[The specific and nonspecific mechanisms of the formation of adaptive-compensatory reactions during extreme exposure to heat]. / Spetsificheskie i nespetsificheskie mekhanizmy formirovaniia adaptatsionno-kompensatornykh reaktsii pri ékstremal'nom vozdeistvii tepla.

A total of 250 white male rats were subjected to 48 hours experiment in order to study specific (functional state of thermoregulation, heart muscle, brain cortex) and nonspecific (ration of free radical oxidation activity to antioxidant system activity) mechanisms of adaptational and compensatory reactions, those of alteration and restoration after single critical heating (temperature 41.5 +/- 0.5 degrees C) during 1 hour. The animals appeared to develop no adaptation to the studied heating level, that was demonstrated by assessment of specific regulatory systems and by studies of free radical oxidation and antioxidant system activities.

[The effect of a heat-producing industrial microclimate on the rate of biological aging of the body]. / Vliianie nagrevaiushchego proizvodstvennogo mikroklimata na tempy biologicheskogo stareniia organizma.

While detecting the biological and cardiopulmonary age the authors have demonstrated that the long-term work under the conditions of the heating industrial microclimate promotes acceleration of biological body aging. In the intensification of the aging process, of great importance is the time at which one starts working under the heating microclimate conditions. Based on the data obtained the conclusion is drawn that employment of the persons over 40 years may be restricted in relation to so-called "hot" occupations.

[Body function and the biological aging of those working under the conditions of a warming microclimate]. / Funktsional'noe sostoianie organizma i biologicheskoe starenie rabotaiushchikh v usloviiakh nagrevaiushchego mikroklimata.

The state of the cardiovascular system, indices of thermoregulation, immunological reactivity, cardiopulmonary and biological age were investigated in workers of "hot" professions. It was established that persons working in conditions of heating microclimate show a weakening of the compensation capacities of the cardio-vascular system manifested in a reduction of tone of arterial vessels, inhibition of immunological reactivity. These workers revealed an increased rate of aging of the body at working length over 15 years.

[Results of studies on long-term results of the effects of hot microclimate on the body of workers]. / Nekotorye rezul'taty issledovanii otdalennykh éffektov vozdeistviia nagrevaiushchego mikroklimata na organism rabotaiushchikh.

The article presents data on the functional features of thermoregulation, cardiovascular and respiratory system, neuro-muscular and immune state in those engaged in heating microclimate labour conditions. It is proposed that intensive heat and physical overload results in presenilation among workers, which is proved by changes in their cardiopulmonary and biologic aging processes.