Fibrous Dysplasia treated with virtual planning ­ report of two cases

Fibrous dysplasia (FD) is part of a rare group of bone dysplasia. It exhibits benign behavior and can lead to osteolytic lesions, deformities, and fractures. The treatment is challenging, and accurate removal of the lesion is necessary to restore function and esthetics. Here we present two cases of FD where virtual planning with presurgical computed tomography (CT) was used for the production of a surgical guide for bone contouring. First, CT image reconstruction was performed to mirror the patient's original anatomy. Then, three surgical guides that determined the area and depth of bone wear were prepared and used in the relevant sequence during the actual surgeries, which were successfully performed in both patients. This technique is termed the template guide holes (TGH) technique. The findings from this report suggest that presurgical virtual planning and guide preparation allows direct and objective measurement of the level of bone wear and improves the functional and esthetic outcomes of surgery for FD. In particular, the TGH technique is safe and allows adequate preoperative surgical simulation, reduces the surgical duration, and increases the predictability of the final result.

Fibrous Dysplasia treated with virtual planning - report of two cases.

Fibrous dysplasia (FD) is part of a rare group of bone dysplasia. It exhibits benign behavior and can lead to osteolytic lesions, deformities, and fractures. The treatment is challenging, and accurate removal of the lesion is necessary to restore function and esthetics. Here we present two cases of FD where virtual planning with presurgical computed tomography (CT) was used for the production of a surgical guide for bone contouring. First, CT image reconstruction was performed to mirror the patient's original anatomy. Then, three surgical guides that determined the area and depth of bone wear were prepared and used in the relevant sequence during the actual surgeries, which were successfully performed in both patients. This technique is termed the template guide holes (TGH) technique. The findings from this report suggest that presurgical virtual planning and guide preparation allows direct and objective measurement of the level of bone wear and improves the functional and esthetic outcomes of surgery for FD. In particular, the TGH technique is safe and allows adequate preoperative surgical simulation, reduces the surgical duration, and increases the predictability of the final result.

Avaliação Comparativa de Duas Técnicas de Moldagem da Cavidade Anoftálmica / Comparative Evaluation of Two Impression Techniques of the Anophthalmic Socket

Objetivo: A correta adaptação da prótese ocular na cavidade anoftálmica é fundamental para que ocorra uma boa mobilidade da prótese ocular, aspecto primordial na dissimulação da condição artificial presente em uma prótese ocular. Este trabalho avalia comparativamente a técnica de moldagem com seringa e seringa com moldeira acrílica em um grupo de 15 pacientes submetidos à enucleação do globo ocular. Método: Os grupos de estudo, constituídos de acordo com as técnicas de moldagem, foram avaliados mediante a confecção de corpos de prova em resina acrílica de lenta polimerização para observação do diâmetro transversal, diâmetro vertical e área das moldagens. Os corpos de prova foram submetidos à captação de imagens com lupa estereoscópica e câmara digital e as imagens foram processadas no programa ImageLab 2000®. Resultados: A análise estatística Postos Sinalizados de Wilcoxon (p≤0,05) mostrou que o diâmetro transverso foi semelhante em ambas as técnicas de moldagem. O menor diâmetro vertical observado com a técnica da seringa foi estatisticamente significante (p≤0,05). A área da superfície da mucosa da cavidade anoftálmica abrangida pela moldagem foi significantemente maior na técnica de moldagem com seringa e moldeira acrílica (p≤0,05). Conclusão: A técnica de moldagem com seringa e moldeira acrílica proporciona melhor direcionamento do material de moldagem no sentido súpero-inferior, o que determina uma maior área de contato da prótese com a superfície da mucosa. Considerando que a mobilidade de uma prótese ocular é dependente de uma boa adaptação da prótese na superfície da mucosa, pode-se inferir que a técnica de moldagem com seringa e moldeira acrílica acoplada deverá favorecer a mobilidade e a estética das próteses oculares

