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1.
Nutr Metab Cardiovasc Dis ; 28(10): 987-1001, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30143408

RESUMO

AIM: We examined the association between diet quality and diabetes and major cardiometabolic risks among adults in China. METHODS AND RESULTS: We developed the China Dietary Guideline Index (CDGI) based on the 2007 Chinese dietary guidelines and tailored the Alternate Healthy Eating Index 2010 (which we call the tAHEI) to assess diet quality. Our analysis linked the dietary intake and covariates measured in 2006 with CM risk factors measured in 2009. We used diet data the longitudinal China Health and Nutrition Survey 2006 collected in 3 consecutive 24-h recalls from 4440 adults aged 18 to 65 to calculate both the tAHEI and the CDGI scores. We performed multivariable logistic regressions to analyze the association of each 2006 score with diabetes, abdominal obesity, elevated blood pressure, and lipid-related cardiometabolic risk factors in 2009. After we adjusted for potential confounders, adults in the top quintile compared with the bottom quintile of the tAHEI scores showed 36% lower odds of high low-density lipoprotein cholesterol (LDL-C) (odds ratio [OR] 0.64; 95% confidence interval [CI] 0.46, 0.90] in men and 33% lower odds (OR 0.67; 95% CI 0.49, 0.91) in women, while the CDGI scores showed 35% lower odds of high LDL-C (OR 0.65; 95% CI 0.46, 0.92) in men only. Further, the CDGI scores indicated 55% lower odds of diabetes in the top versus the bottom quintile (OR 0.45; 95% CI 0.23, 0.87) in men only, whereas a null association was observed for the tAHEI scores for both sexes. Both index scores showed null associations with other cardiometabolic risk factors. CONCLUSIONS: Chinese diets that scored high on both the CDGI and the tAHEI showed similarly negative associations with high LDL-C risk, whereas only CDGI score was negatively related to diabetes risk in men.


Assuntos
Diabetes Mellitus Tipo 2/epidemiologia , Dieta Saudável , Dieta , Síndrome Metabólica/epidemiologia , Valor Nutritivo , Adolescente , Adulto , Idoso , Biomarcadores/sangue , Pressão Sanguínea , China , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/fisiopatologia , Diabetes Mellitus Tipo 2/prevenção & controle , Dieta/efeitos adversos , Dislipidemias/sangue , Dislipidemias/epidemiologia , Feminino , Humanos , Hipertensão/diagnóstico , Hipertensão/fisiopatologia , Lipídeos/sangue , Masculino , Síndrome Metabólica/sangue , Síndrome Metabólica/fisiopatologia , Síndrome Metabólica/prevenção & controle , Pessoa de Meia-Idade , Inquéritos Nutricionais , Obesidade Abdominal/epidemiologia , Estudos Prospectivos , Fatores de Proteção , Recomendações Nutricionais , Medição de Risco , Fatores de Risco , Fatores Sexuais , Adulto Jovem
2.
BJOG ; 125(7): 895-903, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28886230

RESUMO

OBJECTIVE: To estimate the association between lipoprotein particle concentrations in pregnancy and gestational age at delivery. DESIGN: Prospective cohort study. SETTING: The study was conducted in the USA at the University of North Carolina. POPULATION: We assessed 715 women enrolled in the Pregnancy, Infection, and Nutrition study from 2001 to 2005. METHODS: Fasting blood was collected at two time points (<20 and 24-29 weeks of gestation). Nuclear magnetic resonance (NMR) quantified lipoprotein particle concentrations [low-density lipoprotein (LDL), high-density lipoprotein (HDL), very-low density lipoprotein (VLDL)] and 10 subclasses of lipoproteins. Concentrations were assessed as continuous measures, with the exception of medium HDL which was classified as any or no detectable level, given its distribution. Cox proportional hazards models estimated hazard ratios (HR) for gestational age at delivery adjusting for covariates. MAIN OUTCOME MEASURES: Gestational age at delivery, preterm birth (<37 weeks of gestation), and spontaneous preterm birth. RESULTS: At <20 weeks of gestation, three lipoproteins were associated with later gestational ages at delivery [large LDLNMR (HR 0.78, 95% CI 0.64-0.96), total VLDLNMR (HR 0.77, 95% CI 0.61-0.98), and small VLDLNMR (HR 0.78, 95% CI 0.62-0.98], whereas large VLDLNMR (HR 1.19, 95% CI 1.01-1.41) was associated with a greater hazard of earlier delivery. At 24-28 weeks of gestation, average VLDLNMR (HR 1.25, 95% CI 1.03-1.51) and a detectable level of medium HDLNMR (HR 1.90, 95% CI 1.19-3.02) were associated with earlier gestational ages at delivery. CONCLUSION: In this sample of pregnant women, particle concentrations of VLDLNMR , LDLNMR , IDLNMR , and HDLNMR were each independently associated with gestational age at delivery for all deliveries or spontaneous deliveries <37 weeks of gestation. These findings may help formulate hypotheses for future studies of the complex relationship between maternal lipoproteins and preterm birth. TWEETABLE ABSTRACT: Nuclear magnetic resonance spectroscopy may identify lipoprotein particles associated with preterm delivery.


