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Zhonghua Nan Ke Xue ; 14(5): 448-50, 2008 May.
Artigo em Chinês | MEDLINE | ID: mdl-18572867

RESUMO

OBJECTIVE: To explore the impregnate occasion for male renal transplant recipients. METHODS: Twenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at the dose of 4.1-6 mg/[kg x d]), 11 in Group B (6-24 months and 2.1-4 mg/[kg x d]) and 8 in Group C (longer than 24 months and 1.3-2 mg/[kg x d]). The semen of the patients were detected and compared with those of 12 normal volunteers. RESULTS: Statistically significant differences were observed in sperm motility and sperm head deformity between Group A and C (P < 0.05), but not in pH value and sperm volume, vitality and concentration among the 3 groups (P > 0.05). CONCLUSION: For male renal transplant recipients, 2 years or longer after the transplantation is the most suitable time for impregnation.


Assuntos
Coito , Ciclosporina/administração & dosagem , Transplante de Rim , Adulto , Ciclosporina/uso terapêutico , Relação Dose-Resposta a Droga , Humanos , Concentração de Íons de Hidrogênio , Imunossupressores/administração & dosagem , Imunossupressores/uso terapêutico , Masculino , Período Pós-Operatório , Sêmen/química , Sêmen/citologia , Sêmen/efeitos dos fármacos , Contagem de Espermatozoides , Motilidade dos Espermatozoides/efeitos dos fármacos , Fatores de Tempo
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