Objective: An excellent adaptation of the ocular prosthesis to the walls of the anophthalmic socket is fundamental to attain a good mobility of the artificial eye, a primordial aspect in dissimulating the artificial aspect of the prosthesis. This study compares the direct syringe impression technique to the impression taked with syringe and acrylic stock tray in a group of 15 patients submitted to eye enucleation. Methods: The study groups were established according to the impression technique employed and evaluated by means of specimens made of heat polymerizing resin in relation to transversal diameter, vertical diameter and area. The specimens were submitted to a stereoscopic glass and the images generated by a digital camera were processed by the software ImageLab 2000®. Results: The Wilcoxon rank-signed test (p≤0.05) showed that the transversal diameter was similar in both impression techniques. However, the smaller vertical diameter provided by the direct syringe technique was statiscally significant (p≤0.05). The area of the mucous surface of the anophthalmic socket registered during the impression taken with syringe and acrylic tray was significantly larger (p≤0.05). Conclusion: The syringe and acrylic tray impression technique provides a better distribution of the impression material, mainly in the superoinferior direction, and this accounts for the larger contact of the prosthesis with the mucous surface. Considering that the mobility of the ocular prosthesis is dependent of a good adaptation of the prosthesis on the mucous surface, the syringe and acrylic tray impression technique shall improve the mobility and aesthetics of ocular prosthesis

Dimensional accuracy of computer-aided design/computer-assisted manufactured orbital prostheses.

PURPOSE: The aim of this research was to assess the dimensional accuracy of orbital prostheses based on reversed images generated by computer-aided design/computer-assisted manufacturing (CAD/CAM) using computed tomography (CT) scans. MATERIALS AND METHODS: CT scans of the faces of 15 adults, men and women older than 25 years of age not bearing any congenital or acquired craniofacial defects, were processed using CAD software to produce 30 reversed three-dimensional models of the orbital region. These models were then processed using the CAM system by means of selective laser sintering to generate surface prototypes of the volunteers' orbital regions. Two moulage impressions of the faces of each volunteer were taken to manufacture 15 pairs of casts. Orbital defects were created on the right or left side of each cast. The surface prototypes were adapted to the casts and then flasked to fabricate silicone prostheses. The establishment of anthropometric landmarks on the orbital region and facial midline allowed for the data collection of 31 linear measurements, used to assess the dimensional accuracy of the orbital prostheses and their location on the face. RESULTS: The comparative analyses of the linear measurements taken from the orbital prostheses and the opposite sides that originated the surface prototypes demonstrated that the orbital prostheses presented similar vertical, transversal, and oblique dimensions, as well as similar depth. There was no transverse or oblique displacement of the prostheses. CONCLUSION: From a clinical perspective, the small differences observed after analyzing all 31 linear measurements did not indicate facial asymmetry. The dimensional accuracy of the orbital prostheses suggested that the CAD/CAM system assessed herein may be applicable for clinical purposes.

The pediatric patient at a maxillofacial service: Eye prosthesis.

Congenital absence or loss of the ocular globe during childhood causes psycho-social and cosmetic disorders and compromise the normal development of the orbital region. The literature relating to congenital or acquired etiology, due to trauma or disease, demonstrates the necessity of prevention and early detection in order to minimize the sequelae and disturbances in orbital growth. Installation of an eye prosthesis is essential to the rehabilitation process, so as to produce satisfactory development of the region. In order to characterize a profile of the child patient with this condition, a survey was carried out at the Prosthetic Eye sector, Out-patient Clinic, Discipline of Maxillofacial Prosthodontics, School of Dentistry, University of São Paulo (FOUSP), during the period from 1988 to 2003. The 124 (14.02%) patients within the age group of 0-13 years registered for ocular prosthesis were divided into a first group of 64 patients (51.62%) with 0-7 years, and a second group of 60 patients (48.38%) with 8-13 years. Fifty nine were girls and 65 were boys. No statistical significance was observed regarding the distribution of genders in the two analyzed age groups (p = 0.069). However, there was statistical significance at the level of 0.01 in relation to etiology, with higher prevalence of congenital and pathological disturbances in the younger group and traumatic occurrences in the older group. The etiology also presented variation according to the gender, at the significance level of 0.05, where girls presented three times less trauma than boys in the older age group. The necessity of prosthetic ocular repair was evenly distributed along the childhood period and the eye losses that required prosthetic treatment equally affected both genders. However, the etiology of eye loss varied according to the considered gender and age bracket.

