RESUMO
Rugao and Haian belonging to First Branch of Su-Wan Liberated Area found fulminant cholera in 1946. The fulminant cholera spread throughout the Su-Wan Liberated Area in a short period of time. Thus, local mass and military led by CPC actively launched the Movement of Epidemic Prevention. They took some actions to clear up the circumstance, eliminate the pathogen, prevent the food contamination and cut off the route of transmission. Vaccination was carried out on a large scale. As a result of these measure, the fulminant cholera was efficiently controlled.
Assuntos
Cólera , Epidemias/história , Militares , China , Cólera/epidemiologia , Cólera/prevenção & controle , Controle de Doenças Transmissíveis/métodos , Epidemias/prevenção & controle , História do Século XX , Humanos , Programas de Imunização , VacinaçãoRESUMO
OBJECTIVES: The fronto-limbic system plays critical roles in cognitive functions, including emotion. This is supported by recent reports in the studies of major depressive disorder using diffusion tensor imaging of the brain. This study examined white matter integrity and correlations to cognitive function in treatment-naive adult patients with major depressive disorder. METHODS: Fractional anisotropy values, derived from diffusion tensor imaging, were compared in 18 treatment-naïve adult patients with major depressive disorder and 18 well-matched healthy controls by voxel-based analysis. Correlation of fractional anisotropy with performance of cognitive tests was also analysed. RESULTS: Lower fractional anisotropy values in the bilateral medial frontal gyri, right subgyral frontal and temporal lobes, and left middle frontal and cingulate gyri were observed in patients than in controls. However, no correlation between mean fractional anisotropy values and cognitive scores was found. CONCLUSION: These findings support the notion that deficit of white matter integrity in the fronto-limbic system may be the neural substrate of major depressive disorder.