Association Between Smartphone Applications for Pregnant Women and Psychological Distress in Japan.

The current study investigated pregnant women's use of pregnancy applications (apps) and how these apps affect their mental health. A questionnaire was administered in the outpatient obstetrics and gynecology department at a university hospital. Of 110 pregnant women included in the analysis, 97 had downloaded and used pregnancy apps and believed that these were either helpful or a little helpful. Among the 110 respondents, 20 (18.2%) women were identified as having psychological distress. Thus, the percentage of women with psychological distress who downloaded pregnancy apps was significantly lower than women in the mentally healthy group. Non-use of pregnancy apps was strongly associated with psychological distress, indicating that pregnancy apps improve pregnant women's mental health. Alternatively, non-use of apps could arise from deteriorated mental health, causing reduced energy or inclination to use these apps. Screening for good mental health among pregnant women is important; non-use of pregnancy apps may indicate risk of mental health deterioration among pregnant women. [Journal of Psychosocial Nursing and Mental Health Services, 61(1), 32-38.].

Impact of the COVID-19 Pandemic on the Mental Health of Users with Mental Illness of Home Visit Nursing Services in Japan.

This study aims to clarify the impact of COVID-19 on the mental health of users with mental illness of home visit nursing services. We sent a questionnaire to 1,740 home visit nursing station managers, 374 (21.5%) of whom responded. The total number of valid responses was 328, which amounted to 87.7% of the returned surveys. In total, 103 (31.4%) stations reported that their users' mental health deteriorated owing to the spread of COVID-19. Eighty-nine (86.4%) stations reported that their users' anxiety increased. More than 80% of the stations explained infection control measures to their users, but 194 (59.1%) stations answered that their users found it challenging to practice cleanliness. A total of 207 (63.1%) stations answered that the promotion of strategies for coping with stress is necessary for their users. Users with mental illness are vulnerable to stress and have a higher risk of death due to COVID-19. Thus, they should be carefully observed and referred to facilities if required. Home visit nursing staff have an important role to play in the preservation of the well-being of their users with mental illness during the COVID-19 pandemic.

Text Messaging for Psychiatric Outpatients: Effect on Help-Seeking and Self-Harming Behaviors.

A mobile phone intervention was developed and tested with 30 psychiatric outpatients with mental illness, who had high ideation for suicide. The intervention involved promoting help-seeking behaviors by sending text messages, including information about social welfare services and reminders about medical appointments, for 6 months. After the intervention period, the number of participants who used social services significantly increased, and more than 80% of participants reported that the text messaging service was helpful and useful. Compared to baseline, participants' self-harming behaviors decreased and the attending psychiatrists rated their suicide ideation as weaker. This is the first intervention study to promote psychiatric patients' help-seeking using text messaging, and although it was not a randomized controlled trial, this intervention has practical value and may lead to the prevention of suicide.

Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients.

OBJECTIVE: Dysphagia is a critical issue in amyotrophic lateral sclerosis (ALS) patients. An evaluation of swallowing function is important for assessing the risk of aspiration. We investigated the validity of tongue sonography compared with videofluoroscopic examination for ALS patients. METHODS: We investigated 18 ALS patients. Nine subjects underwent repeated investigations. All of the subjects underwent tongue sonography and videofluoroscopic examination. Additionally, tongue sonography was evaluated in 18 age- and sex-matched healthy volunteers. To determine tongue thickness, we measured the vertical distance from the surface of the mylohyoid muscle to the tongue dorsum using ultrasonography. RESULTS: In the ALS patients, the tongue was significantly thinner than in healthy subjects. Tongue thickness was associated with body mass index and onset type in the ALS patients (p=0.006). Temporal analyses of videofluoroscopy revealed that tongue thickness was associated with oral preparatory and transit time (p=0.032) but not with pharyngeal transit time. Repeated measurement data revealed a decrease in tongue thickness over the course of the measurements (p=0.002). CONCLUSIONS: In ALS patients, reduced tongue thickness suggests disease progression and tongue dysfunction. SIGNIFICANCE: Tongue sonography is a useful modality for the non-invasive and quantitative evaluation of tongue thickness and dysphagia in ALS patients.

Risk factors for postoperative dysphagia in oral cancer.

With the founding of its Oral Cancer Center at the Ichikawa General Hospital, Tokyo Dental College established a support system for patients and family members that not only provides surgery and other conventional cancer-oriented treatments, but also palliative care, nutritional support, rehabilitation, and discharge support. With this in mind, the present study sought to examine the nature of support for oral cancer patients with postoperative eating and swallowing disorders by investigating these disorders and identifying their risk factors. The study population comprised 75 surviving oral cancer patients (46 men and 29 women) discharged from the Tokyo Dental College Oral Cancer Center following treatment over a 2-year period from April 2009 to March 2011. Risk factors affecting eating and swallowing function were identified by statistical analysis. Mean age of the patients was 67.3±13.7 years. Fifteen patients had stage I cancer, while 25 had stage II, 13 had stage III, and 22 had stage IV. The feeding route at the time of discharge was oral feeding in 74 patients and a combination of oral and gastrostomy tube feeding in 1 patient. The Tokyo Dental College Ichikawa General Hospital has standardized the expert evaluation and rehabilitation of oral cancer patients with eating and swallowing disorders by establishing a multidisciplinary support system from the preoperative stage onwards. In this context, the results of our analysis of factors influencing the ability of oral cancer patients to orally ingest food after treatment suggest that preoperative cancer stage classification, neck dissection, and tracheotomy are all influential factors. Patients affected by these factors require further multidisciplinary treatment, which in turn necessitates more extensive coordination with other medical professionals and community health care providers.

Effect of cevimeline on radiation-induced salivary gland dysfunction and AQP5 in submandibular gland in mice.

The aim of this study was to clarify the effects of the muscarinic receptor agonist, cevimeline, on saliva flow and expression of aquaporin5 (AQP5) in submandibular gland after X-ray irradiation. Using a previously established radiation-induced xerostomia model mouse, saliva flow from at 7 days before irradiation to at 28 days after irradiation was investigated in mice that were treated with cevimeline before or after irradiation. Radiation caused a significant decrease in saliva flow compared with nonirradiated salivary glands. Cevimeline post-treatment also caused a significant decrease in saliva flow. In contrast, cevimeline pre-treatment did not significantly decrease saliva flow. Expression of AQP5 fluorescent intensity and mRNA were also analyzed. Irradiation significantly decreased expression of AQP5 in submandibular gland. However, pre-treatment with cevimeline prevented this decrease in AQP5 expression. These data suggest that pretreatment with cevimeline prevents radiation-induced xerostomia and radiation-induced decrease in expression of AQP5 in submandibular gland.