A Systematic Review on Assessing Assessments: Unveiling Psychometric Properties of Instruments for Reactive Attachment Disorder and Disinhibited Social Engagement Disorder in Minors under Protective Measures.

BACKGROUND: Reactive attachment disorder (RAD) and disinhibited social engagement disorder (DSED) manifest in individuals facing attachment system challenges, particularly observed in minors under protective measures. The lack of standardized tools for assessing these difficulties and uncertainty about the most effective instruments from a psychometric perspective prompted this study. AIM: Using the COSMIN checklist, we systematically reviewed instruments assessing RAD, adhering to PRISMA. METHODOLOGY: Examined tools included the Disturbance Attachment Interview, Preschool Age Psychiatric Assessment, Relationship Patterns Questionnaire, Assessment of RAD and DSED, Development and Well-Being Assessment, and Reactive Attachment Disorder Questionnaire. RESULTS: Of the 10 articles analyzed, the results highlight a research emphasis on internal consistency and structural and construct validity, sidelining other properties. CONCLUSION: Most articles review structural validity and internal consistency. These measures are satisfactory but insufficiently evaluated. It is necessary to evaluate these tools using other indicators such as cross-cultural validity, measurement error, or responsiveness in adolescents under protective measures.

Reactive Attachment Disorder and Its Relationship to Psychopathology: A Systematic Review.

This study aimed to determine, through a systematic review, the relationship between Reactive Attachment Disorder (RAD) and the presence of psychopathology in children and adolescents, and to determine the existence of differences in terms of internalising and externalising psychological problems between the RAD group and groups with other disorders or with typical development. Following the PRISMA methodology, a search was carried out in the Web of Science, PubMed and Scopus databases. The search yielded 770 results, of which only 25 met the inclusion criteria. The results indicate a relationship between the presence of RAD and/or disinhibited social engagement disorder (DSED), with the presence of internalising and externalising problems. These difficulties are more present in children with RAD compared to children without personal difficulties, or children with DSED, children with autism, children with intellectual disabilities or children with hyperactivity. It can be concluded that the presence of RAD has negative consequences on the mental health of children and adolescents, with these being greater in the inhibited group than in the disinhibited group, and with respect to children with autism or hyperactivity.

Health-Related, Social and Cognitive Factors Explaining Gambling Addiction.

BACKGROUND: Gambling addiction was the first addictive behavior not related to substance use that was recognized by the DSM-5. It shares diagnostics and comorbidity with other addictions. Extensive studies have investigated the clinical variables involved, but there have been fewer studies of related cognitive and social variables. In this research, an integrative model was developed to advance the understanding of gambling addiction, and an explanatory model was created based on the concept of cognitive distortions. METHODS: The sample comprised 258 university students (59.5% women) with a mean age of 20.95 years (SD = 2.19). A series of questionnaires were administered to measure gambling addiction, depression, coping with stress, prosocial behavior, susceptibility to priming and cognitive distortions about gambling. In addition, correlations, multiple linear regressions and a simple mediation model of these variables were analyzed. RESULTS: The results indicated that gambling addiction was correlated with a variety of clinical, social and cognitive factors. These factors contributed to a model that predicted 16.8% of the variance in gambling addiction and another model using cognitive distortions as a predictor and the maximum bet as a mediator that predicted 34.5% of the variance. CONCLUSIONS: The study represents an advance by developing a theoretical model from an integrative perspective and providing a new explanatory model. The findings of this research are of great importance in the development of prevention and intervention programs for gambling addiction.

Psychosocial risk factors of technological addictions in a sample of Spanish University students: The influence of Emotional (Dys)Regulation, personality traits and Fear of Missing Out on internet addiction.

