RESUMO
The article is devoted to features of prenatal development of children with intestinal malrotation. Mass, height, head and chest circumferences of children after birth have been studied. In addition all associated malformations, a blood group (ABO system) and the rhesus-factor have been investigated. In comparison to the control group of newborn the disorders of prenatal development have included associated malformations, low anthropometric data after birth, decreasing of pA gene frequency. Notable, children with intestinal malrotation have had high frequency of malformations as in the abdominal and thoracic cavities as outside intestinal innervations: the small pelvis, the facial skeleton, the upper and lower extremity.
Assuntos
Sistema ABO de Grupos Sanguíneos/genética , Anormalidades Múltiplas/genética , Anormalidades do Sistema Digestório/genética , Intestinos/anormalidades , Sistema do Grupo Sanguíneo Rh-Hr/genética , Anormalidades Múltiplas/sangue , Anormalidades Múltiplas/embriologia , Anormalidades Múltiplas/epidemiologia , Anormalidades Múltiplas/cirurgia , Antropometria , Anormalidades do Sistema Digestório/sangue , Anormalidades do Sistema Digestório/embriologia , Anormalidades do Sistema Digestório/epidemiologia , Anormalidades do Sistema Digestório/cirurgia , Desenvolvimento Embrionário/genética , Feminino , Frequência do Gene , Humanos , Recém-Nascido , Intestinos/embriologia , Intestinos/inervação , Intestinos/cirurgia , MasculinoRESUMO
The enzymatic synthetic activity of peripheral blood lymphocytes was changed in the newborns whose mothers suffered from habitual miscarriages and were administered courses of metabolic therapy as part of combined pathogenetic treatment (basis therapy). Metabolic therapy brought about positive shifts which manifested by a reliable activation of succinate dehydrogenase and alpha-glycerophosphate dehydrogenase, this, in its turn, creating favorable conditions for the functioning of the mother-placenta-fetus metabolic system and being conductive to a better adaptation of the newborns in the early neonatal period. Metabolic therapy brought about a twofold reduction of the incidence of fetal hypoxia and hypotrophy.
Assuntos
Aborto Habitual/prevenção & controle , Glicerolfosfato Desidrogenase/sangue , Recém-Nascido/sangue , Linfócitos/enzimologia , Succinato Desidrogenase/sangue , Benzenossulfonatos/uso terapêutico , Dipiridamol/uso terapêutico , Congêneres do Estradiol/uso terapêutico , Feminino , Retardo do Crescimento Fetal/prevenção & controle , Hipóxia Fetal/prevenção & controle , Humanos , Hipnóticos e Sedativos/uso terapêutico , Parassimpatolíticos/uso terapêutico , Modalidades de Fisioterapia , Gravidez , Vasodilatadores/uso terapêutico , Niacinato de Xantinol/uso terapêuticoRESUMO
The dynamic study of the microecological state of the intestine in 41 newborns up to the age of 3 months has been made by biochemical and bacteriological investigation methods. The results of the biochemical rapid analysis have been found to be in complete agreement with those of the bacteriological analysis and, besides, to provide essential additional data. The biochemical rapid analysis permits the evaluation of the state resistance to the colonization of the intestine in children, starting from the age of 6 days. The presence of beta-alanine and ninhydrin-positive unidentified Nos. 7, 8a-1, 8d, 9, 10, 11 and 21 is indicative of a greater decrease in the level of the colonization of the digestive tract.
Assuntos
Antibacterianos/uso terapêutico , Intestinos/microbiologia , Ecologia , Fezes/química , Fezes/microbiologia , Humanos , Recém-Nascido , Intestinos/efeitos dos fármacos , Valores de Referência , Fatores de TempoRESUMO
With the aim to analyse the patterns and incidence of perinatal abnormalities, the history of pregnancy and the course of labour were studied in 400 recurrent spontaneous abortion cases. The course of the early neonatal period of these mothers' newborns was investigated and the follow-up history of 50 infants of this group was analysed. The findings indicated a high (62.8 per cent) incidence of perinatal damage in the studied group. The early neonatal period in the newborns was characterized by maladaptation and increased vulnerability followed by impairment of the mental and physical development.
Assuntos
Aborto Habitual/complicações , Doenças do Recém-Nascido/etiologia , Doenças do Prematuro/etiologia , Transtornos Psicomotores/etiologia , Pré-Escolar , Feminino , Humanos , Recém-Nascido , Doenças do Recém-Nascido/epidemiologia , Doenças do Prematuro/epidemiologia , Gravidez , Transtornos Psicomotores/epidemiologia , Fatores de Risco , U.R.S.S./epidemiologiaAssuntos
Recém-Nascido/imunologia , Linfócitos T/imunologia , Citometria de Fluxo , Humanos , Contagem de Leucócitos , Fenótipo , Receptores de Antígenos de Linfócitos T/análise , Receptores de Antígenos de Linfócitos T/imunologia , Linfócitos T/citologia , Linfócitos T Auxiliares-Indutores/citologia , Linfócitos T Auxiliares-Indutores/imunologia , Linfócitos T Reguladores/citologia , Linfócitos T Reguladores/imunologiaRESUMO
The authors determined activity of tumor-necrotizing factor in the blood serum from the umbilical cord and venous blood in children aged 5-6 years and in supernatants from the culture of mononuclear blood cells after its cultivation in the course of 24 h with bacterial products.