Bilateral erector spinae plane blocks in children undergoing cardiac surgery: A randomized, controlled study.

STUDY OBJECTIVE: We aimed to test the hypothesis that erector spinae plane block (ESPB) provides efficient analgesia and reduces postoperative morphine consumption in children undergoing cardiac surgery with median sternotomy. DESIGN: A prospective, blinded, randomized, controlled study. SETTING: A tertiary university hospital, operating room and intensive care unit. PATIENTS: Forty children aged 2-10 years, who underwent cardiac surgery with median sternotomy. The patients were randomly divided into the block group (Group B) and the control group (Group C). INTERVENTIONS: Group B (n = 20) were treated with ultrasound-guided bilateral ESPB at the level of the T4-T5 transverse process, whereas no block was administered in Group C (n = 20). In all children, intravenous morphine at 0.05 mg/kg was used whenever the modified objective pain score (MOPS) ≥4 for postoperative analgesia. MEASUREMENTS: The MOPS and Ramsay sedation score (RSS) were assessed at 0, 1, 2, 4, 6, 8, 10, 12, 16, 20 and 24 h postoperatively. Total morphine consumption at 24 h, extubation time and length of intensive care unit (ICU) stay was also evaluated and recorded. MAIN RESULTS: Bilateral ESPB significantly decreased the consumption of morphine in the first 24 h, postoperatively. During the postoperative 24-h follow-up, 11 children in Group C requested morphine and the cumulative dose of morphine was 0.83 ± 0.91 mg, while 4 children in Group B requested morphine and the cumulative dose of morphine was 0.26 ± 0.59 mg (p = 0.043). There was no significant difference between Groups B and C in terms of MOPS and RSS values, extubation time or length of ICU stay. CONCLUSION: Ultrasound-guided bilateral ESPB with bupivacaine provides efficient postoperative analgesia and reduces postoperative morphine consumption at 24 h in children undergoing cardiac surgery.

[Metabolic syndrome in patients after coronary bypass surgery: prevalence and compliance with treatment]. / Koroner baypas sonrasi hastalarda metabolik sendrom sikligi ve tedaviye uyum oranlari.

OBJECTIVE: The aim of this study was to evaluate the prevalence of metabolic syndrome (MS) and its components, to determine the patients' compliance with pharmacological therapy and lifestyle modification, and to clarify the association of demographic and socioeconomic factors with the MS in Turkish patients with prior coronary artery bypass surgery (CABG). METHODS: Two hundred and seventy-three patients (age range 35-77, 208 men) were interviewed and examined 1.0-2.2 years after CABG. RESULTS: The prevalence of MS was 44.8% (55.4% among women and 41.3% among men). The most prevalent metabolic risk factor was visceral obesity among females, and elevated blood pressure among males. Rates for regular physical activity were lower in patients with MS, compared with those without MS (36.9% vs. 47.7%, p<0.05). Compared with patients without MS, use of aspirin was lower among patients with MS (84.4% vs. 93.4%, p<0.05). Logistic regression analysis revealed an independent association of age>65 years and low educational level with MS. CONCLUSION: We found a high prevalence of metabolic syndrome and its components among patients with prior CABG. Patients with MS had lower rate of regular physical activity and aspirin use, compared with those without MS.