RESUMO
To determine the correlation between the bacterial flora of vagina or amniotic fluid of the mother and the oral cavity of the newborn, we made a prospective bacteriologic study in 43 newborns; 18 of them were born by cesarean section and 25 by vaginal delivery. The samples for the study were taken at birth, at 12 and 24 hours of life. In the newborns delivery by cesarean section was not correlation between the microorganism founded in amniotic fluid and neonatal oral cavity. In the neonates obtained by vaginal delivery there was correlation between the microorganisms in the oral cavity and the maternal vaginal flora. The results support the hypothesis that the bacteria colonize the oral cavity at birth comes from the vaginal cavity contamination of the mother.
Assuntos
Líquido Amniótico/microbiologia , Boca/microbiologia , Vagina/microbiologia , Feminino , Humanos , Recém-Nascido , Estudos ProspectivosRESUMO
With the object to determine the utility of C-reactive protein (CRP) in the diagnosis of neonatal sepsis. We proceeded to create the prospective study of cases and controls of newborn included in the study of neonatal sepsis in the Instituto Nacional de Perinatologia. We measured the seric CRP in samples obtained by capillary punction simultaneously with blood culture and/or CSF culture, for bacterial infection criteria. We included 64 newborn divided in two groups: 42 patients were not infected and 22 cases had positive cultures. The results in the uninfected newborn group of CRP were negative to positive dilutions 1:32; with the newborn infected the CRP had values of 1:32 to 1:2048. The probability to find values equal or major to 1:32 in the infected newborn with positive cultures the CRP have values of sensitivity of 91% and specificity of 93% to get this values. We accept that the CRP could be used systematically for the diagnosis of neonatal sepsis, being a simple procedure and accessible for use in the newborn with sepsis suspicion.