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1.
Sci Rep ; 14(1): 10994, 2024 05 14.
Artigo em Inglês | MEDLINE | ID: mdl-38744832

RESUMO

In this paper, we propose a novel pricing model for delivery insurance in a food delivery company in Latin America, with the aim of reducing the high costs associated with the premium paid to the insurer. To achieve this goal, a thorough analysis was conducted to estimate the probability of losses based on delivery routes, transportation modes, and delivery drivers' profiles. A large amount of data was collected and used as a database, and various statistical models and machine learning techniques were employed to construct a comprehensive risk profile and perform risk classification. Based on the risk classification and the estimated probability associated with it, a new pricing model for delivery insurance was developed using advanced mathematical algorithms and machine learning techniques. This new pricing model took into account the pattern of loss occurrence and high and low-risk behaviors, resulting in a significant reduction of insurance costs for both the contracting company and the insurer. The proposed pricing model also allowed for greater flexibility in insurance contracting, making it more accessible and appealing to delivery drivers. The use of estimated loss probabilities and a risk score for the pricing of delivery insurance proved to be a highly effective and efficient alternative for reducing the high costs associated with insurance, while also improving the profitability and competitiveness of the food delivery company in Latin America.


Assuntos
Custos e Análise de Custo , Humanos , América Latina , Algoritmos , Aprendizado de Máquina , Seguro/economia , Modelos Econômicos
3.
An Acad Bras Cienc ; 95(2): e20200246, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37283327

RESUMO

Poisson distribution is a popular discrete model used to describe counting information, from which traditional control charts involving count data, such as the c and u charts, have been established in the literature. However, several studies recognize the need for alternative control charts that allow for data overdispersion, which can be encountered in many fields, including ecology, healthcare, industry, and others. The Bell distribution, recently proposed by Castellares et al. (2018), is a particular solution of a multiple Poisson process able to accommodate overdispersed data. It can be used as an alternative to the usual Poisson (which, although not nested in the Bell family, is approached for small values of the Bell distribution) Poisson, negative binomial, and COM-Poisson distributions for modeling count data in several areas. In this paper, we consider the Bell distribution to introduce two new exciting, and useful statistical control charts for counting processes, which are capable of monitoring count data with overdispersion. The performance of the so-called Bell charts, namely Bell-c and Bell-u charts, is evaluated by the average run length in numerical simulation. Some artificial and real data sets are used to illustrate the applicability of the proposed control charts.


Assuntos
Ecologia , Modelos Estatísticos , Simulação por Computador , Distribuição de Poisson
4.
An Acad Bras Cienc ; 93(suppl 3): e20190826, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34877968

RESUMO

The gamma distribution has been extensively used in many areas of applications. In this paper, considering a Bayesian analysis we provide necessary and sufficient conditions to check whether or not improper priors lead to proper posterior distributions. Further, we also discuss sufficient conditions to verify if the obtained posterior moments are finite. An interesting aspect of our findings are that one can check if the posterior is proper or improper and also if its posterior moments are finite by looking directly in the behavior of the proposed improper prior. To illustrate our proposed methodology these results are applied in different objective priors.


Assuntos
Teorema de Bayes , Raios gama
5.
PLoS One ; 16(11): e0258581, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34813589

RESUMO

This article focus on the analysis of the reliability of multiple identical systems that can have multiple failures over time. A repairable system is defined as a system that can be restored to operating state in the event of a failure. This work under minimal repair, it is assumed that the failure has a power law intensity and the Bayesian approach is used to estimate the unknown parameters. The Bayesian estimators are obtained using two objective priors know as Jeffreys and reference priors. We proved that obtained reference prior is also a matching prior for both parameters, i.e., the credibility intervals have accurate frequentist coverage, while the Jeffreys prior returns unbiased estimates for the parameters. To illustrate the applicability of our Bayesian estimators, a new data set related to the failures of Brazilian sugar cane harvesters is considered.


Assuntos
Teorema de Bayes , Simulação por Computador , Modelos Estatísticos , Probabilidade , Tamanho da Amostra
6.
PLoS One ; 16(8): e0255944, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34383829

RESUMO

In this paper, we propose a hierarchical statistical model for a single repairable system subject to several failure modes (competing risks). The paper describes how complex engineered systems may be modelled hierarchically by use of Bayesian methods. It is also assumed that repairs are minimal and each failure mode has a power-law intensity. Our proposed model generalizes another one already presented in the literature and continues the study initiated by us in another published paper. Some properties of the new model are discussed. We conduct statistical inference under an objective Bayesian framework. A simulation study is carried out to investigate the efficiency of the proposed methods. Finally, our methodology is illustrated by two practical situations currently addressed in a project under development arising from a partnership between Petrobras and six research institutes.