Assuntos
Trabalho de Parto/sangue , Lipoproteínas/sangue , Espectroscopia de Ressonância Magnética/métodos , Testes para Triagem do Soro Materno/métodos , Nascimento Prematuro/sangue , Adulto , Parto Obstétrico , Jejum/sangue , Feminino , Idade Gestacional , Humanos , Lipoproteínas HDL/sangue , Lipoproteínas LDL/sangue , Lipoproteínas VLDL/sangue , Gravidez , Modelos de Riscos Proporcionais , Estudos Prospectivos
5.
J Hum Hypertens ; 31(7): 462-473, 2017 07.
Artigo em Inglês | MEDLINE | ID: mdl-28205551

RESUMO

Measurement error in assessment of sodium and potassium intake obscures associations with health outcomes. The level of this error in a diverse US Hispanic/Latino population is unknown. We investigated the measurement error in self-reported dietary intake of sodium and potassium and examined differences by background (Central American, Cuban, Dominican, Mexican, Puerto Rican and South American). In 2010-2012, we studied 447 participants aged 18-74 years from four communities (Miami, Bronx, Chicago and San Diego), obtaining objective 24-h urinary sodium and potassium excretion measures. Self-report was captured from two interviewer-administered 24-h dietary recalls. Twenty percent of the sample repeated the study. We examined bias in self-reported sodium and potassium from diet and the association of mismeasurement with participant characteristics. Linear regression relating self-report with objective measures was used to develop calibration equations. Self-report underestimated sodium intake by 19.8% and 20.8% and potassium intake by 1.3% and 4.6% in men and women, respectively. Sodium intake underestimation varied by Hispanic/Latino background (P<0.05) and was associated with higher body mass index (BMI). Potassium intake underestimation was associated with higher BMI, lower restaurant score (indicating lower consumption of foods prepared away from home and/or eaten outside the home) and supplement use. The R2 was 19.7% and 25.0% for the sodium and potassium calibration models, respectively, increasing to 59.5 and 61.7% after adjusting for within-person variability in each biomarker. These calibration equations, corrected for subject-specific reporting error, have the potential to reduce bias in diet-disease associations within this largest cohort of Hispanics in the United States.


Assuntos
Potássio na Dieta/urina , Autorrelato , Sódio na Dieta/urina , Adulto , Idoso , Biomarcadores/urina , Calibragem , Estudos de Coortes , Feminino , Hispânico ou Latino/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
6.
Lupus ; 26(6): 623-632, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-27703053

RESUMO

Objective The objective of this study was to estimate the proportion of pregnant women with systemic lupus erythematosus meeting Institute of Medicine guidelines for gestational weight gain and determine correlates of adherence to guidelines. Methods Singleton, live births in the Hopkins Lupus Pregnancy Cohort 1987-2015 were included. Pre-pregnancy weight was the weight recorded 12 months prior to pregnancy/first trimester. Final weight was the last weight recorded in the third trimester. Adherence to Institute of Medicine guidelines (inadequate, adequate, or excessive) was based on pre-pregnancy body mass index. Fisher's exact test and analysis of variance determined factors associated with not meeting guidelines. Stepwise selection estimated predictors of gestational weight gain. Results Of the 211 pregnancies, 34%, 24% and 42% had inadequate, adequate and excessive gestational weight gain, respectively. In exploratory analyses, differences in Institute of Medicine adherence were observed by pre-pregnancy body mass index, race, elevated creatinine during pregnancy and pre-pregnancy blood pressure. Odds of inadequate and excessive gestational weight gain increased 12% with each 1 kg/m2 increase in pre-pregnancy body mass index. Lower maternal education was associated with increased odds of inadequate and excessive gestational weight gain. Conclusions As in the general population, most women with systemic lupus erythematosus did not meet Institute of Medicine guidelines. Our results identified predictors of gestational weight gain to aid in targeted interventions to improve guideline adherence in this population.


