Evaluation of the efficiency of hospital antibiotic policy applied Dr Jan Biziel University Hospital No 2 in Bydgoszcz in 2009-2013.

UNLABELLED: The Hospital Infection Control Team (HICT) of Dr Jan Biziel University Hospital No 2 in Bydgoszcz developed and implemented the principles of a rational antibiotic therapy in 2008. A behavior algorithm has worked since 01.10.2008. Implementation of the principles of a rational antibiotic therapy was part of the hospital antibiotic policy. THE AIM OF THE STUDY: is to evaluate either introductory principles of the rational antibiotic therapy, after five-year experience lived up to expectations in the range specified by the authors. MATERIAL AND METHODS: Hospital microbiological maps, comparisons of antibiotic cost, specification of microbiological tests made before and after introduction of the principles of a rational antibiotic therapy have been analyzed. Annual antibiotic consumption has been counted according to the defined daily dose (DDD) index created by the WHO. RESULTS: After 6 years of implementation of the rational antibiotic therapy principles, the decrease in number of isolated strains which are resistant to Klebsiella pneumoniae ESBL and Acinetobacter baumanii (resistant to carbapenems) has been indicated. The number of the Pseudomonas aeruginosa isolates has increased approximately three times, and the number of resistant isolates to carbapenem has grown six times. The cost of antibiotics has been gradually decreased in 2012 in order to represent 9,66% of all drug budget (without drug programs). Detailed analysis of antibiotic consumption has showed that after the implementation of rational antibiotic therapy principles the consumption of meropenem has increased twice in comparison to the all drugs. The number of microbiological tests grew from 0,20 to 0,29 per one patient, which means material to microbiological tests has been taken from every third patient. Annual DDD index calculated on 100 person-days has been reduced from 59,552 in 2007 to 39,90 in 2009, and it is 47,88 in 2013. The principles of rational antibiotic therapy in comparison with the other elements of antibiotic policy in hospital have caused positive changes in antibiotic ordinance. CONCLUSIONS: 1. It is required to adhere to the principles of a rational antibiotic therapy by medical staff mainly on the administrative restriction of access to antibiotics. 2. Monitoring changes in drug resistance of hospital flora is an essential element of the principles of a rational antibiotic therapy modification.

[Practical aspects of implementation quality management system ISO 9001:2000 by hospital infection control team]. / Praktyczne aspekty wdrazania systemu zarzadzania jakoscia ISO 9001:2000 przez Zespól Kontroli Zakazen Szpitalnych.

In 2006 the Board of the Jan Biziel Hospital in Bydgoszcz decided to include procedures of health services in the implementation process within the confines of ISO 9001:2000 certification. The hospital infection control team that has operated in the hospital since 1989 performed the analysis of the forms of activities to date and on that basis the team prepared original plan of quality management. In April 2007, this plan was successfully accepted by the certifying team. The aim of this study is to present the aforementioned plan which is the result of 18 years experience of the team. At the same time, I hope that this study will be very helpful for all professionals interested in hospital epidemiology, especially in the context of implementing quality management systems.

[Evaluation of the coexistence of chlamydia trachomatis symptoms and antispermatozoonal antibodies in sperm of men treated for infertility]. / Ocena wspólistnienia objawów zakazenia chlamydia trachomatis i przeciwcial przeciwplemnikowych w nasieniu mezczyzn leczonych z powodu nieplodnosci.

INTRODUCTION: Marital infertility has become an increasing problem of contemporary medicine. It is acknowledged that the responsibility for this fact is placed in half with the male factor. To a great degree it is caused by existence of male genitals inflammatory processes. AIM: Evaluation of the influence of Chlamydia infection on the level of anti-spermatozoonal antibodies /p.p.p./ in sperm. MATERIAL: Research encompassed 187 men treated at the Regional Andrological Outpatient Clinic and the Clinic for Treating Marital Infertility of Dr. J. Biziel Regional Hospital in Bydgoszcz. RESULTS: Lowering of p.p.p. titre was observed in men treated for Chlamydia Trachomatis infection. Lowering of the p.p.p. level was greater after the first course of treatment. Whereas the subsequent ones were not so distinct. CONCLUSIONS: Treatment of male genitals inflammatory processes influences the lowering of p.p.p. titre in men with decreased fertility. It was confirmed as a results of treating men with Chlamydia Trachomatis infection.