Mosque as a COVID-19 vaccination site in collaboration with a private clinic: A short report from Osaka, Japan.

Ethnic minorities are vulnerable to disasters, including the COVID-19 pandemic. Vaccination strategies that do not leave ethnic minorities behind are required. This is a report on the use of Osaka Islamic Center, a mosque, as a group vaccination site for an ethnic minority group in Osaka, Japan, from August to September 2021. We aimed to discuss (1) the process of turning the mosque to a vaccination site, (2) the linguistic and religious considerations made, and (3) the reasons people got vaccinated at the mosque. We interviewed stakeholders and vaccine recipients in December 2021. The survey shows that the mosque administrators voluntarily collaborated with a private clinic to become a vaccination site after learning of another mosque that had undertaken a similar venture. On the day of the vaccination, the mosque administrators' experiences with a large vaccination site informed the smooth operation of the site. They made linguistic considerations (i.e., having volunteers fill out medical questionnaires and administrators aid in language interpretation) and religious considerations (i.e., dividing the space and time of vaccination according to gender) for foreign Muslims. In particular, linguistic considerations were favorably accepted by vaccination recipients and were considered a factor that encouraged them to get vaccinated. The mosque also linked unvaccinated people to the clinic even after finishing vaccination at the mosque, suggesting that it may have played a role in ensuring they were not left behind. This case is expected to stimulate activities performed in mosques and by ethnic minority groups in future disasters.

COVID-19 vaccination at a mosque with multilingual and religious considerations for ethnic minorities: A case study in Kanagawa, Japan.

During a disaster, such as a pandemic, ethnic minorities tend to be left behind due to linguistic and religious differences. In the COVID-19 vaccination process, measures to include them are necessary, including the utilization of their resources and networks. The functions and challenges of such measures should be explored in real-world cases. We targeted a case in Ebina, Kanagawa, Japan, where a mosque, being a hub of foreign Muslims, was used as a vaccination site. This was the first, and the only, case in Japan with the involvement of the local government. We aimed to detail (1) the linguistic and religious responses at the mosque, (2) the perceptions of vaccine recipients regarding linguistic and religious issues and considerations, and (3) the problems that arose when using the mosque. We conducted an e-mail survey of the local government and a field survey-field observations and interviews with relevant stakeholders (e.g., mosque managers and female vaccinees). The surveys found various linguistic (e.g., interpretation by mosque-related volunteers) and religious (i.e., separating vaccination spaces based on gender) considerations provided at the mosque, which the vaccinees favorably accepted. The measure likely promoted vaccination by increasing the intention to vaccinate and closing the intention-behavior gap. If some identified problems (e.g., complaints from the Japanese) are mitigated, the function of the mosque as a vaccination site would be further enhanced. The results also support the significant potential of mosques in Muslim-minority societies to approach ethnic minorities in disasters, including pandemics.

Histopathologically TMA-like distribution of multiple organ thromboses following the initial dose of the BNT162b2 mRNA vaccine (Comirnaty, Pfizer/BioNTech): an autopsy case report.

BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread worldwide. Vaccination is now recommended as one of the effective countermeasures to control the pandemic or prevent the worsening of symptoms. However, its adverse effects have been attracting attention. Here, we report an autopsy case of multiple thromboses after receiving the first dose of the BNT162b2 mRNA vaccine (Comirnaty, Pfizer/BioNTech) in an elderly woman. CASE PRESENTATION: A 72-year-old woman with a history of diffuse large B-cell lymphoma in the stomach and hyperthyroidism received the first dose of the BNT162b2 mRNA vaccine and died 2 days later. The autopsy revealed multiple microthrombi in the heart, brain, liver, kidneys, and adrenal glands. The thrombi were CD61 and CD42b positive and were located in the blood vessels primarily in the pericardial aspect of the myocardium and subcapsular region of the adrenal glands; their diameters were approximately 5-40 µm. Macroscopically, a characteristic myocardial haemorrhage was observed, and the histopathology of the characteristic thrombus distribution, which differed from that of haemolytic uraemic syndrome and disseminated intravascular coagulation, suggested that the underlying pathophysiology may have been similar to that of thrombotic microangiopathy (TMA). CONCLUSION: This is the first report on a post-mortem case of multiple thromboses after the BNT162b2 mRNA vaccine. The component thrombus and characteristic distribution of the thrombi were similar to those of TMA, which differs completely from haemolytic uraemic syndrome or disseminated intravascular coagulation, after vaccination. Although rare, it is important to consider that fatal adverse reactions may occur after vaccination and that it is vital to conduct careful follow-up.

