[Arbidol used in the prophylaxis of acute respiratory viral infections and their complications in servicemen]. / Profilaktika arbidolom ostrykh respiratornykh virusnykh infektsii i ikh oslozhnenii u voennosluzhashchikh.

The prophylactic action of arbidol to prevent the acute respiratory viral infections and their complications (extra-hospital pneumonia) was studied under conditions of two military collectives during winter and summer time. The data obtained confirm the prophylactic activity of the drug in respect of ARVI. Regardless of the degree of disease epidemic rise among the servicemen who didn't take arbitol the minimal threshold of grippe and other ARVI incidence (10-15%) remained in the experimental group. The incidence of pneumonia decreased. It was connected with decrease in viral-and-bacterial pneumonia. The number of patients with bacterial (generally pneumococcal) pneumonia didn't change.

[Efficacy of arbidol in prophylaxis and treatment of acute respiratory viral infections in servicemen]. / Effektivnost' arbidola v profilaktike i lechenii ostrykh respiratornykh virusnykh infektsii u voennosluzhashchikh.

The authors present the results of study of arbidolum therapeutic-and-prophylactic effectiveness in acute respiratory viral infections (ARVI) under conditions of military staff with determination of economic expediency. Coefficient of effectiveness of arbidolum prophylactic use was 25% and efficiency index--1.33. In experimental group the ARVI complicated forms were noted in 3% of the patients and in control group--in 5%. Due to decreased expenses on the treatment of non-complicated and complicated ARVI forms the cost of therapy of one servicemen in the first group was 290.6 rubles, in the second group--323 rubles, in the third group--336 rubles and in the fourth group--368 rubles. The results of investigation have shown the significant advantage of arbidolum therapeutic-and-prophylactic use compared with other variants. Its use permitted to decrease the febrile period, to reduce the manifestation of symptoms of intoxication and affection of upper respiratory tract.

[Epidemiologic effectivness of poludane in preventing influenza and other acute respiratory diseases in troops]. / Epidemiologicheskaia éffektivnost' poludana v profilaktike grippa i drugikh ostrykh respiratornykh zabolevani v voiskakh.

The epidemiological effectiveness of interferon inductor "Poludanum" produced by "LENS Pharm" (Russia) for prevention of acute respiratory viral infections was tested. The drug was administered among the students of Military Medical Academy (101 students) according to scheme 1: in a nose, 3 drops in each nasal passage two times per week during 4 weeks, with 2 week interruption then the scheme was repeated. The scheme 2 included 3 drops in each nasal passage once a week during 10 weeks (95 students). The placebo group (96 students) received the distilled water. In the students receiving "Poludanum" according to scheme 1 the incidence of acute respiratory diseases (ARD) was significantly lower than in the control group (p = 0.058). The coefficient of effectiveness was 50%, i.e. the incidence has decreased in two times. The use of poludanum according to scheme 2 caused no decrease in ARD incidence.

[Experience in studying antigenic activity of inactivated hepatitis A vaccine]. / Opyt izucheniia antigennoi aktivnosti inaktivirovannykh vaktsin protiv gepatita A.

The results obtained during the study of antigeneity of inactivated vaccines against hepatitis A ("Avaxim", France; "Hep-A-in-VAC", Russia; "Havrix", Belgium) used in troop units and RF MD institutions are presented in the article. The aim of the investigation is choice of the drug that provides the production of antibody protective levels in maximally short periods. It is very important for the army collectives sent to the zones of armed conflicts and HAV epidemic centres. It is shown that the most acceptable vaccine is "Avaxim" that provides the highest percentage of seroconversion (93.75%) with antibody level not less than 125 mIU/ml. It is recommended to consider this level as the protective one in conditions of army collectives.

[An improvement in the demonstration of the causative agents of dangerous infections under the conditions of local wars and armed conflicts]. / Sovershenstvovanie indikatsii vozbuditelei opasnykh infektsionnykh boleznei v usloviiakh lokal'nykh voin i vooruzhennykh konfliktov.

The system of the specific indication of the causative agents of infectious diseases, accepted in the Armed Forces of the Russian Federation (RF) in piece and wartime and based on the study of specimens by stages in laboratories of the sanitary epidemiological institutions of the Ministry of Defense of the RF, is presented. This system is insufficiently adapted to the conditions of local wars (LW) and armed conflicts (AC). Under these conditions, it is expedient to carry out the specific indication of infective agents not by stages, but completely (according to an enlarged scheme), replenishing the medical service of the field forces with specialists, transferred from higher sanitary epidemiological institutions. Specialized formations of the sanitary epidemiological institutions of the Center should be deployed neat the region of LW or AC, or the specimens should be promptly brought to the Center for indication by air. The improvement of the system of indication includes the introduction of new indication methods, such as polymerase chain reaction, into practical work and cooperation with the institutions and formations of the Ministry of Health of the RF.