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1.
Rev Sci Instrum ; 91(4): 044102, 2020 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-32357719

RESUMO

Optimal wheel alignment improves fuel efficiency, safety, and driver comfort. An explicit formula for determining kingpin parameters, namely, caster and kingpin inclination angle (KIA), in four-wheel alignment is lacking. Currently, caster and KIA values are estimated by repetitive large-scale computing with a mathematical model aimed at obtaining values infinitely close to real solutions. In this study, a four-wheel aligner calibration device was used to collect large amounts of data for a variety of four-wheel aligner measurements with a short data interval. The data were subjected to the local fractal dimension analysis with fractional dimension-based blanket technology (BT) to optimize the number of measurement points. Dramatic changes in data were attributable to local areas with a large fractional number dimension. Appropriate increase in the number of calibration measuring points in areas with a relatively low fractional number dimension can reduce the overall quantity of measuring points. The results provide a scientific basis for the development of alignment calibration standards and demonstrate that these parameters can be assessed based on a small number of measurements. Our BT-based methodology can facilitate factory inspection and performance testing of four-wheel aligners and may improve the accuracy of wheel positioning parameter assessments.

2.
Pak J Pharm Sci ; 30(5(Special)): 1883-1888, 2017 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29084661

RESUMO

Molecular targeted antitumor drugs is a major progress in recent years, these drugs usually target specific molecules to tumor cell signaling pathways, reduce toxicity, and can achieve individualized treatment. In this study, we screened three polypeptide proteins by yeast two hybrid systems, which could inhibit tumor growth obviously. The results of this study are expected to further develop new antitumor drugs. Moreover, by using contrast-enhanced computed tomography (CECT) imaging, this study proposes an algorithm for the computer-aided diagnosis (CAD) and classification of adrenal tumors. The experimental results demonstrate an excellent classification performance of this algorithm. Therefore, the method proposed in this paper may accurately locate and qualitatively diagnose the adrenal tumor in an effective manner, thereby providing important references for treatment.


Assuntos
Neoplasias das Glândulas Suprarrenais/classificação , Neoplasias das Glândulas Suprarrenais/diagnóstico , Terapia de Alvo Molecular/métodos , Peptídeos/farmacologia , Proteínas Quinases Associadas a Fase S/efeitos dos fármacos , Tomografia Computadorizada por Raios X/métodos , Algoritmos , Linhagem Celular Tumoral , Proliferação de Células/efeitos dos fármacos , Diagnóstico por Computador/métodos , Humanos , Peptídeos/síntese química
3.
Pak J Pharm Sci ; 30(3(Special)): 1165-1171, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28671101

RESUMO

This paper based on the theory of radiopharmaceuticals and the theory of radiation risk prediction, the author mainly studies the dose distribution of F-FDG and its radiation risk. Through the assessment of the risk of radiation carcinogenesis, the effective dose range was 4.61mSv to 8.97mSv, and the range of radiation carcinogenic risk was 1.57 ×10-3-3.14×10-3. Also, we reviewed the development trend of medical image processing techniques, and the development of medical imaging processing in three-dimensional (3D) medical imaging visualization and PACS-based medical imaging compression is introduced.


Assuntos
Carcinogênese/efeitos da radiação , Diagnóstico por Imagem/métodos , Fluordesoxiglucose F18/efeitos adversos , Processamento de Imagem Assistida por Computador/métodos , Neoplasias Pulmonares/diagnóstico por imagem , Doses de Radiação , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Fluordesoxiglucose F18/farmacocinética , Humanos , Masculino , Pessoa de Meia-Idade , Compostos Radiofarmacêuticos/farmacocinética , Compostos Radiofarmacêuticos/toxicidade , Distribuição Tecidual
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