Mosque as a vaccination site for ethnic minority in Kanagawa, Japan: leaving no one behind amid the COVID-19 pandemic.

Ethnic minorities with different languages and religions are potentially vulnerable not only during natural hazard-related disasters, but also during the COVID-19 pandemic. Their vaccination coverage may be lower, and vaccination strategies should prevent them from being left behind. This report presents the first case in Japan where a mosque, being the hub of foreign Muslims, was used as a vaccination site from the end of July 2021. The targeted mosque was Ebina Mosque in Kanagawa Prefecture, and most of the vaccine recipients were foreign Muslims. The mosque differed from other vaccination sites in that reservations could be made easily through the managers, and linguistic diversity (i.e., the mosque managers and mosque-related volunteers served as interpreters) and gender were considered. These efforts are likely to have removed some barriers to vaccination for ethnic minorities and contributed to "no one will be left behind."

Mosques in Japan responding to COVID-19 pandemic: Infection prevention and support provision.

Religious activities tend to be conducted in enclosed, crowded, and close-contact settings, which have a high potential of transmitting the coronavirus disease, 2019 (COVID-19); therefore, religious communities are expected to take appropriate infection prevention measures. Meanwhile, during past disasters, religious communities have provided various types of support to affected people; hence, their role in disaster risk reduction has received much attention. In this study, we aimed to identify the infection prevention measures and support provision implemented by mosques-Islamic institutions managed and operated mainly by foreign Muslims living in Japan-during the one year from January 2020. We collected information from newspaper articles (18 articles on 19 mosques) and interviews with representatives of three mosques. We found that various infection control measures were implemented in mosques-refraining from mass prayers and closing buildings from an early stage (around February 2020); canceling large-scale events during the month of Ramadan; moving some activities online; and ensuring indoor ventilation and safe physical distance even when continuing face-to-face prayer activities. We also found that various types of support were provided by mosques-donating masks to the local government; listening to problems of people affected by COVID-19 regardless of their nationality; providing financial support to them; translating and disseminating information to foreign Muslims; and providing religious meals for them. This study provides actual examples of infection prevention measures taken by mosques in a Muslim-minority society and suggests that mosques appropriately responded to the needs of religious minorities during disasters, including COVID-19.

Synthesis of urea-tethered disaccharides in water.

A new method for the synthesis of urea-linked disaccharides in aqueous media has been developed. The key feature of our approach is two strained Steyermark-type gluco- and galactopyranosyl oxazolidinones. Each oxazolidinone is attached to a pyranose ring in a di-equatorial trans-annulation framework. Reaction of these oxazolidinones with 4-aminohexopyranose in water proceeded smoothly to afford the urea-tethered cellobiose and lactose analogues. The galactose-type oxazolidinone proved to be more reactive than the glucose-type, which is explained by the presence of an axial hydroxy group at C4 in the former.

Significance of kinetic degrees of freedom in operation of the actomyosin motor.

The actomyosin motor as a principal functional component of cell motility is highly coordinated in regulating the participating molecular components. At the same time, it has to be flexible and plastic enough to accommodate itself to a wide variety of operational conditions. We prepared two different types of actomyosin systems. One is a natural intact actomyosin system with no artificial constraint on the kinetic degrees of freedom of the actin filaments, and the other is a regulated one with actin filaments supplemented by intra- and intermolecular crosslinking to suppress the kinetic degrees of freedom to a certain extent. Crosslinked actomyosin systems were found to remain almost insensitive to calcium regulation even when intact troponin-tropomyosin regulatory component was incorporated. Both the ATPase and the motile activities of the actin filaments sliding on myosin molecules were markedly lowered by the crosslinking. In contrast, once the crosslinking was cleaved, both properties returned to the normal as with intact actomyosin systems.