Assuntos
Lúpus Eritematoso Sistêmico/complicações , Obesidade/epidemiologia , Complicações na Gravidez/epidemiologia , Adulto , Índice de Massa Corporal , Feminino , Humanos , Guias de Prática Clínica como Assunto , Gravidez , Terceiro Trimestre da Gravidez , Aumento de Peso
7.
Eur J Clin Nutr ; 71(4): 486-493, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-27677363

RESUMO

BACKGROUND/OBJECTIVES: This study investigates secular trends in diet quality distribution and related socioeconomic disparity from 1991 to 2011 in the Chinese adult population. SUBJECTS/METHODS: The analysis uses the 1991-2011 China Health and Nutrition Survey data on 13 853 participants (6876 men and 6977 women) aged 18-65 with 56 319 responses. Dietary assessment was carried out over a 3-day period with 24-h recalls combined with a household food inventory. We tailored Alternative Healthy Eating Index 2010 (named as tAHEI) to measure diet quality and performed quantile regression to investigate shifts in tAHEI scores at different percentiles and used mixed-effect linear regression to examine average diet quality trend and potential sociodemographic disparity. RESULTS: The energy-adjusted mean tAHEI scores increased from 36.9 (36.7-37.1) points in 1991 to 50.3 (50.1-50.5) in 2011 for men (P<0.001) and from 35.6 (35.4-35.8) to 46.9 (46.7-47.1) for women (P<0.001). The covariate-adjusted score of polyunsaturated fatty acids increased by 6.8 (6.6, 7.0) and 7.0 (6.9, 7.2), and the score of long-chain (ω-3) fats increased by 5.3 (5.2, 5.4) and 5.3 (5.2, 5.5) in men and women, respectively, whereas the cereal fiber and red meat scores decreased slightly. Increasing tAHEI score occurred across the entire distribution, and diet quality transition varied across sociodemographic groups. CONCLUSIONS: Chinese diet quality is far from optimal, with moderate improvement over a 21-year period. Findings suggest that nutritional intervention should give priority to low-income, low-urbanized communities and southern provincial adults with low diet quality in China.


Assuntos
Povo Asiático/estatística & dados numéricos , Dieta/tendências , Disparidades nos Níveis de Saúde , Adolescente , Adulto , Idoso , China , Dieta/normas , Registros de Dieta , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Inquéritos Nutricionais , Estado Nutricional , Valor Nutritivo , Análise de Regressão , Fatores Socioeconômicos , Adulto Jovem
8.
Public Health Nutr ; 19(18): 3256-3264, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-27339078

RESUMO

OBJECTIVE: Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake. DESIGN: The Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants' diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants. SETTING: Four centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA. SUBJECTS: Men and women (n 477) aged 18-74 years. RESULTS: The geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=-0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake. CONCLUSIONS: Possible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.


Assuntos
Inquéritos sobre Dietas , Sacarose Alimentar/administração & dosagem , Hispânico ou Latino , Açúcares/administração & dosagem , Adolescente , Adulto , Idoso , Biomarcadores/urina , Sacarose Alimentar/urina , Ingestão de Energia , Feminino , Frutose/urina , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Autorrelato , Estados Unidos , Adulto Jovem
9.
Int J Obes (Lond) ; 40(7): 1056-62, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-27133623

