Treatment of Cesarean Scar Pregnancy with Traditional Chinese Medicine and Warming Moxibustion.

We aimed to report the clinical characteristics of cesarean scar pregnancy (CSP), improve the understanding of uterine scar pregnancy, and assess the outcomes of our treatment strategy for CSP. We present 30 patients with CSP diagnosed by transvaginal ultrasonography. Patients received B ultrasound-guided lauromacrogol injection, followed by evacuation under B ultrasound guidance, and intrauterine balloon compression for hemostasis. Postoperatively, all patients received Bushenquyu decoction and warming moxibustion. All patients showed fast recovery and preserved fertility. The combination of lauromacrogol injection and suction curettage under hysteroscopic guidance is an effective conservative treatment for CSP that can help preserve the reproductive function. Postoperative traditional Chinese medicine and warming moxibustion may reduce the risk of ectopic pregnancy and increase the rate of subsequent intrauterine pregnancy.

[The significance of serum peptidylarginine deiminase 4 in rheumatoid arthritis].

OBJECTIVE: To detect the levels of serum peptidylarginine deiminase (PADI)4 and explore its significance in rheumatoid arthritis (RA). METHODS: The presence of PADI4, anti-PADI4 antibodies and anti-cyclic citrullinated peptide (CCP) antibodies levels were examined by enzyme-linked immunosorbent assay (ELISA). Serum samples were obtained from 100 patients with RA, 23 patients with other rheumatic diseases, and 24 healthy controls. The associations between PADI4 and the disease activity score using 28 joint counts (DAS28) score, anti-CCP antibodies, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), PADI4-94 (rs 2240340) and PADI-104 (rs 1748033) gene polymorphisms and other indexes were analyzed in RA. RESULTS: The levels of PADI4 in RA patients were significantly higher than in other rheumatic diseases and healthy controls (F = 8.75, P < 0.001). There was no significantly difference in levels of PADI4 among ADI4-94 (rs 2240340)/PADI-104 (rs 1748033) genotypes. CONCLUSIONS: PADI4 is associated with disease activity involved in the RA pathogenesis and may be a RA pathogenic antigen.