RESUMO
Neutrophilic eccrine hidradenitis is a variety of neutrophilic dermatosis described in patients with different neoplasms, most often leukaemia, and different chemotherapy regimens. It is characterised by neutrophilic infiltration of the eccrine coils of sweat glands. Recently it has been described in healthy juveniles, involving primarily the soles of the feet. We describe five new cases of juvenile neutrophilic eccrine hidradenitis all showing a good prognosis or a self-limiting course.
Assuntos
Dermatoses do Pé/complicações , Dermatoses do Pé/patologia , Hidradenite/complicações , Hidradenite/patologia , Adolescente , Pré-Escolar , Progressão da Doença , Feminino , Dermatoses do Pé/terapia , Hidradenite/terapia , Humanos , Masculino , Resultado do Tratamento , Vasculite/patologiaRESUMO
We present the case of a patient with negative serology asymmetric polyarthritis and erythematous-squamous cutaneous lesions of two years evolution, initially attributed to psoriasis, which histopathology (hyperkeratosis, epidermic infiltration due to atypical CD4+ lymphocytes with formation of Pautrier's microabscesses) together with hematological findings (persistent lymphocytosis with cells with cerebriform nucleus, 97% CD4+) allowed the diagnosis of Sézary's syndrome. To our knowledge, this is the eight documented case of arthritis in Sézary's syndrome and the first one with asymmetric chronic polyarthritis.
Assuntos
Artrite/patologia , Síndrome de Sézary/patologia , Neoplasias Cutâneas/patologia , Idoso , Artrite Psoriásica/patologia , Biópsia , Doença Crônica , Feminino , Humanos , Pele/patologia , Membrana Sinovial/patologiaRESUMO
We present the case of a 48-year-old premenopausal woman with right lumbosciatalgia secondary to osteoporosic vertebral collapses. Two of her three offsprings, a 31-year-old man and a 16-year-old woman, had chronic dorsolumbalgia, the study of which suggested the diagnosis of minor beta-thalassemia. As opposed to thalassemic osteoarthropathy, frequently observed in the forms of "major" and "minor" beta-thalassemia, rheumatic manifestations have almost never been described in the "minor" forms. We highlight the possibility of symptomatic osteoporosis as the first manifestation and we review the locomotive disorders associated to this hemoglobinopathy.
Assuntos
Osteoporose/etiologia , Talassemia/diagnóstico , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Talassemia/genéticaRESUMO
A higher incidence of Reiter's Syndrome (RS) is observed among young white men. We have conducted an epidemiological study of RS cases from our current health area and diagnosed in our hospital between 1975 and 1989. Twenty-four patients were included in this study, with a relation between men and women of 12:1 and an average age of 33.4 years. The annual incidence rate was 2.66 for men and 0.65 for women per 100,000 population during the study period. We have observed a tendency towards younger ages in the recent years and we have detected the presence of the HLA B-27 marker in 79% of patients.
Assuntos
Artrite Reativa/epidemiologia , Área Programática de Saúde , Feminino , Humanos , Incidência , Masculino , Espanha/epidemiologiaAssuntos
Artrite Juvenil/complicações , Doenças Linfáticas/etiologia , Fibrose Pulmonar/etiologia , Adolescente , Artrite Juvenil/diagnóstico por imagem , Doença Crônica , Feminino , Humanos , Pulmão/diagnóstico por imagem , Linfonodos/diagnóstico por imagem , Doenças Linfáticas/diagnóstico por imagem , Fibrose Pulmonar/diagnóstico por imagem , RadiografiaRESUMO
We report four patients (3 males and one female) suffering a sternoclavicular staphylococcal arthritis in whom risk factors such as parenteral drug addiction, alcoholism, diabetes, or immunosuppression were not observed. The etiopathogenesis, clinical picture, and diagnosis of this uncommon septic arthritis in reviewed.
Assuntos
Artrite Infecciosa , Infecções Estafilocócicas , Articulação Esternoclavicular , Artrite Infecciosa/diagnóstico , Artrite Infecciosa/etiologia , Artrite Infecciosa/microbiologia , Artrite Infecciosa/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/etiologia , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/patologiaRESUMO
A female in whom systemic lupus erythematosus had been diagnosed 5 years before suddenly developed headache and recurrent vomiting. Cranial computed tomography (CT) was consistent with subarachnoid hemorrhage, and cerebral arteriography disclosed cerebral aneurysms, multiple microaneurysms and cerebral vasculitis. After 7 days she developed left hemiparesis, and a cerebral infarct area was apparent in a new CT scan. Despite the poor prognosis of these lesions, the patient had a favorable outcome, without residual neurological deficit, after having been treated with intravenous corticosteroid boluses and oral cyclophosphamide.