Assuntos
Blefaroptose , Toxinas Botulínicas Tipo A , Sobrancelhas , Fármacos Neuromusculares , Humanos , Toxinas Botulínicas Tipo A/administração & dosagem , Blefaroptose/induzido quimicamente , Fármacos Neuromusculares/administração & dosagem , Feminino , Solução Salina/administração & dosagem , Pessoa de Meia-IdadeAssuntos
Abrasão Química , Emulsificantes , Abrasão Química/métodos , Humanos , Fenol/uso terapêuticoRESUMO
Lichen planus pemphigoides (LPP) is a rare condition characterized by tense blisters that arise on lesions of lichen planus (LP) and on unaffected skin. We present the case of a 25-year-old pregnant woman at 12 weeks' gestation who developed an acute bullous eruption after 5 months of worsening LP. Similarities to pemphigoid gestationis (PG) included lesions around the periumbilical area and multiple urticarial erythematous papules and plaques in addition to linear C3 and IgM deposition along the basement membrane zone (BMZ) on direct immunofluorescence (DIF).
Assuntos
Líquen Plano/diagnóstico , Penfigoide Gestacional/diagnóstico , Complicações na Gravidez/diagnóstico , Corticosteroides/uso terapêutico , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Líquen Plano/tratamento farmacológico , Líquen Plano/patologia , Gravidez , Complicações na Gravidez/tratamento farmacológico , Complicações na Gravidez/patologiaRESUMO
Dissecting cellulitis of the scalp (DCS) is an uncommon inflammatory disease that often results in scarring alopecia. Numerous therapies have either proved ineffective or only temporarily effective in the management of this condition. Recent reports show adequate responses to tumor necrosis factor (TNF) inhibitors in cases of DCS. We report a case of severe recalcitrant DCS successfully treated with adalimumab.
Assuntos
Anti-Inflamatórios/uso terapêutico , Anticorpos Monoclonais Humanizados/uso terapêutico , Celulite (Flegmão)/tratamento farmacológico , Dermatoses do Couro Cabeludo/tratamento farmacológico , Dermatopatias Genéticas/tratamento farmacológico , Adalimumab , Adulto , Humanos , Masculino , Indução de RemissãoRESUMO
BACKGROUND/AIMS: surgical closure or reconstruction is commonly used to treat wounds generated by Mohs micrographic surgeries (MMS) and staged melanoma excisions, which may result in contractures and scarring. The authors' objective was to determine the value of using gelatin sponges to promote secondary intention healing for surgical defects after MMS and staged melanoma excisions. METHODS: sixty-four surgeries from 54 predominantly elderly patients (median age=76 years) were treated with gelatin sponges to promote healing by secondary intention in this prospective investigation. Patients rated their satisfaction with outcomes on a scale of 1 (highly dissatisfied) to 5 (highly satisfied). RESULTS: in all patients, the wounds healed within four to 16 weeks (median=five weeks). Forty-five patients were highly satisfied with their results (mean score=4.9). CONCLUSION: healing by secondary intention using gelatin sponges was associated with improved hemostasis, excellent cosmesis and a high level of patient satisfaction.