Assuntos
Modelos Estatísticos , Algoritmos , Teorema de Bayes , Indústria de Petróleo e Gás/economia , Robótica
7.
Lifetime Data Anal ; 27(4): 561-587, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34331190

RESUMO

In this paper, we propose a novel frailty model for modeling unobserved heterogeneity present in survival data. Our model is derived by using a weighted Lindley distribution as the frailty distribution. The respective frailty distribution has a simple Laplace transform function which is useful to obtain marginal survival and hazard functions. We assume hazard functions of the Weibull and Gompertz distributions as the baseline hazard functions. A classical inference procedure based on the maximum likelihood method is presented. Extensive simulation studies are further performed to verify the behavior of maximum likelihood estimators under different proportions of right-censoring and to assess the performance of the likelihood ratio test to detect unobserved heterogeneity in different sample sizes. Finally, to demonstrate the applicability of the proposed model, we use it to analyze a medical dataset from a population-based study of incident cases of lung cancer diagnosed in the state of São Paulo, Brazil.


Assuntos
Fragilidade , Neoplasias Pulmonares , Brasil , Humanos , Funções Verossimilhança , Modelos de Riscos Proporcionais , Análise de Sobrevida
8.
J Appl Stat ; 47(2): 306-322, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-35706514

RESUMO

In this paper, we introduce a new approach to generate flexible parametric families of distributions. These models arise on competitive and complementary risks scenario, in which the lifetime associated with a particular risk is not observable; rather, we observe only the minimum/maximum lifetime value among all risks. The latent variables have a zero-truncated Poisson distribution. For the proposed family of distribution, the extra shape parameter has an important physical interpretation in the competing and complementary risks scenario. The mathematical properties and inferential procedures are discussed. The proposed approach is applied in some existing distributions in which it is fully illustrated by an important data set.

9.
An Acad Bras Cienc ; 91(3): e20190002, 2019 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-31432908

RESUMO

In this paper, we revisit the Wilson-Hilferty distribution and presented its mathematical properties such as the r-th moments and reliability properties. The parameters estimators are discussed using objective reference Bayesian analysis for both complete and censored data where the resulting marginal posterior intervals have accurate frequentist coverage. A simulation study is presented to compare the performance of the proposed estimators with the frequentist approach where it is observed a clear advantage for the Bayesian method. Finally, the proposed methodology is illustrated on three real datasets.

10.
PLoS One ; 14(8): e0221332, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31469851

RESUMO

In this paper, from the practical point of view, we focus on modeling traumatic brain injury data considering different stages of hospitalization, related to patients' survival rates following traumatic brain injury caused by traffic accidents. From the statistical point of view, the primary objective is related to overcoming the limited number of traumatic brain injury patients available for studying by considering different estimation methods to obtain improved estimators of the model parameters, which can be recommended to be used in the presence of small samples. To have a general methodology, at least in principle, we consider the very flexible Generalized Gamma distribution. We compare various estimation methods using extensive numerical simulations. The results reveal that the penalized maximum likelihood estimators have the smallest mean square errors and biases, proving to be the most efficient method among the investigated ones, mainly to be used in the presence of small samples. The Simulated Annealing technique is used to avoid numerical problems during the optimization process, as well as the need for good initial values. Overall, we considered an amount of three real data sets related to traumatic brain injury caused by traffic accidents to demonstrate that the Generalized Gamma distribution is a simple alternative to be used in this type of applications for different occurrence rates and risks, and in the presence of small samples.


