Comparison of intravenous pantoprazole and ranitidine in patients with dyspepsia presented to the emergency department: a randomized, double blind, controlled trial.

BACKGROUND: This study aimed to compare pantoprazole, a proton-pomp inhibitors (PPIs), and ranitidine, a H2 receptor antagonists (H2RA), in ceasing dyspeptic symptoms in the emergency department (ED). METHODS: This randomized, double-blinded study compared the effectiveness of 50 mg ranitidine (Ulcuran(®)) and 40 mg pantoprazole (Pantpas(®)), given in a 100 mL saline solution by an intravenous rapid infusion within 2-4 minutes in patients with dyspepsia presented to the ED. Pain intensity was measured at baseline, 30 and 60 minutes after the drug administration. RESULTS: A total of 72 patients were eligible for the study. Of these patients, 2 were excluded from the study because the initial visual analogue scale (VAS) scores were under 20 mm and 4 were excluded from the statistical analysis because of being diagnosed as having other causes of epigastric pain despite being allocated to one of the study groups. Thirty-three patients in the pantoprazole group and 33 patients in the ranitidine group were analyzed ultimately. The mean age of the patients was 36.6±15 years, and 26 (39.4%) patients were male. Both of the groups reduced pain effectively at 30 [27.6±28 (18 to 37) vs. 28.3±23 (20 to 37), respectively] and 60 minutes [39.6±39 (26 to 53) vs. 42.3±25 (33 to 51), respectively]. There were 13 (39.4%) patients in the pantoprazole group and 8 (24.2%) patients in the ranitidine group who required additional drug at the end of the study (P=0.186). CONCLUSION: Intravenous pantoprazole and ranitidine are not superior to each other in ceasing dyspeptic symptoms at 30 and 60 minutes in the ED.

Personnel response during an internal emergency-unexpected release of an irritant gas in a hospital.

Internal emergencies can occur at any time and location in a hospital. Planning, training, and exercises can prepare personnel to respond effectively to internal emergency situations. All hospital staff should be trained to recognize an internal incident and activate the hospital emergency management system. Maintaining the health and safety of patients, employees, and visitors is paramount. Training and exercises also encourage staff to act with competence and confidence during an untoward incident to mitigate or avert possible catastrophe. This article describes an incident in which 12 hospital employees presented to the emergency department after exposure to a potent pulmonary irritant gas, chlorine, following an unfortunate accident. These cases are used to illustrate how planning, training, and exercises assisted health care personnel in responding to a potentially catastrophic internal emergency.

Fire-eater's pneumonia: two case reports of accidentally aspirated paraffin oil.

BACKGROUND: Fire-eater's pneumonia is a chemical pneumonitis that can develop after accidental aspiration of liquid hydrocarbon-based fuel during a flame-blowing or a fire-eating performance. Typical findings of the patient are similar with any infectious pneumonia: chest pain, shortness of breath, cough, fever, and hemoptysis can be seen. CASE REPORTS: We report two cases of acute paraffin oil-induced pneumonia due to accidental aspiration during fire-eating performance. CONCLUSION: The symptoms and course of respiratory manifestations and the treatment strategies of fire-eater's pneumonia are reviewed.

Superficial temporal artery pseudoaneurysm: ultrasonographic diagnosis in the ED.

Superficial temporal artery pseudoaneurysm (STAP) is an uncommon complication of blunt and penetrating trauma. It accounts for only 1% of all traumatic aneurysms. Superficial temporal artery pseudoaneurysm usually has the characteristic appearance of a cystic pulsatile mass in the region of the superficial temporal artery. Here we present a case of posttraumatic STAP detected by US in the emergency department (ED). A 58-year-old woman presented to our ED with a tender right frontoparietal mass. Two weeks before presentation, the patient was involved in a motor vehicle accident (MVA) and was taken to the state hospital where the result of a computed tomography scan of the head was shown to be normal except for right frontoparietal soft tissue swelling and hematoma formation. A few days after discharge, the diameter of the soft tissue swelling decreased and the patient was well.However, 2 weeks after the MVA, the patient presented to our ED with a throbbing headache and dramatic increase in the diameter of the lesion. Examination showed a 5 x 5-cm swelling, which was soft, tender, and fluctuant on palpation. The swelling was not pulsatile. Ultrasound was performed using a 7.5-MHz probe and demonstrated a well-defined, pulsatile, anechoic mass measuring approximately 50 x 50 mm in diameter. Ultrasound is a valuable and readily available tool in the ED to confirm the diagnosis.