A LFP/AP Mode Reconfigurable Analog Front-End Combining an Electrical EEEG-iEEG Model for the Closed-Loop VNS.

This article presents a local field potential (LFP)/action potential (AP) mode reconfigurable analog front-end (AFE) dedicated for the closed-loop vagus nerve stimulator (VNS). It combines an inverse electrical model of the intracranial electroencephalogram (iEEG) conducting in the brain tissues and been recorded at scalp as the extended electroencephalogram (EEEG). The AFE contains a LFP/AP mode reconfigurable EEEG preamplifier, a tunable integrator to compensate the effect of either the recording electrodes or head tissues, and an adder. The LFP/AP mode reconfigurable EEEG preamplifier consists of a tunable chopper-stabilized amplifier (CSA) and a 2nd-order tunable low pass filter (LPF). For better separation of LFP and AP signals, a high-order DC servo loop (DSL) characterized as a 2nd-order DSL in parallel with a 1st-order DSL is exploited in the tunable CSA to achieve a tunable high-pass frequency with a stopband attenuation slope (SAS) of +40 dB/dec. In addition, the tunable LPF can obtain a tunable low-pass frequency with a SAS of -40 dB/dec and provide additional 20 dB gain for AP signals. Fabricated in a SMIC 180 nm CMOS technology, and in the LFP band (0.5 Hz-200 Hz) and AP band (300 Hz-5 kHz), the measured mid-band gains of the LFP/AP mode reconfigurable EEEG preamplifier are 39.6 dB and 59.5 dB, the input-referred noises (IRNs) are 2.2 µVrms and 6.3 µVrms, the DC/in-band input impedances are 1.27/1.26 GΩ and 0.3/0.22 GΩ, respectively. The power consumption per channel AFE is 6.3 µW, and the die area is 1.4 mm × 0.25 mm.

Novel High-Efficiency Nanocomposite Gate Design of Quantum-Dot Cellular Automata Based on Deep Learning.

With the development of science and technology, the feature size of CMOS devices will always shrink to the limit. Therefore, some new nanodevices will eventually become substitutes for microelectronic devices. A new electronic revolution will break out. Nanoscience and technology is the high-tech frontier technology of the century and one of the main contents of scientific development in the new era. Its development will have a profound impact on other disciplines, industries, and society. Nanoelectronics is an important part of the discipline of nanoscience and technology, which represents the development trend of microelectronics and will become the foundation of the next generation of electronic science and technology. With the development of ultra-large-scale integrated circuits, the feature size of electronic devices is getting smaller and smaller and has entered the nanoscale from the microscale. When the size of the system is small enough to be compared with the wavelength of electrons, the quantum effect becomes the dominant current-carrying main factor in child behavior. While these new phenomena and new effects bring challenges to the original semiconductor devices, they also provide opportunities for the development of new devices. Evolutionary circuit design is based on cellular neural network and quantum-dot cells, designs combinational logic circuits through the evolutionary algorithm, uses the logic gate based on cellular neural network design as the population gene of evolutionary circuit design, enriches the diversity of the population, and improves the evolutionary algorithm at the same time, the success rate of the improved genetic algorithm for evolutionary circuits has been greatly improved, and the failure rate has been reduced from 14% to 2%, obtaining a faster evolution speed and improving the performance of the evolution circuit.