[Assessment of nutritional status in patients with primary lung cancer]. / Evaluation de l'état nutritionnel des patients atteints de cancer broncho-pulmonaire primitif.

BACKGROUND: Lung cancer is the leading cause of cancer-related mortality worldwide. Malnutrition is a common problem among patients with cancer, affecting up to 85% of patients with certain cancers and represents a risk factor for poor prognosis. aim: evaluate nutritional status in patients with lung cancer before and during treatment using nutritional risk index. METHODS: it's a prospective study conducted in pneumology IV department in Abderahman Mami hospital, from January to May 2011. 30 male patients with a lung cancer were included. Nutritional status was assessed before and during treatment based on anthropometric measures, biological markers and nutritional risk index (NRI). RESULTS: Mean age of patients was 58 ± 12 years, ranging from 19 to 82 years. 29 patients had non small cell lung cancer and one patient had small cell cancer. Malnutrition was noted in 14 patients (47%) before treatment according to the NRI. It was noted in 23 patients (77%) after three cycles of chemotherapy with severe malnutrition in 8 patients. Relationship between body mass index (BMI) and the NRI was linear, but NRI tends to evaluate more objectively risk of malnutrition in patients with lung cancer. CONCLUSION: Nutritional assessment in patient with lung cancer should be performed systematically, early and repeatedly. Several markers can be used such as BMI and NRI. Nutritional support will reduce morbidity and improve quality of life in patients with lung cancer.

[Pulmonary tuberculosis and diabetes. A retrospective study of 60 patients in Tunisia]. / La tuberculose pulmonaire provoque un déséquilibre du diabète Etude rétrospective de 60 malades en Tunisie.

BACKGROUND: Tuberculosis is a frequent infectious disease in Tunisia. The estimated case rate is 22.3 per 100,000 inhabitants. The risk of tuberculosis is 2 to 6 times greater in patients with diabetes. The purpose of this study was to analyze the particularities in the etiology, diagnosis and bacteriologic course of pulmonary tuberculosis in patients with diabetes and to evaluate the impact of tuberculosis on diabetes control. METHOD: This retrospective case-control study of 142 patients with confirmed pulmonary tuberculosis seen from 2000-2006 compared the 60 patients with diabetes with the 82 without diabetes. RESULTS: Diabetes was more frequent in older patients with tuberculosis and in women. 91.5% had type 2 diabetes. A history of contact with people with tuberculosis was significantly less frequent in the group with diabetes (13.3% vs 30.5%; p=0.01). Tuberculosis symptoms and their duration did not differ between the 2 groups. Basal lesions and cavitation occurred more frequently in the patients with diabetes, but this difference was not significant. The time for conversion to negative of sputum culture was longer in case patients (43+/-27 days) than in controls (28.2+/-20.5) (p=0.03). The proportion of patients with uncontrolled diabetes was elevated, and 50% required frequent insulin treatment. CONCLUSION: Tuberculosis is frequently associated with diabetes, usually due to reactivation of Mycobacterium tuberculosis. It is characterized by a longer time to culture conversion to negative and a risk of uncontrolled diabetes that requires frequent treatment adjustment and insulin use.

[Association of IGg multiple myeloma with pulmonary amyloidosis: about one case]. / Association myelome multiple à IG G--amylose pulmonaire: a propos d'un cas.

Pulmonary amyloidosis is a rather rare complication of multiple myeloma particularily the rare Ig D myeloma. It is often generalized and is seen in a late stage of the disease. We report a case of an Ig G myeloma complicated of a pulmonary amyloidosis in a 66-year-old man hospitalised for infectious pulmonary disease with a radiologic interstitial syndrome. Discovery of the multiple myeloma and of the amyloidosis was fortuitous.

[Lung cancer and chondromatous hamartoma: a case report]. / Association hamartochondrome pulmonaire et cancer bronchique, à propos d'un cas.

The association lung cancer with chondromatous hamartoma is frequent. We present a case of synchronous primary lung adenocarcinoma and chondromatous hamartoma. Although hamartoma is generally considered to be a benign tumor, there have been several reports of increased risk of lung cancer in patients with a chondromatous hamartoma. Therefore we recommend that patients with hamartoma should be submitted to a complete evaluation and to regular follow up, considering the risk of associated synchronous malignancy.