1.
Mutat Res
; 62(2): 393-9, 1979 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-388215
2.
Mutat Res
; 51(3): 311-8, 1978 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-362176
RESUMO
25 polynuclear hydrocarbons were tested for mutagenicity using the Ames Assay and the results were compared with existing carcinogenicity data. The assessment of the predictive value of this particular short-term test showed a 58% positive and a 41% negative correlation.
Assuntos
Benzo(a)Antracenos/farmacologia , Benzopirenos/farmacologia , Carcinógenos , Mutagênicos , Relação Dose-Resposta a Droga , Técnicas Genéticas , Salmonella typhimurium
3.
Mutat Res
; 51(3): 319-26, 1978 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-362177
RESUMO
The carcinogenicity and mutagenicity of 26 nitrosamines were compared to help validate the predictability of a short-term in vitro test. 80% of the compounds showed agreement between the two characteristics, while 20% did not. Of the latter group, 8% were false positives and 12% were false negatives.
Assuntos
Carcinógenos , Mutagênicos , Nitrosaminas/farmacologia , Relação Dose-Resposta a Droga , Técnicas Genéticas , Salmonella typhimurium
4.
Eur J Cancer (1965)
; 14(7): 793-7, 1978 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-658104