[Non-fortuitous dynamin II mutation-related association: neutropenia and Charcot-Marie-Tooth disease]. / Association non fortuite d'une neutropénie chronique et d'une maladie de Charcot-Marie-Tooth en rapport avec une mutation de la dynamine 2.

Charcot-Marie-Tooth (CMT) disease or hereditary motor and sensory neuropathy is a genetically and clinically heterogeneous group of disorders of the peripheral nervous system. Mutations in multiple genes are currently known. We report an original case of CMT associated with chronic neutropenia in a patient with a K562del mutation in the dynamin 2 (DNM2) gene in a patient presenting with alterated cognitive function. Associated manifestations may guide molecular study.

[Lipoatrophia semicircularis: a case report]. / La lipoatrophie semi-circulaire des cuisses : à propos d'un cas.

We report a 54-year-old man who presented bilateral, symmetric depressions on the anterior aspect of his thighs corresponding to lipoatrophia semicircularis. The origin of this distinctive variant of lipoatrophy is unknown. Repeated external microtraumatisms were considered to be the most plausible explanation. Recently, as many recently affected subjects shared a status of administrative employee, the role of electromagnetic fields generated by computers and their wirings has been discussed. Prevention proposal includes adapting work environment related to the use of computerized devices.