Assuntos
Lesões Encefálicas Traumáticas/epidemiologia , Modelos Estatísticos , Distribuições Estatísticas , Acidentes de Trânsito , Algoritmos , Lesões Encefálicas Traumáticas/fisiopatologia , Simulação por Computador , Hospitalização , Humanos , Funções Verossimilhança , Distribuição Normal
11.
Comput Math Methods Med ; 2016: 8727951, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27579052

RESUMO

We have considered different estimation procedures for the unknown parameters of the extended exponential geometric distribution. We introduce different types of estimators such as the maximum likelihood, method of moments, modified moments, L-moments, ordinary and weighted least squares, percentile, maximum product of spacings, and minimum distance estimators. The different estimators are compared by using extensive numerical simulations. We discovered that the maximum product of spacings estimator has the smallest mean square errors and mean relative estimates, nearest to one, for both parameters, proving to be the most efficient method compared to other methods. Combining these results with the good properties of the method such as consistency, asymptotic efficiency, normality, and invariance we conclude that the maximum product of spacings estimator is the best one for estimating the parameters of the extended exponential geometric distribution in comparison with its competitors. For the sake of illustration, we apply our proposed methodology in two important data sets, demonstrating that the EEG distribution is a simple alternative to be used for lifetime data.


Assuntos
Eletroencefalografia/métodos , Mortalidade Infantil , Algoritmos , Simulação por Computador , Bases de Dados Factuais , Diagnóstico por Computador , Infecções por HIV/sangue , Humanos , Lactente , Recém-Nascido , Análise dos Mínimos Quadrados , Funções Verossimilhança , Modelos Estatísticos , Método de Monte Carlo , Reconhecimento Automatizado de Padrão , Análise de Sobrevida
12.
Biotechnol J ; 3(8): 1088-93, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18618483

RESUMO

Agrobacterium tumefaciens technology is the battle horse for tomato genetic transformation. However, tomato varieties with low regeneration capacity are very difficult to transform. In the past, tomato transformation through Agrobacterium infection was focused on varieties capable of high regeneration yield, while successful transformation of low regenerable cultivars has not been reported. The genotype response to tissue culture conditions is believed to drive the frequency of regeneration of transgenic plant, whereas the capacity for cell proliferation could determine the transformation efficiency through this technology. The Campbell-28 cultivar is an example of constraints arising from a high morphogenetic potential with low conversion compared to normal plants. In the present work the roles that contribute to improved transgenic plant recovery from this recalcitrant variety were explored for factors like Agrobacterium concentration and antibiotics for bacterial removal and transformant selection. Analysis of the efficiency from independent transformation experiments revealed a more than twofold increase of transformant regeneration after selection on ammonium glufosinate compared to kanamycin selection, showing a transformation efficiency of 21.5%.


Assuntos
Técnicas de Cultura de Células/métodos , Vetores Genéticos/genética , Plantas Geneticamente Modificadas/fisiologia , Solanum lycopersicum/genética , Solanum lycopersicum/microbiologia , Transfecção/métodos , Transformação Genética/genética
13.
Transgenic Res ; 15(3): 291-304, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16779645

RESUMO

The whitefly-transmitted Tomato Yellow Leaf Curl Virus (TYLCV) is the major pathogen of tomato crop in Cuba and one of the most outstanding viral diseases of plants worldwide. In this work, we have developed transgenic tomato plants, transformed with an intron-hairpin genetic construction to induce post- transcriptional gene silencing against the early TYLCV replication associated protein gene (C1). The intron-hairpin RNA produced involves 726 nts of the 3' end of the TYLCV C1 gene as the arms of the hairpin, and the castor bean catalase intron. Transgenic tomato plants belonging to line 126, which harbor a single transgene copy, showed immunity to TYLCV, even in extreme conditions of infection (4-leaf-stage plants and 300 to many hundreds viruliferous whiteflies per plant during 60 days). Dot blot hybridization of these plants showed no TYLCV DNA presence 60 days after inoculation. Small interfering RNA molecules were detected in both inoculated and non-inoculated plants from line 126. These transgenic tomato plants of the otherwise very TYLCV-susceptible Campbell-28 tomato cultivar, are the first report of resistance to a plant DNA virus obtained by the use of the intron-hairpin RNA approach.


Assuntos
Genes de Plantas , Íntrons , Vírus de Plantas/genética , Vírus de Plantas/metabolismo , RNA/genética , Solanum lycopersicum/genética , Solanum lycopersicum/virologia , Inativação Gênica , Técnicas de Transferência de Genes , Técnicas Genéticas , Genoma , Modelos Genéticos , Doenças das Plantas , Plantas Geneticamente Modificadas , RNA Interferente Pequeno/metabolismo , Fatores de Tempo , Transcrição Gênica
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