Perception of the need to be online can lead to the compulsive use of the Internet. The aim of this study is to investigate the relationships between Internet Addiction and Social Media Addiction and some psychological variables that could influence the onset of these disorders (FoMO, Emotional Dysregulation, Personality traits). The sample was composed by 598 Spanish university students aged from 18 to 35 (471 women and 118 men; average age = 21.56; standard deviation = 2.73). Participants responded to an online questionnaire regarding the use of Internet (IAT), the use of social media (BSMAS), Fear of Missing Out (FoMO), Emotional (Dys)regulation (DERS) and personality traits (BFI-15). Correlation analysis showed a positive relationship between FoMO, Social Media Addiction, Internet Addiction, Emotional (Dys)regulation and Neuroticism dimension of Big five. Also, we observed a negative relationship between Internet Addiction and Social Media Addiction, Conscientiousness dimension of Big Five, and gender. The tested mediation model highlighted that the total effect of the DERS on the IAT score was significant as well as its indirect effect via the BSMAS and FoMO scores was positive and significant. In conclusion, we proposed a new integrated model for understanding the characteristics, predictors, and risk factors of IA.

Evaluation of Psychophysical Fitness in Drivers over 65 Years of Age.

BACKGROUND: The deterioration of cognitive and psychophysical ability associated with aging has an effect on road safety, especially in the driving of vehicles. The current study's main objective is to evaluate the psychophysical aptitudes in drivers over 65 years of age in a sample of drivers in Spain. METHODS: The sample was formed of a total of 1663 drivers who attended a Driver Recognition Center. The evaluation of their psychophysical aptitudes was carried out following the Medical-Psychological Exploration Protocol for Driver Recognition Centers, edited by the Ministry of Health and the General Directorate of Traffic. RESULTS: The results show increased restrictions in the evaluation of driving ability with age, which are especially significant after 75 years of age. Regarding sex, 70.1% of women have an approved evaluation, compared to men aged between 65-69, although from 69 onwards, the percentage of approved women decreases significantly. The loss of visual capabilities and poor performance in psycho-technical tests are the main causes associated with an evaluation with restrictions, with the number of restrictive conditions increasing with age. CONCLUSIONS: There is an increase in the number of cases with age-related restrictions, especially in the case of women and ophthalmologic-related problems, although the majority of drivers over 65 years old continue driving, thus continuing with a practice that has been related to the well-being and quality of life of older adults.

Effects of Cannabis Legalization on Road Safety: A Literature Review.

BACKGROUND: Legalizing medical and recreational cannabis and decriminalizing this substance may have unanticipated effects on traffic safety. The present study aimed to assess the impact of cannabis legalization on traffic accidents. METHODS: A systematic review was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) declaration of the articles included in the Web of Science (WoS) and Scopus databases. The number of papers included in the review was 29. RESULTS: The results show that in 15 papers, there is a relationship between the legalization of medical and/or recreational cannabis and the number of traffic accidents, while in 5 papers, no such relationship is observed. In addition, nine articles indicate a greater number of risk behaviors related to driving after consumption, identifying young, male, and alcohol consumption together with cannabis as the risk profile. CONCLUSIONS: It can be concluded that the legalization of medical and/or recreational cannabis has negative effects on road safety when considering the number of jobs that affect the number of fatalities.

Prospect Theory: A Bibliometric and Systematic Review in the Categories of Psychology in Web of Science.

Prospect Theory (PT) is an alternative, dynamic explanation of the phenomenon of risky decision making. This research presents an overview of PT's history in health fields, including advancements, limitations, and bibliometric data. A systematic and bibliometric review of the scientific literature included in the psychological categories of Web of Science (WoS) was performed following the PRISMA 2020 statement for systematic reviews. A total of 37 studies (10 non-empirical and 27 empirical) were included in the sample. Bibliometric results showed thematic variability and heterogeneity regarding the production, researchers, and methodologies that are used to study PT. The systematic results highlight three main fields of PT research: preventive and screening behaviors, promotion of healthy habits, and COVID-related decision making. Personal and contextual factors which alter the usual pattern specified by PT are also described. To conclude, PT currently has an interdisciplinary character suitable for health promotion, with recent studies broadening its applicability.

Decision Making in Addictive Behaviors Based on Prospect Theory: A Systematic Review.

Traditionally, research on addictive behaviors has been based on the study of their risk factors, with impulsivity being the main risk factor. However, this study aims to approach this topic from the analysis of decision making. According to the prospect theory, low levels of loss and risk aversion will increase the probability of showing addictive behaviors. A systematic review of the possible relationships between these behaviors and prospect theory was carried out. To this end, the works that have studied loss and risk aversion in populations with addictive behaviors to date (N = 15) were compiled. Apart from other eligibility criteria, the selection process was only performed with studies that included the prospect theory or cumulative prospect theory, in English or Spanish, since 1979. WoS, Scopus, Dialnet and PsycInfo were the information sources selected. For this purpose, PRISMA guidelines have been followed. It was found that users of addictive substances show less loss aversion than nonusers. These results cannot be transferred to pathological gamblers. The significance of this work for future research and the implementation of prevention and intervention programs is highlighted. The results show an approach to addictions from a novel perspective.

