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1.
Int J Dent Hyg ; 9(2): 163-6, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21356010

RESUMO

BACKGROUND: The presence of atrophic-erosive lesions among gingival tissues makes oral hygiene procedures difficult for several reasons. Plaque control and rigorous oral hygiene are a fundamental requisite for the treatment of any oromucosal disease. CASE REPORT: A patient suffering from a mixed atrophic-erosive form of oral lichen planus (OLP), with serious gingival involvement, was also treated with the topical application of clobetasol propionate 0.05% using gingival trays. The highest hygiene standards of both patient and trays were of fundamental importance. DISCUSSION: The management of the patient suffering from gingival atrophic-erosive OLP requires the synergic treatment of both dentist and dental hygienist, whose contribution supports the corticosteroid and/or immunosuppressive treatment.


Assuntos
Anti-Inflamatórios/administração & dosagem , Clobetasol/administração & dosagem , Doenças da Gengiva/tratamento farmacológico , Líquen Plano Bucal/terapia , Higiene Bucal/métodos , Administração Tópica , Assistência Odontológica para Doentes Crônicos/métodos , Doenças da Gengiva/complicações , Humanos , Líquen Plano Bucal/complicações , Masculino , Pessoa de Meia-Idade , Educação de Pacientes como Assunto , Resultado do Tratamento
2.
Int J Immunopathol Pharmacol ; 23(2): 677-81, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20646367

RESUMO

The anti-Cyclic Citrullinated Peptide Antibodies (anti-CCP) are produced locally in the inflamed synovium of Rheumatoid arthritis (RA) patients, suggesting that citrullinated proteins are located in the inflamed synovium. In scientific literature were find periodontal bacterial DNA in serum and synovial fluid of RA with PD patients. RA and adult periodontitis share common pathogenetic mechanisms and immunologic and pathological findings RA. One oral pathogen strongly implicated in the pathogenesis of periodontal disease (PD), Porphyromonas. gingivalis, possesses a unique microbial enzyme, peptidylarginine deiminase (PAD), the human equivalent of which has been identified as a susceptibility factor for RA. Under this point of view, we speculate about the presence of anti-CCP antibodies in sera of PD with RA patients. We conducted this study to evaluate and compare the diagnostic and predictive utility of anti-CCP antibodies in patients with PD and patients with PD and RA. Anti-CCP antibody was not found in 21 sera (U/ml<10), included RA controls, while only 1 patient with chronic PD and probing depth of 7,1 mm was identified positive for anti-CCP (22.2 U/ml). Our data do not support a role for anti-CCP in diagnoses of periodontal disease.


Assuntos
Autoanticorpos/sangue , Peptídeos Cíclicos/imunologia , Doenças Periodontais/diagnóstico , Adulto , Idoso , Artrite Reumatoide/etiologia , Autoanticorpos/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
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