience supports the use of anterior segment surgery to clear the nidus of disease combined with intravitreal voriconazole to prevent recurrence of the infection.