RESUMO

BACKGROUND/OBJECTIVES: Poor maternal diet in pregnancy can influence fetal growth and development. We tested the hypothesis that poor maternal diet quality during pregnancy would increase neonatal adiposity (percent fat mass (%FM)) at birth by increasing the fat mass (FM) component of neonatal body composition. METHODS: Our analysis was conducted using a prebirth observational cohort of 1079 mother-offspring pairs. Pregnancy diet was assessed via repeated Automated Self-Administered 24-h dietary recalls, from which Healthy Eating Index-2010 (HEI-2010) scores were calculated for each mother. HEI-2010 was dichotomized into scores of ⩽57 and >57, with low scores representing poorer diet quality. Neonatal %FM was assessed within 72 h after birth with air displacement plethysmography. Using univariate and multivariate linear models, we analyzed the relationship between maternal diet quality and neonatal %FM, FM, and fat-free mass (FFM) while adjusting for prepregnancy body mass index (BMI), physical activity, maternal age, smoking, energy intake, preeclampsia, hypertension, infant sex and gestational age. RESULTS: Total HEI-2010 score ranged between 18.2 and 89.5 (mean: 54.2, s.d.: 13.6). An HEI-2010 score of ⩽57 was significantly associated with higher neonatal %FM (ß=0.58, 95% confidence interval (CI) 0.07-1.1, P<0.05) and FM (ß=20.74; 95% CI 1.49-40.0; P<0.05) but no difference in FFM. CONCLUSIONS: Poor diet quality during pregnancy increases neonatal adiposity independent of maternal prepregnancy BMI and total caloric intake. This further implicates maternal diet as a potentially important exposure for fetal adiposity.


Assuntos
Adiposidade/fisiologia , Fenômenos Fisiológicos da Nutrição Materna , Mães , Adulto , Peso ao Nascer/fisiologia , Glicemia , Índice de Massa Corporal , Dieta , Inquéritos sobre Dietas , Ingestão de Energia , Comportamento Alimentar , Feminino , Desenvolvimento Fetal/fisiologia , Humanos , Recém-Nascido , Estudos Longitudinais , Gravidez , Fenômenos Fisiológicos da Nutrição Pré-Natal , Estados Unidos/epidemiologia
10.
Diabet Med ; 33(5): 663-7, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26872289

RESUMO

AIMS: To examine the association between dysglycaemia and multiple modifiable factors measured during pregnancy. METHODS: The Healthy Start Study collected self-reported data on modifiable factors in early and mid-pregnancy (median 17 and 27 weeks gestation, respectively) from 832 women. Women received one point for each modifiable factor for which they had optimum scores: diet quality (Healthy Eating Index score ≥64), physical activity level (estimated energy expenditure ≥170 metabolic equivalent task-h/week), and mental health status (Perceived Stress Scale score <6 and Edinburgh Postnatal Depression Scale score <13). Dysglycaemia during pregnancy was defined as an abnormal glucose challenge result, ≥1 abnormal results on an oral glucose tolerance test, or a clinical diagnosis of gestational diabetes. Logistic regression models estimated odds ratios for dysglycaemia as a function of each factor and the total score, adjusted for age, race/ethnicity, pre-pregnancy BMI, history of gestational diabetes, and family history of Type 2 diabetes. RESULTS: In individual analyses, only physical activity was significantly associated with a reduced risk of dysglycaemia (adjusted odds ratio 0.67, 95% CI 0.44-1.00). We observed a significant, dose-response association between increasing numbers of optimal factors and odds of dysglycaemia (adjusted P=0.01). Compared with having no optimal modifiable factors, having all three was associated with a 73% reduced risk of dysglycaemia (adjusted odds ratio 0.27, 95% CI 0.08-0.95). CONCLUSIONS: An increasing number of positive modifiable factors in pregnancy was associated with a dose-response reduction in risk of dysglycaemia. Our results support the hypothesis that modifiable factors in pregnancy are associated with the risk of prenatal dysglycaemia.


