RESUMO
Cogan's syndrome is a rare disorder characterized by the coexistence of ocular and audio-vestibular manifestations. Systemic manifestations are quite unusual with pan-vasculitis and cardiac involvement reported in the form of aortitis with aortic aneurysm, dissection, or extremely rare aortic valve perforation. Hereby, we report a case of a 56-year-old woman presented with ocular, audio-vestibular, and systemic manifestations with medium-sized vasculitis in the form of multiple splenic artery aneurysms, superior mesenteric artery thrombosis, and cardiovascular involvement in the form of aortic regurgitation due to noncoronary cusp perforation. To the best of our knowledge, this is the second case to report aortic perforation in the setting of Cogan's syndrome.
Assuntos
Insuficiência da Valva Aórtica/etiologia , Valva Aórtica , Síndrome de Cogan/complicações , Ruptura Cardíaca/complicações , Insuficiência da Valva Aórtica/diagnóstico , Síndrome de Cogan/diagnóstico , Diagnóstico Diferencial , Ecocardiografia , Feminino , Seguimentos , Ruptura Cardíaca/diagnóstico , Humanos , Pessoa de Meia-Idade , Tomografia Computadorizada por Raios XRESUMO
Unguarded tricuspid orifice is the most extreme of tricuspid valve dysplasia with a very variable natural history. They can tolerate tricuspid regurgitation well, and they become symptomatic only if significant right ventricular dysfunction or atrial fibrillation occurs. Patients with a mild degree of right ventricular dysfunction can survive to adulthood and even reach old age. Surgical treatment is a difficult option due to variable natural history, and surgical results are not too encouraging.
Assuntos
Ecocardiografia , Achados Incidentais , Valva Tricúspide/anormalidades , Valva Tricúspide/diagnóstico por imagem , Adulto , Anticoagulantes/uso terapêutico , Diuréticos/uso terapêutico , Ecocardiografia Tridimensional , Humanos , MasculinoAssuntos
Insuficiência Cardíaca/complicações , Insuficiência Cardíaca/diagnóstico por imagem , Hipertensão Pulmonar/complicações , Hipertensão Pulmonar/diagnóstico por imagem , Mediastinite/complicações , Mediastinite/diagnóstico por imagem , Esclerose/complicações , Esclerose/diagnóstico por imagem , Adulto , Feminino , HumanosRESUMO
Carney complex is a rare autosomal dominant disorder characterized by multiple tumors, including cardiac and extracardiac myxomas, skin lesions, and various endocrine disorders. We are reporting a 21-year-old female patient with past surgical history significant for excision of a cutaneous myxoma who presented with multicentric cardiac myxomas involving the four cardiac chambers. She also presented with endocrinal disorders in the form of an enlarged right lobe of the thyroid, hyperthyroid state, and an incidentally noted adrenal cyst; hence, she was diagnosed with carney complex syndrome.