Confidence in COVID-19 vaccines moderates the association between vaccination status and mental distress.

Previous research has demonstrated that becoming vaccinated with the Coronavirus vaccine may lower mental distress. However, it remains uncertain whether this relationship holds amid concerns of vaccine side effects and doubts of the vaccine's protective capabilities. We presented three studies that showed how vaccine confidence negatively influences the relationship between vaccine uptake and mental distress. Using two-way fixed effects regression models, Study 1 analyzes longitudinal survey of respondents from Los Angeles County in the US, while Study 2 uses the same analytical strategy but generalises findings by analysing longitudinal data of participants across all 50 US states. Main results of both studies show that (i) vaccination uptake is linked with reduced mental distress among individuals with high vaccine confidence (ii) vaccine uptake has no effect on mental distress among individuals with low vaccine confidence. Lastly, Study 3 applies multilevel analysis to a large-scale pseudo-panel study of 15 developed countries. Results for the third study corroborate finding (i) but not (ii) in that the multinational study finds that vaccine uptake is actually associated with higher mental distress among individuals with low vaccine confidence. In sum, our paper shows that the palliative effect of vaccination on mental health only exists when vaccine confidence is high. Results are mixed on whether vaccination affects mental distress when individual vaccine confidence is low.

Improving vaccination intent among skeptics through confidence in governments' handling of the COVID-19 pandemic.

Scientific evidence suggests that individuals vaccinated with COVID-19 vaccines are less likely to require hospitalization, possibly lowering the burden on the healthcare system. Despite such benefits, substantial segments of the world's population remain skeptical of COVID-19 vaccines and are hesitant to take them. Even if such individuals have been inoculated with COVID-19 vaccines out of economic, social, or legal necessity, they may be less inclined to receive booster shots or vaccinate their offspring when such options become available. What might help reduce this hesitancy? We examined this question using nationally representative survey data across 15 developed countries (max N = 122,516). Our findings suggest that inspiring confidence in the government's handling of the pandemic is pivotal in enhancing vaccination intent among vaccine skeptics. Specifically, results from a hierarchical linear analysis showed that among vaccine skeptics, confidence in the government's management of the pandemic was associated with greater intent to (a) take COVID-19 vaccines (b) take booster shots and (c) vaccinate one's children.