RESUMO
In chronic pancreatitis patients was found persistent state of oxidative stress on the level of malonic aldehyde, which ran against the lowered levels of antioxidant enzymatic and non-enzymatic composition, and it has been found in the state of hypoproteinemia proteinogram indices (P < 0.05). The use of complex treatment of patients with chronic pancreatitis multivitamin-aminoacid drug Moriamin forte contributes to a significant regression effects oxidative stress and reduces the effects of hypoproteinemia (P < 0.05).
Assuntos
Antioxidantes/uso terapêutico , Fármacos Gastrointestinais/uso terapêutico , Hipoproteinemia/tratamento farmacológico , Pancreatite Crônica/tratamento farmacológico , 2-Piridinilmetilsulfinilbenzimidazóis/uso terapêutico , Adulto , Idoso , Aminoácidos/uso terapêutico , Ácido Ascórbico/sangue , Catalase/sangue , Domperidona/uso terapêutico , Feminino , Humanos , Hipoproteinemia/sangue , Hipoproteinemia/complicações , Hipoproteinemia/fisiopatologia , Peroxidação de Lipídeos/efeitos dos fármacos , Masculino , Malondialdeído/sangue , Pessoa de Meia-Idade , Estresse Oxidativo/efeitos dos fármacos , Pancreatina/uso terapêutico , Pancreatite Crônica/sangue , Pancreatite Crônica/complicações , Pancreatite Crônica/fisiopatologia , Pantoprazol , Inibidores da Bomba de Prótons/uso terapêutico , Superóxido Dismutase/sangue , Vitamina A/sangue , Vitaminas/uso terapêuticoRESUMO
The efficiency of long-term intermittent use of trinitrolong (TNL) and continuous oral use of sustac (ST) was compared in 44 patients with angina of effort, showing particularly good response to long-acting nitrates, as evidenced by paired bicycle ergometric tests. The efficacy of nitroderm (ND) adhesive tape applied on the skin was also assessed in 10 patients. TNL had better antianginal effect, and allowed a higher stress tolerance level, as compared to ST. ND was inferior to TNL and ST in terms of efficiency, apparently due to rapidly developing tolerance to its antianginal effect.