The pediatric patient at a maxillofacial service: eye prosthesis / O paciente pediátrico em um serviço de prótese bucomaxilofacial: prótese ocular

Congenital absence or loss of the ocular globe during childhood causes psycho-social and cosmetic disorders and compromise the normal development of the orbital region. The literature relating to congenital or acquired etiology, due to trauma or disease, demonstrates the necessity of prevention and early detection in order to minimize the sequelae and disturbances in orbital growth. Installation of an eye prosthesis is essential to the rehabilitation process, so as to produce satisfactory development of the region. In order to characterize a profile of the child patient with this condition, a survey was carried out at the Prosthetic Eye sector, Out-patient Clinic, Discipline of Maxillofacial Prosthodontics, School of Dentistry, University of São Paulo (FOUSP), during the period from 1988 to 2003. The 124 (14.02 percent) patients within the age group of 0-13 years registered for ocular prosthesis were divided into a first group of 64 patients (51.62 percent) with 0-7 years, and a second group of 60 patients (48.38 percent) with 8-13 years. Fifty nine were girls and 65 were boys. No statistical significance was observed regarding the distribution of genders in the two analyzed age groups (p = 0.069). However, there was statistical significance at the level of 0.01 in relation to etiology, with higher prevalence of congenital and pathological disturbances in the younger group and traumatic occurrences in the older group. The etiology also presented variation according to the gender, at the significance level of 0.05, where girls presented three times less trauma than boys in the older age group. The necessity of prosthetic ocular repair was evenly distributed along the childhood period and the eye losses that required prosthetic treatment equally affected both genders. However, the etiology of eye loss varied according to the considered gender and age bracket.

A ausência congênita ou a perda do bulbo ocular na infância acarretam distúrbios estéticos e psico-sociais e comprometem o desenvolvimento normal da região orbitária. A literatura relacionada à etiologia congênita ou adquirida, devido a trauma ou doença, demonstra a necessidade da prevenção e da detecção precoce para minimizar as seqüelas e os distúrbios de crescimento orbital. A reabilitação implica a instalação de uma prótese ocular visando favorecer o desenvolvimento harmonioso da região. Com o objetivo de caracterizar o perfil do paciente infantil foi realizado um levantamento junto ao Setor de Prótese Ocular do Ambulatório da Disciplina de Prótese Bucomaxilofacial da FOUSP abrangendo o período de 1988 a 2003. As 124 (14,02 por cento) crianças registradas encontravam-se distribuídas em 64 (51,62 por cento) na faixa etária de 0 a 7 anos e 60 (48,38 por cento) na de 8 a 13 anos de idade, sendo 59 meninas e 65 meninos. A análise estatística revelou que a variação das ocorrências dos gêneros masculino e feminino nas faixas etárias não é significante (p = 0.069). Entretanto, a etiologia da perda variou segundo as faixas etárias consideradas, com um nível de significância de 0,01, apresentando uma maior prevalência de distúrbios congênitos e patológicos na faixa etária mais jovem e trauma na mais velha. A etiologia alterou-se de acordo com os gêneros com uma significância de 0,05, tendo as meninas apresentado três vezes menos trauma que os meninos na faixa etária mais velha. A necessidade de tratamento protético apresentou-se igualmente distribuída ao longo da infância e as perdas oculares que implicam reabilitação protética ocorreram igualmente nos gêneros masculino e feminino. Entretanto, a etiologia da perda ocular variou em função do gênero e da faixa etária considerada.

Reações teciduais às inclusões subcutâneas do polietileno poroso em ratos / Tissue reactions to subcutaneous porous polyethylene inclusions in rats

Este trabalho teve como objetivo verificar as reações teciduais, após a implantação de fragmentos quadrangulares de polietileno poroso (Polietileno poroso), na região subcutânea do dorso de ratos. Foram utilizados 27 ratos, machos e fêmeas, com peso corporal entre 250 e 300 g. Após a implantação do material, os animais foram divididos em nove grupos de 3 ratos cada um e sacrificados após decorridos 7, 14, 30, 60, 90, 120, 150, 180, 210 dias da cirurgia. As áreas contendo as inclusões foram removidas e fixadas em formol a 10%, incluídas em parafina e submetidas a análise histológica sob microscopia de luz. Os resultados obtidos possibilitaram concluir que o Polietileno poroso permitiu a penetração de tecido conjuntivo neoformado para o interior de seus poros, promovendo a boa aderência no local da sua implantação. Esse tecido neoformado apresentava-se bem vascularizado. Durante as análises dos períodos de observação, nenhum sinal de infecção foi constatado e o material não foi reabsorvido até o período final de 210 dias, sendo bem tolerado pelos tecidos hospedeiros, apesar de ocorrer um discreto infiltrado inflamatório crônico no último período de observação.