Social Support and Resilience as Predictors of Prosocial Behaviors before and during COVID-19.

The objective of this research was to analyze the relationship between social support and resilience with prosocial behavior before and during the confinement caused by COVID-19. Materials and Methods: The participants were divided into a confined group (228 women and 84 men) and an unconfined group (153 women and 105 men), all of whom were university students. Instruments were applied to measure the variables proposed. Results: Social support predicted 24.4% of the variance in prosocial behavior among women and 12% among men in the confined group; no evidence of this relationship was found in the unconfined groups. Resilience predicted 7% of the variance in prosocial behavior among confined women, 8.4% among confined men, 8.8% among unconfined women, and 5.1% in unconfined men. Discussion and Conclusion: The results show the importance of social support and resilience in prosocial behaviors, which are key elements for the proper functioning of society, especially in the face of a crisis such as COVID-19.

Sense of Coherence and Work Stress or Well-Being in Care Professionals: A Systematic Review.

Job-related stress affects the physical and psychological health of professionals dedicated to care. This work is a systematic review that aims to determine the relationships between a sense of coherence (SOC) and work stress and well-being perceived by care professionals. The review was carried out following the PRISMA guidelines, and the search was carried out using the Web of Science (WoS), PubMed, and Scopus databases, obtaining a final selection of 41 articles. The results indicate that stress, depression, burnout, and posttraumatic stress disorder (PTSD) negatively correlate with SOC; in contrast, job satisfaction, well-being, and quality of life positively correlate with SOC. It is concluded that SOC could act as a mediating variable and as a predictor variable of these health problems.

Motives for gambling, cognitive distortions, and irresponsible gambling: Proposal for an explanatory model of gambling addiction in university students.

There are many factors that appear to be directly related to the development of gambling addiction problems, and it is important to understand these relationships from a clinical perspective in order to develop prevention and intervention programs. This research seeks to analyze the relationships these problems have with gambling motives, cognitive distortions and irresponsible gambling behavior, and proposes an explanatory model of gambling addiction. The sample was made up of 258 adults residing in the province of Valencia (59.5% women), with a mean age of 20.95 years (SD = 2.19). A series of questionnaires were applied to measure the variables involved, and bivariate correlations, simple and multiple linear regressions and a structural equation model were analyzed. The results indicated that gambling motives were positively related to cognitive distortions, acting as predictors of these. Additionally, the proposed theoretical model showed goodness of fit on various indices and explained 69% of variance in cognitive distortions, 37% of that in irresponsible gambling and 43% of that in gambling addiction. The main limitation of this research is that the sample belongs to a very specific population, who did not necessarily have gambling problems. The main contributions are uncovering some of the relationships between gambling motives and cognitive distortions and the proposal of a mediating role of irresponsible gambling in the relationship between cognitive distortions and the development of gambling problems. If the proposed model replicates, it can be of help to research and health professionals.

Symbolic Play among Children with Autism Spectrum Disorder: A Scoping Review.

Symbolic play is considered an early indicator in the diagnosis of autism spectrum disorder (ASD) and its assessment. The objective of this study was to analyze the difficulties in symbolic play experienced by children with ASD and to determine the existence of differences in symbolic play among children with ASD, children with other neurodevelopmental disorders and children with typical development. A scoping review was carried out in the Web of Science (WoS), Scopus, ERIC, and PsycInfo databases, following the extension for scoping reviews of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. The number of papers included in the review was 22. The results confirm that children with ASD have greater difficulties with symbolic play than children with other neurodevelopmental disorders and children with typical development, even when controlling for their verbal age. Difficulties are greater in situations of free or spontaneous play. Results evidenced that the absence or deficiency in the symbolic play can serve as an early indicator of ASD between the first and second year of life, the developmental moment in which this type of play begins.