Assuntos
Dieta Saudável , Exercício Físico , Transtornos do Metabolismo de Glucose/prevenção & controle , Estilo de Vida Saudável , Doenças do Recém-Nascido/prevenção & controle , Saúde Mental , Complicações na Gravidez/prevenção & controle , Adulto , Estudos de Coortes , Colorado/epidemiologia , Feminino , Transtornos do Metabolismo de Glucose/epidemiologia , Humanos , Recém-Nascido , Doenças do Recém-Nascido/epidemiologia , Masculino , Fenômenos Fisiológicos da Nutrição Materna , Gravidez , Complicações na Gravidez/epidemiologia , Estudos Prospectivos , Risco , Autorrelato , Adulto Jovem
11.
BJOG ; 120(9): 1116-22, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23651010

RESUMO

OBJECTIVE: To assess the relationship between unintended pregnancy and postpartum depression. DESIGN: Secondary analysis of data from a prospective pregnancy cohort. SETTING: The study was performed at the University of North Carolina prenatal care clinics. POPULATION/SAMPLE: Pregnant women enrolled for prenatal care at the University of North Carolina Hospital Center. METHODS: Participants were questioned about pregnancy intention at 15-19 weeks of gestation, and classified as having an intended, mistimed or unwanted pregnancy. They were evaluated for postpartum depression at 3 and 12 months postpartum. Log binomial regression was used to assess the relationship between unintended pregnancy and depression, controlling for confounding by demographic factors and reproductive history. MAIN OUTCOME MEASURES: Depression at 3 and 12 months postpartum, defined as Edinburgh Postpartum Depression Scale score >13. RESULTS: Data were analysed for 688 women at 3 months and 550 women at 12 months. Depression was more likely in women with unintended pregnancies at both 3 months (risk ratio [RR] 2.1, 95% confidence interval [95% CI] 1.2-3.6) and 12 months (RR 3.6, 95% CI 1.8-7.1). Using multivariable analysis adjusting for confounding by age, poverty and education level, women with unintended pregnancies were twice as likely to have postpartum depression at 12 months (RR 2.0, 95% CI 0.96-4.0). CONCLUSION: While many elements may contribute to postpartum depression, unintended pregnancy could also be a contributing factor. Women with unintended pregnancy may have an increased risk of depression up to 1 year postpartum.


Assuntos
Depressão Pós-Parto/diagnóstico , Gravidez não Planejada/psicologia , Gravidez não Desejada/psicologia , Adulto , Depressão Pós-Parto/epidemiologia , Feminino , Humanos , Modelos Logísticos , North Carolina/epidemiologia , Gravidez , Cuidado Pré-Natal , Estudos Prospectivos , Medição de Risco , Fatores de Risco , Fatores Socioeconômicos , Inquéritos e Questionários , Fatores de Tempo
12.
Pediatr Obes ; 7(2): 134-42, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22434753

RESUMO

OBJECTIVE: To determine how gestational weight gain (GWG), categorized using the 2009 Institute of Medicine recommendations, relates to changes in offspring weight-for-age (WAZ), length-for-age (LAZ) and weight-for-length z-scores (WLZ) between early infancy and 3 years. METHODS: Women with singleton infants were recruited from the third cohort of the Pregnancy, Infection, and Nutrition Study (2001-2005). Term infants with at least one weight or length measurement during the study period were included (n = 476). Multivariable linear mixed effects regression models estimated longitudinal changes in WAZ, LAZ and WLZ associated with GWG. RESULTS: In early infancy, compared with infants of women with adequate weight gain, those of women with excessive weight gains had higher WAZ, LAZ and WLZ. Excessive GWG ≥ 200% of the recommended amount was associated with faster rates of change in WAZ and LAZ and noticeably higher predicted mean WAZ and WLZ that persisted across the study period. CONCLUSIONS: GWG is associated with significant differences in offspring anthropometrics in early infancy that persisted to 3 years of age. More longitudinal studies that utilize maternal and paediatric body composition measures are necessary to understand the nature of this association.


Assuntos
Antropometria , Desenvolvimento Infantil/fisiologia , Obesidade/epidemiologia , Complicações na Gravidez/epidemiologia , Efeitos Tardios da Exposição Pré-Natal/epidemiologia , Aumento de Peso/fisiologia , Adolescente , Adulto , Pré-Escolar , Estudos de Coortes , Feminino , Humanos , Lactente , Recém-Nascido , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Gravidez , Complicações na Gravidez/fisiopatologia , Efeitos Tardios da Exposição Pré-Natal/fisiopatologia , Medição de Risco/métodos , Fatores de Risco , Adulto Jovem
13.
Am J Epidemiol ; 157(1): 14-24, 2003 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-12505886

