Liver Abscess Due to Migrated Foreign Body.

Liver abscess secondary to a migrated foreign body (fish bone) is a rare entity where early diagnosis helps in management and thereby improves the prognosis. We present a unique case of a 47-year-old hypertensive man who presented with high-grade fever, chills, rigors, and abdominal pain. On evaluation, he was found to have a liver abscess secondary to a foreign body (fish bone), although no history of foreign body ingestion was recalled by the patient. Drainage of liver abscess and removal of the foreign body comprise the treatment of choice. We report the successful management of a patient with liver abscess from a migrated fish bone. This case underscores the importance of considering foreign body ingestion as a potential cause of liver abscess, even when patients cannot recall such an event. Timely diagnosis and intervention, along with advances in imaging techniques, contribute to successful outcomes in these rare but challenging cases.

Post-COVID-19 cholangiopathy: Current understanding and management options.

Post-coronavirus disease 2019 (COVID-19) cholangiopathy (PCC) is a rare but life-threatening complication of COVID-19 infection. PCC typically presents when patients recovering from the contagion and manifests as cholestasis in patients with no history of pre-existing liver disease. The pathogenesis of PCC is little understood. Hepatic injury in PCC could be mediated by the predilection of severe acute respiratory syndrome coronavirus 2 for cholangiocytes. Though PCC shows some resemblance to secondary sclerosing cholangitis in critically ill patients, it is considered as a separate and unique entity in the literature. Various treatment options like ursodeoxycholic acid, steroids, plasmapheresis, and endoscopic retrograde cholangiopancreatography guided interventions have been tried but with limited success. We have noticed significant improvement in liver function with antiplatelet therapy in a couple of patients. PCC can progress to end-stage liver disease necessitating liver transplantation. In this article, we discuss the current knowledge of PCC focusing on its pathophysiology, clinical manifestations, and management strategies.