A Reliability Generalization Meta-analysis of the South Oaks Gambling Screen (SOGS).

BACKGROUND: The South Oaks Gambling Screen (SOGS) is one of the most widely used screening instruments for evaluating addiction to gambling. METHOD: The main objective of this study is to analyze whether the SOGS is a reliable instrument and what characteristics of studies on the SOGS are linked to its reported reliability. RESULTS: A meta-analysis was carried out with 63 studies including 65 independent samples. The mean value of a was .86 (95% CI of .84­.88), with high heterogeneity (I2 = 98.27%). The variables that explain the most heterogeneity were the continent where the study was performed (R2 = .61), application to participants with or without clinical problems (R2 = .58), the form of administration of the questionnaire (R2 = .56), and the standard deviation in the SOGS score (R2 = .13). CONCLUSIONS: The results show that the SOGS is a reliable instrument for evaluating gambling addiction. However, the meta-analysis highlights the need to report the reliability values for each empirical study and to provide a set of recommendations for researchers and professionals who use this instrument.

Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as α7 nAChRs Positive Allosteric Modulators.

The α7 nicotinic acetylcholine receptor (α7 nAChR) is a ligand-gated ion channel that is involved in cognition disorders, schizophrenia, pain, and inflammation. Allosteric modulation of this receptor might be advantageous to reduce the toxicity in comparison with full agonists. Our previous results obtained with some hydroxy-chalcones, which were identified as positive allosteric modulators (PAMs) of α7 nAChR, prompted us to evaluate the potential of some structurally related naturally occurring flavonoids and curcuminoids and some synthetic curcumin analogues, with the aim of identifying new allosteric modulators of the α7 nAChR. Biological evaluation showed that phloretin, demethoxycurcumin, and bis-demethoxicurcuming behave as PAMs of α7 nAChR. In addition, some new curcumin derivatives were able to enhance the signal evoked by ACh; the activity values found for the tetrahydrocurcuminoid analog 23 were especially promising.

From Emotional (Dys)Regulation to Internet Addiction: A Mediation Model of Problematic Social Media Use among Italian Young Adults.

Internet addiction (IA) has mostly been investigated with the fear of missing out and difficulties in emotional regulation. The present study examined the link between IA and variables related to problematic social media use (i.e., fear of missing out, social media addiction), together with emotional (dys)regulation and personality traits, providing new insights and an integrated assessment of IA. In total, 397 participants, aged 18-35 years (M = 22.00; SD = 3.83), were administered a set of questionnaires pertaining to IA, problematic social media use, emotional (dys)regulation, and personality traits. Pearson's correlations showed significant associations between IA and the investigated variables, and the tested mediation model highlighted the crucial role played by emotional (dys)regulation in the fear of missing out and problematic use of social networks. Overall, the findings provide support for a new integrated model for understanding the features, predictors, and risk factors of IA.

Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders.

The potential therapeutic use of some Cannabis sativa plant compounds has been attracting great interest, especially for managing neuropsychiatric disorders due to the relative lack of efficacy of the current treatments. Numerous studies have been carried out using the main phytocannabinoids, tetrahydrocannabinol (THC) and cannabidiol (CBD). CBD displays an interesting pharmacological profile without the potential for becoming a drug of abuse, unlike THC. In this review, we focused on the anxiolytic, antidepressant, and antipsychotic effects of CBD found in animal and human studies. In rodents, results suggest that the effects of CBD depend on the dose, the strain, the administration time course (acute vs. chronic), and the route of administration. In addition, certain key targets have been related with these CBD pharmacological actions, including cannabinoid receptors (CB1r and CB2r), 5-HT1A receptor and neurogenesis factors. Preliminary clinical trials also support the efficacy of CBD as an anxiolytic, antipsychotic, and antidepressant, and more importantly, a positive risk-benefit profile. These promising results support the development of large-scale studies to further evaluate CBD as a potential new drug for the treatment of these psychiatric disorders.

Biomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality.

