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Transpl Infect Dis ; 22(3): e13298, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32306488

RESUMO

Hyperammonemia syndrome, with high levels of ammonia and neurologic dysfunction, is a syndrome with historically high mortality that may occur after solid organ transplantation. Recently, this has been associated with infection due to Ureaplasma, mostly following lung transplantation. We describe the first case of hyperammonemia syndrome due to Ureaplasma infection after liver-kidney transplantation. Our patient rapidly recovered after specific antibiotic treatment. It is important to consider these infections in the differential diagnosis for encephalopathy post-transplant, as these organisms often do not grow using routine culture methods and polymerase chain reaction testing is typically required for their detection. This is particularly critical after liver transplantation, where a number of other etiologies may be considered as a cause of hyperammonemia syndrome.


Assuntos
Hiperamonemia/microbiologia , Transplante de Rim/efeitos adversos , Transplante de Fígado/efeitos adversos , Infecções por Ureaplasma/complicações , Infecções por Ureaplasma/diagnóstico , Antibacterianos/uso terapêutico , Feminino , Humanos , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Resultado do Tratamento , Ureaplasma , Infecções por Ureaplasma/tratamento farmacológico
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