Influenza Vaccine Effectiveness against Hospitalization, Season 2021/22: A Test-Negative Design Study in Barcelona.

BACKGROUND: Vaccination is considered the most effective measure for preventing influenza and its complications. The influenza vaccine effectiveness (IVE) varies annually due to the evolution of influenza viruses and the update of vaccine composition. Assessing the IVE is crucial to facilitate decision making in public health policies. AIM: to estimate the IVE against hospitalization and its determinants in the 2021/22 season in a Spanish tertiary hospital. METHODS: We conducted a prospective observational test-negative design study within the Development of Robust and Innovative Vaccine Effectiveness (DRIVE) project. Hospitalized patients with severe acute respiratory infection (SARI) and an available influenza reverse transcription polymerase chain reaction (RT-PCR) were selected and classified as cases (positive influenza RT-PCR) or controls (negative influenza RT-PCR). Vaccine information was obtained from electronic clinical records shared by public healthcare providers. Information about potential confounders was obtained from hospital clinical registries. The IVE was calculated by subtracting the ratio of the odds of vaccination in cases and controls from one, as a percentage (IVE = (1 - odds ratio (OR)) × 100). Multivariate IVE estimates were calculated using logistic regression. RESULTS: In total, 260 severe acute respiratory infections (SARI) were identified, of which 34 were positive for influenza, and all were subtype A(H3N2). Fifty-three percent were vaccinated. Adjusted IVE against hospitalization was 26.4% (95% CI -69% to 112%). IVE determinants could not be explored due to sample size limitations. CONCLUSION: Our data revealed non-significant moderate vaccine effectiveness against hospitalization for the 2021/2022 season.

No calorie comfort: Viewing and drawing "comfort foods" similarly augment positive mood for those with depression.

Based on behavioral and neurobiological data, we tested the hypothesis that viewing/drawing visual images of comfort foods in the absence of eating will increase positive mood and that this effect is augmented for those with clinical symptoms of depression. A counterbalanced design was used for 60 participants with and without clinical symptoms in two variations: food image and food art. In each variation, participants viewed/drew foods high or low in fat/sugar; pre-post mood was recorded. Results show a consistent pattern: viewing/drawing comfort foods [food image (95% confidence interval): 2.72-4.85; food art (95% confidence interval): 2.65-4.62] and fruits [food image (95% confidence interval): 1.20-2.23; food art (95% confidence interval): 1.51-2.56] enhanced mood. For comfort foods, mood was augmented for those with clinical symptoms of depression [food image (95% confidence interval): 0.95-3.59; food art (95% confidence interval): 0.97-3.46]. Findings corroborate previous data and reveal a novel finding of augmented mood increases for those with clinical symptoms.

Malnutrición del adulto mayor y factores asociados en el distrito de Masma Chicche, Junín, Perú / Malnutrition and associated factors in the elder population of Masma Chicche, Junin, Peru

Objetivo: Determinar el estado nutricional y los factores asociados a malnutrición en el adulto mayor en la comunidad de Masma Chicche, Junín. Material y métodos: Estudio descriptivo transversal realizado en personas mayores de 60 años distrito de Masma Chicche, Junín, Perú. Se utilizó el Mini Nutritional Assesment (MNA) para la evaluación nutricional e instrumentos de valoración geriátrica integral para establecer la presencia de depresión (Yesavage), estado funcional (Katz), deterioro cognitivo (Pfeiffer), salud oral (GOHA) y estado social (Guijon). Se realizó estadística descriptiva, chi cuadrado y ANOVA para determinar asociación entre las variables. Se consideró un p < 0,05 como significativo. Resultados: Se encuestaron a 72 personas. La prevalencia de malnutrición fue 29,9%; 57,9% en riesgo de malnutrición. El 69,4% presentaban depresión y riesgo de la misma; 27,8% mostró deterioro cognitivo; 93,1% presentaba percepción negativa de su salud oral; 51,4% eran dependientes funcionales y el 100% poseía algún problema social. Se encontró asociación de malnutrición con las variables, sexo masculino y presencia de depresión. Conclusiones: En la comunidad de Masma Chicche, alrededor de la tercera parte de la población tiene malnutrición la que está asociada con el sexo masculino y la presencia de depresión.

Objective: Determine the nutritional status and factors associated to malnutrition in the elder population of Masma Chicche, Junin. Methods: Cross-sectional study in persons above 60 years of age in the district of Masma Chicche, Junin. The nutritional evaluation was performed using the mini nutritional assessment method (MNA); depression was evaluated using an integral geriatric valoration scale (Yesavage); functional status was evaluated using the Katz´s method; cognitive deterioration was measured by the Pfeiffer´s method; oral health was evaluated by the GOHA´s method and social status by the Guijon´s method. Descriptive statistics, Chi square and ANOVA tests were used to contrast variables, a p value <0.05 was considered significant. Results: 72 elder persons were evaluated; the prevalence of malnutrition was 29.9%; 57.9% were at risk for malnutrition. Prevalence of depression was 69.4%; 27.8% had cognitive deterioration; 93.1% had negative perception of their oral health; 51.4% were functionally dependant and 100% had any kind of social problem. Malnutrition was associated with age, male gender and depression. Conclusions: Almost one third of the elder population of Masma Chicche has malnutrition, which is associated with male gender and depression.