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1.
Curr Pharm Biotechnol ; 22(3): 367-379, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-31696816

RESUMO

BACKGROUND: Oleaster or Elaeagnus angustifolia is a deciduous plant from Elaegnacea family and is well-known for its remedial applications. OBJECTIVE: This paper presents a comprehensive review of the potential application of Oleaster's flour incorporated in some food products. Emphasis is given to the physicochemical, biochemical, and functional properties of Oleaster's flour. METHODS: A comprehensive search was carried out to find publications on Oleaster's flour and its application as a prebiotic. The results of the related studies were extracted and summarized in this paper. RESULTS: Oleaster's flour as a prebiotic ingredient enhances antioxidants, polyphenols, fiber, flavonoids, Sterols, carbohydrates, and protein content of food products. CONCLUSION: Further advanced investigations on Oleaster and its functional ingredients revealed that these are efficacious and can be applied as a substitute source in pharmacological industries for medical applications.


Assuntos
Elaeagnaceae , Etnobotânica/métodos , Farinha/análise , Extratos Vegetais/análise , Prebióticos/análise , Animais , Anti-Inflamatórios/administração & dosagem , Anti-Inflamatórios/análise , Anti-Inflamatórios/química , Antioxidantes/administração & dosagem , Antioxidantes/análise , Antioxidantes/química , Cardiotônicos/administração & dosagem , Cardiotônicos/análise , Cardiotônicos/química , Elaeagnaceae/química , Flavonoides/administração & dosagem , Flavonoides/análise , Flavonoides/química , Humanos , Extratos Vegetais/administração & dosagem , Extratos Vegetais/química , Polifenóis/administração & dosagem , Polifenóis/análise , Polifenóis/química , Prebióticos/administração & dosagem
2.
Curr Pharm Biotechnol ; 21(15): 1576-1587, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32416671

RESUMO

In recent decades, functional foods with ingredients comprising probiotics, prebiotics and postbiotics have been gaining a lot of attention from scientists. Probiotics and postbiotics are usually applied in pharmaceutical formulations and/or commercial food-based products. These bioactive agents can be associated with host eukaryotic cells and have a key role in maintaining and restoring host health. The review describes the concept of postbiotics, their quality control and potential applications in pharmaceutical formulations and commercial food-based products for health promotion, prevention of disease and complementary treatment. Despite the effectiveness of probiotic products, researchers have introduced the concept of postbiotic to optimize their beneficial effects as well as to meet the needs of consumers to provide a safe product. The finding of recent studies suggests that postbiotics might be appropriate alternative agents for live probiotic cells and can be applied in medical, veterinary and food practice to prevent and to treat some diseases, promote animal health status and develop functional foods. Presently scientific literature confirms that postbiotics, as potential alternative agents, may have superiority in terms of safety relative to their parent live cells, and due to their unique characteristics in terms of clinical, technological and economical aspects, can be applied as promising tools in the drug and food industry for developing health benefits, and therapeutic aims.


Assuntos
Composição de Medicamentos/normas , Alimento Funcional , Prebióticos/microbiologia , Probióticos/uso terapêutico , Animais , Alimento Funcional/microbiologia , Alimento Funcional/normas , Humanos , Prebióticos/efeitos adversos , Probióticos/administração & dosagem , Probióticos/efeitos adversos
3.
Curr Pharm Biotechnol ; 21(12): 1224-1231, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32324509

RESUMO

BACKGROUND: Probiotics are the most widely consumed functional food. Consumers demand the production of foods also in low-calorie forms. OBJECTIVE: In this study, Lactobacillus casei 431 and various sweeteners were used in milk chocolate as probiotic and bulking agents, respectively. METHODS: Samples were prepared by using sucrose or optimum polyols combination. Chocolate samples were stored at two temperatures (4°C and 20°C) for 180 days and the viability of probiotic cells was controlled with the purpose of specifying the presented storage temperature. RESULTS: The highest probiotic viability was determined in the samples produced with sucrose and stored at 4°C. The cell counts were retained at the functional amount after maintenance for 6 months. Probiotic sucrose-free chocolate was more viscous than control chocolate, although displayed satisfactory sensory attributes. CONCLUSION: As a result, the sugared and sugar-free probiotic milk chocolates could be stored at room temperature. Due to the acceptable number of probiotic cells, the sucrose-free chocolates containing probiotics were considered as functional foods.


Assuntos
Chocolate , Lacticaseibacillus casei/crescimento & desenvolvimento , Viabilidade Microbiana/efeitos dos fármacos , Leite , Probióticos , Sacarose/farmacologia , Edulcorantes/farmacologia , Animais , Armazenamento de Alimentos , Alimento Funcional , Humanos , Lacticaseibacillus casei/efeitos dos fármacos , Leite/química , Leite/microbiologia , Reologia , Sacarose/análise , Edulcorantes/análise , Temperatura
4.
Curr Diabetes Rev ; 13(6): 582-589, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27758705

RESUMO

BACKGROUND: Diabetes mellitus, a condition of multifactorial origin, is related to the intestinal microbiota by numerous molecular mechanisms. Controlling the vast increase in the prevalence of diabetes needs a natural and safe solution. Probiotics, known as live microorganisms that exert health benefits to the host, have anti-diabetic property. OBJECTIVE: This review will highlight the current evidences in probiotic effectiveness and future prospects for exploring probiotic therapy in the prevention and control of diabetes. METHODS: We searched Pub Med and Science Direct by using "Probiotics" and "Diabetes" for searching the studies aiming the application of probiotics and the beneficial effects of probiotics in diabetes prevention and control. RESULTS: It has been shown that probiotics can increase insulin sensitivity and reduce autoimmune responses by modulating intestinal microbiota and decreasing the inflammatory reactions and oxidative stress. Recent evidences show that probiotics influences the host through modulating intestinal permeability and mucosal immune response, manipulating eating behaviors by appetite-regulating hormones and controlling gut endocannabinoid (eCB) system that is believed to be associated with inflammation and diabetes. Moreover, modulating the intestinal microbiota by probiotics controls host metabolism by affecting energy extraction from food and by biochemically converting molecules derived from the host or from gut microbes themselves. CONCLUSION: Experimental and clinical evidences support the hypothesis that the modulation of the gut microbiota by probiotics could be effective in prevention and management of diabetes.


Assuntos
Diabetes Mellitus/prevenção & controle , Diabetes Mellitus/terapia , Microbioma Gastrointestinal , Probióticos/uso terapêutico , Trato Gastrointestinal/microbiologia , Humanos , Inflamação/etiologia , Resistência à Insulina
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