RESUMO

This study examined a comprehensive array of psychosocial factors, including life events, social support, depression, pregnancy-related anxiety, perceived discrimination, and neighborhood safety in relation to preterm birth (<37 weeks) in a prospective cohort study of 1,962 pregnant women in central North Carolina between 1996 and 2000, in which 12% delivered preterm. There was an increased risk of preterm birth among women with high counts of pregnancy-related anxiety (risk ratio (RR) = 2.1, 95% confidence interval (CI): 1.5, 3.0), with life events to which the respondent assigned a negative impact weight (RR = 1.8, 95% CI: 1.2, 2.7), and with a perception of racial discrimination (RR = 1.4, 95% CI: 1.0, 2.0). Different levels of social support or depression were not associated with preterm birth. Preterm birth initiated by labor or ruptured membranes was associated with pregnancy-related anxiety among women assigning a high level of negative impact weights (RR = 3.0, 95% CI: 1.7, 5.3). The association between high levels of pregnancy-related anxiety and preterm birth was reduced when restricted to women without medical comorbidities, but the association was not eliminated. The prospective collection of multiple psychosocial measures on a large population of women indicates that a subset of these factors is associated with preterm birth.


Assuntos
Ansiedade/complicações , Trabalho de Parto Prematuro/etiologia , Complicações na Gravidez , Estresse Psicológico/complicações , Adolescente , Adulto , Negro ou Afro-Americano/educação , Negro ou Afro-Americano/psicologia , Negro ou Afro-Americano/estatística & dados numéricos , Ansiedade/epidemiologia , Ansiedade/prevenção & controle , Comorbidade , Feminino , Humanos , Acontecimentos que Mudam a Vida , Estilo de Vida , Mães/educação , Mães/psicologia , Mães/estatística & dados numéricos , Análise Multivariada , North Carolina/epidemiologia , Gravidez , Complicações na Gravidez/prevenção & controle , Preconceito , Estudos Prospectivos , Características de Residência , Fatores de Risco , Apoio Social , Estresse Psicológico/epidemiologia , Estresse Psicológico/prevenção & controle , Inquéritos e Questionários , População Branca/educação , População Branca/psicologia , População Branca/estatística & dados numéricos
15.
Am J Obstet Gynecol ; 185(2): 403-12, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11518900

RESUMO

OBJECTIVE: Fasting during pregnancy stimulates preterm delivery in animals and increases women's risk for preterm delivery. Fasting stimulates hypothalamic corticotropin-releasing hormone production in animals. Elevated maternal corticotropin-releasing hormone concentrations are associated with preterm birth. We hypothesized that prolonged periods without food during pregnancy increase maternal corticotropin-releasing hormone concentrations, which lead to preterm delivery. STUDY DESIGN: In the Behavior in Pregnancy Study, we examined prolonged periods without eating during pregnancy and corticotropin-releasing hormone concentrations and gestational age at delivery with multivariate logistic regression analysis (n = 237). RESULTS: Prolonged periods without food lasting 13 hours or longer were associated with elevated maternal corticotropin-releasing hormone concentrations compared with prolonged periods without food lasting less than 13 hours at two time points during pregnancy, controlling for pregravid body mass index, energy intake, income, race, smoking, and maternal age (18-20 weeks: adjusted odds ratio, 2.5; 95% CI, 0.9-7.1; 28-30 weeks: adjusted odds ratio, 1.7; 95% CI, 0.7-4.2). There was an inverse, linear relationship between maternal corticotropin-releasing hormone concentrations and gestational age at delivery. CONCLUSIONS: Prolonged periods without food intake during pregnancy are associated with elevated maternal corticotropin-releasing hormone concentrations and with preterm delivery.


