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1.
Osteoporos Int ; 31(3): 465-474, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31897545

RESUMO

This study examined hip fracture hospitalisation trends and predictors of access to rehabilitation for adults aged ≥ 65 years living with and without dementia. The hospitalisation rate was 2.5 times higher for adults living with dementia and adults who lived in aged care were between 4.8 and 9.3 times less likely to receive rehabilitation. INTRODUCTION: To examine hip fracture hospitalisation temporal trends, health outcomes, and predictors of access to in-hospital rehabilitation for older adults living with and without dementia. METHODS: A population-based retrospective cohort study of adults aged ≥ 65 years hospitalised with a hip fracture during 2007-2017 in New South Wales, Australia. RESULTS: Of the 69,370 hip fracture hospitalisations, 27.1% were adults living with dementia. The hip fracture hospitalisation rate was 2.5 times higher for adults living with dementia compared with adults with no dementia (1186.6 vs 492.9 per 100,000 population). The rate declined by 6.1% per year (95%CI - 6.6 to - 5.5) for adults living with dementia and increased by 1.0% per year (95%CI 0.5-1.5) for adults with no dementia. Multivariable associations identified that adults living with dementia who experienced high frailty and increasing age were between 1.6 and 1.8 times less likely to receive in-hospital rehabilitation. Adults who were living in long-term aged care facilities were between 4.8 and 9.3 times less likely to receive in-hospital rehabilitation which varied by the presence of dementia or delirium. CONCLUSION: Consistent criteria should be applied to determine rehabilitation access, and rehabilitation services designed for older adults living with dementia or in aged care are needed. HIGHLIGHTS: • Adults living with dementia were able to make functional gains following hip fracture rehabilitation. • Need to determine consistent criteria to determine access to hip fracture rehabilitation. • Rehabilitation services specifically designed for adults living with dementia or in aged care are needed.


Assuntos
Demência , Fraturas do Quadril , Assistência ao Convalescente , Idoso , Austrália , Estudos de Coortes , Demência/epidemiologia , Feminino , Fraturas do Quadril/epidemiologia , Hospitalização , Hospitais , Humanos , Masculino , Avaliação de Resultados em Cuidados de Saúde , Alta do Paciente , Estudos Retrospectivos
2.
J Autism Dev Disord ; 49(12): 4919-4928, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31473948

RESUMO

Knowledge about the quality of care delivered to children with autism spectrum disorders (ASD) in relation to that recommended by clinical practice guidelines (CPGs) is limited. ASD care quality indicators were developed from CPGs and validated by experts, then used to assess the quality of care delivered by general practitioners (GPs) and pediatricians in Australia. Data were retrospectively collected from the medical records of 228 children (≤ 15 years) with ASD for 2012-2013. Overall quality of care was high, but with considerable variation among indicators, and between GPs and pediatricians-e.g., GPs were less likely to complete the assessment care bundle (61%; 95% CI 21-92). Findings highlight potential areas for improvement in the need for standardized criteria for diagnosis.


Assuntos
Transtorno do Espectro Autista/terapia , Medicina Geral/normas , Qualidade da Assistência à Saúde , Austrália , Transtorno do Espectro Autista/diagnóstico , Transtorno do Espectro Autista/epidemiologia , Criança , Pré-Escolar , Feminino , Medicina Geral/estatística & dados numéricos , Humanos , Masculino , Prontuários Médicos/estatística & dados numéricos
5.
Science ; 168(3935): 1108-9, 1970 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-5441686

RESUMO

An experimental method has been devised for the study of the inter-action of bimolecular (black) lipid membrane and protein in which 8-anilino-1-naphthalenesulfonic acid is used as a fluorescent probe. The presence of phospho-lipid in the membrane is necessary for the enhanced fluorescence.


Assuntos
Membranas Artificiais , Fosfolipídeos , Soroalbumina Bovina , Fluorescência , Naftalenos , Ácidos Sulfônicos
8.
Biophys J ; 6(6): 813-23, 1966 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-5972380

RESUMO

Diffusion of the chloride salts of Li, Na, K, Rb, and Cs from water into 1-butanol and from 1-butanol into water was examined at temperatures from 13-40 degrees C. Distribution coefficients, interfacial transfer coefficients, Arrhenius activation energy, free energy of activation, enthalpy, and entropy of activation were determined for the diffusion of these salts across the alcohol-water interface. The results indicate that the entropy decrease made the major contribution to the change in the free energy of activation.


Assuntos
Álcoois , Transporte Biológico , Cloretos , Césio , Fenômenos Químicos , Físico-Química , Lítio , Membranas Artificiais , Modelos Teóricos , Cloreto de Potássio , Rubídio , Cloreto de Sódio
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