During the last years, an extraordinary effort has been made to identify biomarkers as potential tools for improving prevention, diagnosis, drug response and drug development in psychiatric disorders. Contrary to other diseases, mental illnesses are classified by diagnostic categories with a broad variety list of symptoms. Consequently, patients diagnosed from the same psychiatric illness present a great heterogeneity in their clinical presentation. This fact together with the incomplete knowledge of the neurochemical alterations underlying mental disorders, contribute to the limited efficacy of current pharmacological options. In this respect, the identification of biomarkers in psychiatry is becoming essential to facilitate diagnosis through the developing of markers that allow to stratify groups within the syndrome, which in turn may lead to more focused treatment options. In order to shed light on this issue, this review summarizes the concept and types of biomarkers including an operational definition for therapeutic development. Besides, the advances in this field were summarized and sorted into five categories, which include genetics, transcriptomics, proteomics, metabolomics, and epigenetics. While promising results were achieved, there is a lack of biomarker investigations especially related to treatment response to psychiatric conditions. This review includes a final conclusion remarking the future challenges required to reach the goal of developing valid, reliable and broadly-usable biomarkers for psychiatric disorders and their treatment. The identification of factors predicting treatment response will reduce trial-and-error switches of medications facilitating the discovery of new effective treatments, being a crucial step towards the establishment of greater personalized medicine.

1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of α7 Nicotinic Receptors with Analgesic and Neuroprotective Activity.

Acetylcholine α7 nicotinic receptors are widely expressed in the brain, where they are involved in the central processing of pain as well as in neuropsychiatric, neurodegenerative, and inflammatory processes. Positive allosteric modulators (PAMs) show the advantage of allowing the selective regulation of different subtypes of acetylcholine receptors without directly interacting with the agonist binding site. Here, we report the preparation and biological activity of a fluoro-containing compound, 1-(2',5'-dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (8, RGM079), that behaves as a potent PAM of the α7 receptors and has a balanced pharmacokinetic profile and antioxidant properties comparable or even higher than well-known natural polyphenols. In addition, compound RGM079 shows neuroprotective properties in Alzheimer's disease (AD)-toxicity related models. Thus, it causes a concentration-dependent neuroprotective effect against the toxicity induced by okadaic acid (OA) in the human neuroblastoma cell line SH-SY5Y. Similarly, in primary cultures of rat cortical neurons, RGM079 is able to restore the cellular viability after exposure to OA and amyloid peptide Aß1-42, with cell death almost completely prevented at 10 and 30 µM, respectively. Finally, compound RGM079 shows in vivo analgesic activity in the complete Freund's adjuvant (CFA)-induced paw inflammation model after intraperitoneal administration.

Análisis del aborto desde un punto de vista conceptual / Abortion Analysis From a Conceptual Point of View / Análise do Abordo do Ponto de Vista Conceitual

Resumen El aborto se sitúa como uno de los más graves atentados contra la solidaridad intergeneracional porque ataca directamente la filiación. La diacronía establece el amparo del más débil y el amor entre padres e hijos. Esto se rompe desde las amenazas a la figura del hijo. Este artículo se desarrolla en el plano de los conceptos y la necesidad de contribuir a la vida en la sociedad actual. Para ello es necesario incidir en la dignidad de la vida humana en aquellos círculos académicos y de debate intelectual desde donde se crean las distintas corrientes de opinión.

Abstract Abortion is one of the most serious attacks against intergenerational solidarity because it directly attacks filiation. The diachrony establishes the protection of the weakest and the love between parents and children. This is broken from the attacks on the figure of the child. This paper moves in the concepts and the need to contribute in favor of life in today's society. For this, it is necessary to influence in favor of the dignity of human life in the academic and debate circles, spaces in which the different currents of opinion are created.

Resumo O aborto posiciona-se como um dos mais graves atentados contra a solidariedade intergeracional, porque ataca diretamente a filiação. A diacronia estabelece o amparo do mais fraco e o amor entre pais e filhos. Isso se quebra a partir das ameaças à figura do filho. Este artigo se desenvolve no plano dos conceitos e da necessidade de contribuir para a vida na sociedade atual. Para isso, é necessário incidir na dignidade da vida humana nos círculos acadêmicos e de debate intelectual, contextos em que são criadas as diferentes correntes de opinião.

Corrigendum: Sensory Processing in Children with Autism Spectrum Disorder and/or Attention Deficit Hyperactivity Disorder in the Home and Classroom Contexts.

[This corrects the article DOI: 10.3389/fpsyg.2017.01772.].