Assuntos
Hormônio Liberador da Corticotropina/sangue , Jejum/efeitos adversos , Trabalho de Parto Prematuro/etiologia , Adolescente , Adulto , Índice de Massa Corporal , Ingestão de Energia , Exercício Físico , Feminino , Idade Gestacional , Humanos , Renda , Modelos Logísticos , Paridade , Gravidez , Grupos Raciais , Fatores de Risco , Estresse Fisiológico , Fatores de Tempo
16.
Am J Obstet Gynecol ; 185(2): 438-43, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11518906

RESUMO

OBJECTIVE: To determine the prevalence of anemia from 4 to 26 weeks post partum and to examine prenatal predictors of postpartum anemia. STUDY DESIGN: Retrospective cohort analysis of 59,428 participants in the Special Supplemental Nutrition Program for Women, Infants, and Children in 12 US states. RESULTS: The prevalence of postpartum anemia was 27%. Anemia rates were higher among minority women, reaching 48% among non-Hispanic black women. Of 9129 women who had normal hemoglobin in the third trimester, 21% had postpartum anemia. Prenatal anemia was the strongest predictor of postpartum anemia (adjusted odds ratio, 2.7; 95% confidence interval, 2.5-2.8). Maternal obesity, multiple birth, and not breast-feeding also predicted postpartum anemia. CONCLUSION: The high prevalence of post partum anemia among low-income women highlights the importance of anemia screening at 4 to 6 weeks post partum. These data suggest that screening should not be limited, as it is at present, to women considered at high risk.


Assuntos
Anemia/epidemiologia , Pobreza , Transtornos Puerperais/epidemiologia , Adolescente , Adulto , Negro ou Afro-Americano , Asiático , Índice de Massa Corporal , Aleitamento Materno , Criança , Estudos de Coortes , Feminino , Hemoglobinas/análise , Hispânico ou Latino , Humanos , Indígenas Norte-Americanos , Pessoa de Meia-Idade , Grupos Minoritários , Obesidade/complicações , Gravidez , Complicações Hematológicas na Gravidez , Terceiro Trimestre da Gravidez , Gravidez Múltipla , Estudos Retrospectivos , Estados Unidos/epidemiologia
17.
J Am Med Womens Assoc (1972) ; 56(2): 44-8, 72, 2001.
Artigo em Inglês | MEDLINE | ID: mdl-11326795

RESUMO

OBJECTIVE: To identify dietary trends among low socioeconomic status women of childbearing age from three ethnic groups from 1977 to 1996. METHODS: The sample consisted of 19- to 44-year-old women at 185% of poverty with 12 years of education or less (n = 4682) from three US Department of Agriculture surveys. The Revised Diet Quality Index (DQI-R) and level of folate were the main outcomes measured. Changes in food consumption for several food groups were also examined. RESULTS: Diet quality significantly improved between 1977 and 1996 for Hispanics and non-Hispanic whites. All groups had significant decreases in saturated fat intake by 1996, but only Hispanic and non-Hispanic white women significantly decreased their total fat and cholesterol intakes. Fruit and vegetable intakes remained stable. Mean intakes of calcium, iron, and folate were below recommendations at every time point for all ethnic groups. All three groups decreased their intakes of butter, margarine, egg items, bacon, high-fat red meats, and low-fiber/high-fat breads and increased their intakes of high-fiber cereals, all of which are positive. These trends were balanced, however, by decreases in medium-fiber vegetables, soy, and legumes and increases in high-fat/high-fiber breads, high-fat desserts, high-fat salty snacks, and high-fat grain-based mixed dishes. CONCLUSIONS: This study highlights problem dietary habits that public health professionals need to address in order to reduce the prevalence of diet-related chronic diseases.


Assuntos
Dieta/tendências , Etnicidade/estatística & dados numéricos , Pobreza , Saúde da Mulher , Adulto , Negro ou Afro-Americano/estatística & dados numéricos , Feminino , Hispânico ou Latino/estatística & dados numéricos , Humanos , Estados Unidos/etnologia , População Branca/estatística & dados numéricos
18.
Am J Epidemiol ; 153(7): 647-52, 2001 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-11282791

