[The question of mechanisms of the immunotropic effect of mineral drinking waters]. / K voprosu o mekhanizmakh immunotropnogo deistviia pit'evykh mineral'nykh vod.

Drinking of mineral waters influences human immune system. Among the mechanisms of this action is a stress effect confirmed by increasing levels of glucocorticoids, catecholamines, by hyperglycemia, etc. Regular drinking of mineral water brings about adaptation. Development of long-term adaptation provokes defensive cross effects. It is suggested that an immunotropic action of mineral waters may be a manifestation of a defensive cross effect of the organism adaptation. Immunostimulation may also be related to suppression of T-suppressors activity and changes in cytokines levels.

[Effects of sodium hydrogen carbonate-chloride-containing mineral water on stress sensitivity in rats]. / Otsenka vliianiia gidrokarbonatno-khloridnoi natrievoi mineral'noi vody na chuvstvitel'nost' krys k deistviiu stressa.

The investigation used the mineral water (MW) Uralochka obtained from well 4638 located on the territory of the sanatorium Ural (the village of Khomutino, Chelyabinsk Region). Experimental findings suggest that the use of the Uralochka water for 14 days lowers experimental animals' sensitivity to stress. This is manifested by that MW use virtually completely eliminated the hematological manifestations of stress, poststress depression of a cell immunity response and prevented the reduction of cell counts in the abdominal cavity. The immunostimulating effect of the Uralochka MW on humoral immunity and the phagocytosis of peritoneal macrophages preserved with the combined influence of stress and MW.

[An evaluation of the effect of sodium bicarbonate-chloride mineral water on the rat immune system]. / Otsenka vliianiia gidrokarbonatno-khloridnoi natrievoi mineral'noi vody na immunnuiu sistemu krys.

Mineral water Uralochka tried in rats is obtained from the spring in the territory of the sanatorium Ural (Chelyabinsk Province). The mineral water contains chloride, hydrocarbonate ions and sodium cations, mineralization is 4.13 g/dm3. A 15-day course of Uralochka drinking did not influence much reaction of delayed hypersensitivity, but increased the absolute number of antibody-forming cells by 95.86%, raised the ability of peritoneal macrophages to absorb latex particles. Thus, mineral water Uralochka can raise intensity of humoral immune response and the ability of macrophages for phagocytosis of the latex particles. Phagocytosis activity and intensity increased by 48.27 and 62.13%, respectively.