RESUMO
In order to know if the heavy metals stress condition is boon or bane for the plants growth, Lavandula dentata species was planted in pots under different levels of heavy metals stress condition and the phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of their leaf ethanolic extracts toward this stress condition were investigated compared to the control samples. Our findings showed significant differences in heavy metals bioaccumulation, photosynthetic pigments and total phenolic/flavonoids contents among L. dentata leafs ethanolic extracts, grown under different levels of heavy metals stress condition. The L. dentata leafs extracts, grown under Zn and Cu stress condition, showed the highest antioxidant and antimicrobial activities than those grown under Cd and Pb stress condition. Comparatively, the L. dentata leafs extracts, grown under Zn stress condition, showed higher antioxidant activity, and those, grown under Cu stress condition, showed higher antimicrobial activity. The highest cytotoxicity was showed by L. dentata leaf extracts, grown under Cd and Pb stress condition, which lead to conclude that these extracts could be served as a novel scaffold in search for new drugs against cancer. In conclusion, the highlighted variability reflects the high impact of heavy metals stress condition on phytochemical composition and consequently on the biological activities of medicinal plants. Such impact led to conclude that we should select medicinal plants extracts to be investigated carefully depending on this stress condition, in order to isolate the bioactive components or to have the best quality of extracts in terms of biological activities.
Assuntos
Anti-Infecciosos , Lavandula , Metais Pesados , Plantas Medicinais , Antioxidantes/farmacologia , Lavandula/química , Cádmio , Chumbo/toxicidade , Metais Pesados/toxicidade , Metais Pesados/química , Plantas Medicinais/química , Extratos Vegetais/farmacologia , Compostos Fitoquímicos/farmacologia , Anti-Infecciosos/farmacologiaRESUMO
The objective of this work is to develop an appropriate technology for environmentally sound membrane-based purification of a tannery effluent assuring, simultaneously, the recovery of chromium, considered as the most hazardous inorganic water pollutant extensively used in leather tanning. A comparison between the permeate fluxes obtained during treatment of a synthetic tannery effluent through nanofiltration (NF270 and NF90 membranes) and reverse osmosis (BW30 and SW30) membranes was first performed. Then, a dedicated polymeric membrane was prepared by coating chitosan (cs) on a polyethersulfone (PES) microfiltration membrane (cs-PES MFO22) support. The resulting membrane was characterized by Fourier Transforms Infrared Spectroscopy Attenuated Total Reflectance (FTIR-ATR), Emission Scanning Electronic Microscopy (SEM) to confirm the process of surface modification and cross-linking of chitosan with glutaraldehyde. This membrane was found to be highly effective for chromium removal (>99%), which was more than eight times higher in reference to monovalent cations (e.g., Na+ and K+) and more than six times higher in reference to the divalent cations (Mg2+ and Ca2+) studied. The reverse osmosis permeate conforms to local Algerian regulations regarding being discharged directly into the natural environment (in this case, Reghaia Lake) or into urban sewers linked to wastewater biological treatment stations. While the SW30 membrane proved to be the most effective for purification of the tannery effluent, the chitosan modified membrane proved to be appropriate for recovery of chromium from the reverse osmosis concentrate.