RESUMO

Frequency of eating or meal patterns during pregnancy may be a component of maternal nutrition relevant to pregnancy outcome. To identify meal patterns of pregnant women and investigate the relation between these meal patterns and preterm delivery, the authors performed an analysis using data from the Pregnancy, Infection, and Nutrition Study (n = 2,065). Women recruited from August 1995 to December 1998 were categorized by meal patterns on the basis of their reported number of meals (breakfast, lunch, and dinner) and snacks consumed per day during the second trimester. An optimal pattern was defined according to the Institute of Medicine recommendation of three meals and two or more snacks per day. In this population, 72 percent of the women met this recommendation, and 235 delivered preterm. Women who consumed meals/snacks less frequently were slightly heavier prior to pregnancy, were older, and had a lower total energy intake. In addition, these women had a higher risk of delivering preterm (adjusted odds ratio = 1.30, 95 percent confidence interval: 0.96, 1.76). There was no meaningful difference in the risk by early versus late preterm delivery, but those who delivered after premature rupture of the membranes (adjusted odds ratio = 1.87, 95 percent confidence interval: 1.02, 3.43) had a higher risk than those who delivered after preterm labor (adjusted odds ratio = 1.11, 95 percent confidence interval: 0.64, 1.89). This study supports previous animal model work of an association between decreased frequency of eating and preterm delivery.


Assuntos
Comportamento Alimentar , Recém-Nascido Prematuro , Estado Nutricional , Trabalho de Parto Prematuro/epidemiologia , Trabalho de Parto Prematuro/etiologia , Resultado da Gravidez , Gravidez/fisiologia , Adolescente , Adulto , Estudos de Coortes , Intervalos de Confiança , Feminino , Humanos , Recém-Nascido , North Carolina/epidemiologia , Razão de Chances , Paridade , Estudos Prospectivos , Medição de Risco , Fatores de Risco , Fatores Socioeconômicos
19.
Prev Med ; 32(4): 303-10, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11304090

RESUMO

BACKGROUND: Studies on children and adolescents suggest a large increase in the role of snacking; however, little is know about changes in the snacking behavior of young adults. METHODS: USDA's nationally representative surveys from 1977-1978 to 1994-1996 are used to study snacking trends among 8,493 persons 19-29 years old. RESULTS: Snacking prevalence increased from 77 to 84% between 1977-1978 and 1994-1996. The nutritional contribution of snacks to total daily energy intake went from 20 to 23%, primarily because energy consumed per snacking occasion increased by 26% and the number of snacks per day increased 14%. The mean daily caloric density (calorie per gram of food) of snacks increased from 1.05 to 1.32 calories. The energy contribution of high-fat desserts to the total calories from snacking decreased (22 to 14%), however, this food group remained the most important source of energy. The energy contribution of high-fat salty snacks doubled. Sweetened and alcoholic beverages remained important energy contributors. CONCLUSION: This large increase in total energy and energy density of snacks among young adults in the United States may be contributing to our obesity epidemic.


Assuntos
Comportamento Alimentar , Valor Nutritivo , Adulto , Inquéritos sobre Dietas , Ingestão de Energia , Feminino , Humanos , Modelos Lineares , Masculino , Obesidade/etiologia , Fatores de Tempo
20.
J Pediatr ; 138(4): 493-8, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11295711

RESUMO

OBJECTIVES: To determine snacking trends and changes in nutrient contribution of snacking over time. STUDY DESIGN: Nationally representative data from the 1977-78 Nationwide Food Consumption Survey (NFCS77), 1989-91 Continuing Survey of Food Intake by Individuals (CSFII89), and 1994-96 (CSFII96) were used. The sample consisted of 21,236 individuals aged 2 to 18 years. METHODS: For each survey year, mean numbers of snacks consumed, mean grams consumed per snack, and mean energy intake from snacks were computed, as was contribution of snacking to total energy intake and fat intake. Snacking was self-defined, and a snacking occasion consisted of all snack foods consumed during a 15-minute period. Differences in means between age groups and across survey years were compared. RESULTS: The prevalence of snacking increased in all age groups. The average size of snacks and energy per snack remained relatively constant; however, the number of snacking occasions increased significantly, therefore increasing the average daily energy from snacks. Compared with non-snack eating occasions, the nutrient contribution of snacks decreased in calcium density and increased in energy density and proportion of energy from fat. CONCLUSION: Snacking is extremely prevalent in our society. Healthy snack food choices should be emphasized over high-energy density convenience snacks for children.


Assuntos
Comportamento Alimentar , Adolescente , Distribuição por Idade , Criança , Pré-Escolar , Inquéritos sobre Dietas , Gorduras na Dieta/administração & dosagem , Ingestão de Energia/fisiologia , Comportamento Alimentar/fisiologia , Feminino , Humanos , Masculino , Fatores Socioeconômicos , Estados Unidos
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